The detail information of Epilepsy
OMIA Basic Information

Possible human homologues (MIM numbers):

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB30 Belgian Shepherd Dog 61-66 cm (male), 55.9-61 cm (female) 24.9-34 kg (male), 20.4-27.2 kg (female) Belgium
CB79 Collie 61-66 cm (male), 55.9-61 cm (female) 27.2-34 kg (male), 22.7-29.5 kg (female)
CB104 Finnish Spitz 44.5-50.8 cm (male), 39.4-45.7 cm (female) 11.3-15 kg (male), 9.1-12.7 kg (female) Finland
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Belanger,J.M.,Famula,T.R.,Gershony,L.C.,Palij,M.K.,Oberbauer,A.M.: :
Genome-wide association analysis of idiopathic epilepsy in the Belgian shepherd. Canine Genet Epidemiol 7:12, 2020.
DOI: https://doi.org/10.1186/s40575-020-00091-x .
2020 Karlskov-Mortensen,P.: :
Risk loci for idiopathic epilepsy in Belgian Shepherd dogs. Anim Genet :, 2020.
Pubmed reference: 33259081 . DOI: 10.1111/age.13030 .
2019 VanMeervenne,S.,Volk,H.A.,Verhoeven,P.S.,VanHam,L.,O'Neill,D.G.: :
Associations between neutering and idiopathic epilepsy in Labrador retrievers and Border collies under primary veterinary care in the UK. Vet J 252:105354, 2019.
Pubmed reference: 31554590 . DOI: 10.1016/j.tvjl.2019.105354 .
2018 Hartmann,A.,vonKlopmann,C.,Lautenschläger,I.E.,Scholz,V.B.,Schmidt,M.J.: :
Quantitative analysis of brain perfusion parameters in dogs with idiopathic epilepsy by use of magnetic resonance imaging. Am J Vet Res 79:433-442, 2018.
Pubmed reference: 29583046 . DOI: 10.2460/ajvr.79.4.433 .
2017 Belanger,J.M.,Bellumori,T.P.,Bannasch,D.L.,Famula,T.R.,Oberbauer,A.M.: :
Correlation of neuter status and expression of heritable disorders. Canine Genet Epidemiol 4:6, 2017.
Pubmed reference: 28560045 . DOI: 10.1186/s40575-017-0044-6 .
2016 Hasegawa,D.: :
Diagnostic techniques to detect the epileptogenic zone: Pathophysiological and presurgical analysis of epilepsy in dogs and cats. Vet J :, 2016.
Pubmed reference: 27052436 . DOI: 10.1016/j.tvjl.2016.03.005 .
2016 Hayward,J.J.,Castelhano,M.G.,Oliveira,K.C.,Corey,E.,Balkman,C.,Baxter,T.L.,Casal,M.L.,Center,S.A.,Fang,M.,Garrison,S.J.,Kalla,S.E.,Korniliev,P.,Kotlikoff,M.I.,Moise,N.S.,Shannon,L.M.,Simpson,K.W.,Sutter,N.B.,Todhunter,R.J.,Boyko,A.R.: :
Complex disease and phenotype mapping in the domestic dog. Nat Commun 7:10460, 2016.
Pubmed reference: 26795439 . DOI: 10.1038/ncomms10460 .
2016 Kirkham,E.: :
Study on epilepsy in the Italian spinone. Vet Rec 178:146, 2016.
Pubmed reference: 26851106 . DOI: 10.1136/vr.i689 .
2016 Packer,R.M.,Law,T.H.,Davies,E.,Zanghi,B.,Pan,Y.,Volk,H.A.: :
Effects of a ketogenic diet on ADHD-like behavior in dogs with idiopathic epilepsy. Epilepsy Behav 55:62-8, 2016.
Pubmed reference: 26773515 . DOI: 10.1016/j.yebeh.2015.11.014 .
2016 Packer,R.M.,Lucas,R.,Volk,H.A.: :
Owner perception of focal seizures in canine epilepsy. Vet Rec :, 2016.
Pubmed reference: 27856943 . DOI: 10.1136/vr.104099 .
2016 Packer,R.M.,Shihab,N.K.,Torres,B.B.,Volk,H.A.: :
Risk factors for cluster seizures in canine idiopathic epilepsy. Res Vet Sci 105:136-8, 2016.
Pubmed reference: 27033922 . DOI: 10.1016/j.rvsc.2016.02.005 .
2016 Uriarte,A.,MaestroSaiz,I.: :
Canine versus human epilepsy: are we up to date? J Small Anim Pract 57:115-21, 2016.
Pubmed reference: 26931499 . DOI: 10.1111/jsap.12437 .
2015 Heske,L.,Körberg,I.B.,Nødtvedt,A.,Jäderlund,K.H.: :
Clinical characteristics of epilepsy of unknown origin in the Rottweiler breed. Acta Vet Scand 57:75, 2015.
Pubmed reference: 26546467 . DOI: 10.1186/s13028-015-0168-1 .
2015 Koskinen,L.L.,Seppälä,E.H.,Belanger,J.M.,Arumilli,M.,Hakosalo,O.,Jokinen,P.,Nevalainen,E.M.,Viitmaa,R.,Jokinen,T.S.,Oberbauer,A.M.,Lohi,H.: :
Identification of a common risk haplotype for canine idiopathic epilepsy in the ADAM23 gene. BMC Genomics 16:465, 2015.
Pubmed reference: 26084559 . DOI: 10.1186/s12864-015-1651-9 .
2015 Oberbauer,A.M.,Belanger,J.M.,Bellumori,T.,Bannasch,D.L.,Famula,T.R.: :
Ten inherited disorders in purebred dogs by functional breed groupings. Canine Genet Epidemiol 2:9, 2015.
Pubmed reference: 26401337 . DOI: 10.1186/s40575-015-0021-x .
2015 Packer,R.M.,Nye,G.,Porter,S.E.,Volk,H.A.: :
Assessment into the usage of levetiracetam in a canine epilepsy clinic. BMC Vet Res 11:25, 2015.
Pubmed reference: 25889090 . DOI: 10.1186/s12917-015-0340-x .
2015 Rusbridge,C.,Long,S.,Jovanovik,J.,Milne,M.,Berendt,M.,Bhatti,S.F.,DeRisio,L.,Farqhuar,R.G.,Fischer,A.,Matiasek,K.,Muñana,K.,Patterson,E.E.,Pakozdy,A.,Penderis,J.,Platt,S.,Podell,M.,Potschka,H.,Stein,V.M.,Tipold,A.,Volk,H.A.: :
International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol. BMC Vet Res 11:194, 2015.
Pubmed reference: 26319136 . DOI: 10.1186/s12917-015-0466-x .
2014 Charalambous,M.,Brodbelt,D.,Volk,H.A.: :
Treatment in canine epilepsy - a systematic review. BMC Vet Res 10:257, 2014.
Pubmed reference: 25338624 . DOI: 10.1186/s12917-014-0257-9 .
2014 Gindiciosi,B.,Palus,V.,Eminaga,S.,Villiers,E.,BrutoCherubini,G.: :
Serum bromide concentrations following loading dose in epileptic dogs. J Small Anim Pract :, 2014.
Pubmed reference: 24433448 . DOI: 10.1111/jsap.12173 .
2014 Heske,L.,Berendt,M.,Jäderlund,K.H.,Egenvall,A.,Nødtvedt,A.: :
Validation of the diagnosis canine epilepsy in a Swedish animal insurance database against practice records. Prev Vet Med 114:145-50, 2014.
Pubmed reference: 24680294 . DOI: 10.1016/j.prevetmed.2014.03.003 .
2014 Heske,L.,Nødtvedt,A.,Jäderlund,K.H.,Berendt,M.,Egenvall,A.: :
A cohort study of epilepsy among 665,000 insured dogs: incidence, mortality and survival after diagnosis. Vet J 202:471-6, 2014.
Pubmed reference: 25457266 . DOI: 10.1016/j.tvjl.2014.09.023 .
2014 Howbert,J.J.,Patterson,E.E.,Stead,S.M.,Brinkmann,B.,Vasoli,V.,Crepeau,D.,Vite,C.H.,Sturges,B.,Ruedebusch,V.,Mavoori,J.,Leyde,K.,Sheffield,W.D.,Litt,B.,Worrell,G.A.: :
Forecasting seizures in dogs with naturally occurring epilepsy. PLoS One 9:e81920, 2014.
Pubmed reference: 24416133 . DOI: 10.1371/journal.pone.0081920 .
2014 Viitmaa,R.,Haaparanta-Solin,M.,Snellman,M.,Cizinauskas,S.,Orro,T.,Kuusela,E.,Johansson,J.,Viljanen,T.,Jokinen,T.S.,Bergamasco,L.,Metsähonkala,L.: :
Cerebral glucose utilization measured with high resolution positron emission tomography in epileptic Finnish Spitz dogs and healthy dogs. Vet Radiol Ultrasound :, 2014.
Pubmed reference: 24547764 . DOI: 10.1111/vru.12147 .
2014 Wessmann,A.,Volk,H.A.,Parkin,T.,Ortega,M.,Anderson,T.J.: :
Evaluation of quality of life in dogs with idiopathic epilepsy. J Vet Intern Med 28:510-4, 2014.
Pubmed reference: 24612035 . DOI: 10.1111/jvim.12328 .
2013 Bellumori,T.P.,Famula,T.R.,Bannasch,D.L.,Belanger,J.M.,Oberbauer,A.M.: :
Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995-2010). J Am Vet Med Assoc 242:1549-55, 2013.
Pubmed reference: 23683021 . DOI: 10.2460/javma.242.11.1549 .
2013 Chai,O.,Sommer,A.,Zimmerman,G.,Soreq,H.,Friedman,A.,Bdolah-Abram,T.,Aroch,I.,Shamir,M.H.: :
Acetylcholinesterase activity in the cerebrospinal fluid of dogs with seizures. Vet J :, 2013.
Pubmed reference: 23988333 . DOI: 10.1016/j.tvjl.2013.06.027 .
2013 Coles,L.D.,Patterson,E.E.,Sheffield,W.D.,Mavoori,J.,Higgins,J.,Michael,B.,Leyde,K.,Cloyd,J.C.,Litt,B.,Vite,C.,Worrell,G.A.: :
Feasibility study of a caregiver seizure alert system in canine epilepsy. Epilepsy Res :, 2013.
Pubmed reference: 23962794 . DOI: 10.1016/j.eplepsyres.2013.06.007 .
2013 Creevy,K.E.,Gagnepain,J.F.,Platt,S.R.,Edwards,G.L.,Kent,M.: :
Comparison of concentrations of γ-aminobutyric acid and glutamate in cerebrospinal fluid of dogs with idiopathic epilepsy with and without seizure-related magnetic resonance imaging hyperintense areas in the limbic system. Am J Vet Res 74:1118-25, 2013.
Pubmed reference: 23879850 . DOI: 10.2460/ajvr.74.8.1118 .
2013 Ekenstedt,K.J.,Oberbauer,A.M.: :
Inherited epilepsy in dogs. Top Companion Anim Med 28:51-8, 2013.
Pubmed reference: 24070682 . DOI: 10.1053/j.tcam.2013.07.001 .
2013 Gesell,F.K.,Zoerner,A.A.,Brauer,C.,Engeli,S.,Tsikas,D.,Tipold,A.: :
Alterations of endocannabinoids in cerebrospinal fluid of dogs with epileptic seizure disorder. BMC Vet Res 9:262, 2013.
Pubmed reference: 24370333 . DOI: 10.1186/1746-6148-9-262 .
2013 Harcourt-Brown,T.: :
Canine epilepsy: integrating research in practice. Vet Rec 172:336-7, 2013.
Pubmed reference: 23539654 . DOI: 10.1136/vr.f1979 .
2013 Jeffery,N.D.: :
Canine epilepsy: In search of a fitting end. Vet J :, 2013.
Pubmed reference: 24440441 . DOI: 10.1016/j.tvjl.2013.11.017 .
2013 Jokinen,T.S.,Haaparanta-Solin,M.,Viitmaa,R.,Grönroos,T.J.,Johansson,J.,Bergamasco,L.,Snellman,M.,Metsähonkala,L.: :
FDG-PET in healthy and epileptic Lagotto Romagnolo dogs and changes in brain glucose uptake with age. Vet Radiol Ultrasound :, 2013.
Pubmed reference: 24354474 . DOI: 10.1111/vru.12129 .
2013 Kearsley-Fleet,L.,O'Neill,D.G.,Volk,H.A.,Church,D.B.,Brodbelt,D.C.: :
Prevalence and risk factors for canine epilepsy of unknown origin in the UK. Vet Rec :, 2013.
Pubmed reference: 23300065 . DOI: 10.1136/vr.101133 .
2013 Klang,A.,Leschnik,M.,Schmidt,P.,Pakozdy,A.: :
Bilateral Hippocampal Malformation and Concurrent Granulomatous Meningoencephalitis in a Dog with Refractory Epilepsy. J Comp Pathol :, 2013.
Pubmed reference: 24461687 . DOI: 10.1016/j.jcpa.2013.11.212 .
2013 Löscher,W.,Hoffmann,K.,Twele,F.,Potschka,H.,Töllner,K.: :
The novel antiepileptic drug imepitoin compares favourably to other GABA-mimetic drugs in a seizure threshold model in mice and dogs. Pharmacol Res :, 2013.
Pubmed reference: 24056205 . DOI: 10.1016/j.phrs.2013.09.003 .
2013 Pivetta,M.,DeRisio,L.,Newton,R.,Dennis,R.: :
Prevalence of lateral ventricle asymmetry in brain MRI studies of neurologically normal dogs and dogs with idiopathic epilepsy. Vet Radiol Ultrasound :, 2013.
Pubmed reference: 23782324 . DOI: 10.1111/vru.12063 .
2013 Potschka,H.,Fischer,A.,vonRüden,E.L.,Hülsmeyer,V.,Baumgärtner,W.: :
Canine epilepsy as a translational model? Epilepsia 54:571-9, 2013.
Pubmed reference: 23506100 . DOI: 10.1111/epi.12138 .
2013 Preston,S.M.,Shihab,N.,Volk,H.A.: :
Public perception of epilepsy in dogs is more favorable than in humans. Epilepsy Behav 27:243-6, 2013.
Pubmed reference: 23466251 . DOI: 10.1016/j.yebeh.2013.01.019 .
2013 Sakurai,M.,Morita,T.,Takeuchi,T.,Shimada,A.: :
Relationship of angiogenesis and microglial activation to seizure-induced neuronal death in the cerebral cortex of Shetland Sheepdogs with familial epilepsy. Am J Vet Res 74:763-70, 2013.
Pubmed reference: 23627390 . DOI: 10.2460/ajvr.74.5.763 .
2013 Schwartz,M.,Muñana,K.R.,Nettifee-Osborne,J.: :
Assessment of the prevalence and clinical features of cryptogenic epilepsy in dogs: 45 cases (2003-2011). J Am Vet Med Assoc 242:651-7, 2013.
Pubmed reference: 23402412 . DOI: 10.2460/javma.242.5.651 .
2013 Scorza,C.A.,Calderazzo,L.,Cavalheiro,E.A.,Cysneiros,R.M.,Scorza,F.A.: :
Sudden unexpected death in dogs with epilepsy: Risks versus benefits of omega-3 fatty acid supplementation for man's best friend. Epilepsy Behav :, 2013.
Pubmed reference: 23619429 . DOI: 10.1016/j.yebeh.2013.02.021 .
2013 Viitmaa,R.,Cizinauskas,S.,Orro,T.,Niilo-Rämä,M.,Gordin,E.,Lohi,H.,Seppälä,E.H.,Bragge,H.,Snellman,M.: :
Phenotype, inheritance characteristics, and risk factors for idiopathic epilepsy in Finnish Spitz dogs. J Am Vet Med Assoc 243:1001-9, 2013.
Pubmed reference: 24050567 . DOI: 10.2460/javma.243.7.1001 .
2013 Volk,H.A.,Davies,E.: :
Trial of a novel diet for epilepsy in dogs. Vet Rec 172:319-20, 2013.
Pubmed reference: 23525817 . DOI: 10.1136/vr.f1869 .
2012 Akos,P.,Thalhammer,J.G.,Leschnik,M.,Halász,P.: :
Electroencephalographic examination of epileptic dogs under propofol restraint. Acta Vet Hung 60:309-24, 2012.
Pubmed reference: 22903076 . DOI: 10.1556/AVet.2012.026 .
2012 Arrol,L.,Penderis,J.,Garosi,L.,Cripps,P.,Gutierrez-Quintana,R.,Gonçalves,R.: :
Aetiology and long-term outcome of juvenile epilepsy in 136 dogs. Vet Rec 170:335, 2012.
Pubmed reference: 22266685 . DOI: 10.1136/vr.100316 .
2012 Borschensky,C.M.,Woolley,J.S.,Kipar,A.,Herden,C.: :
Neurogenesis in a young dog with epileptic seizures. Vet Pathol 49:766-70, 2012.
Pubmed reference: 22194355 . DOI: 10.1177/0300985811429308 .
2012 Ekenstedt,K.J.,Patterson,E.E.,Mickelson,J.R.: :
Canine epilepsy genetics. Mamm Genome 23:28-39, 2012.
Pubmed reference: 22037590 . DOI: 10.1007/s00335-011-9362-2 .
2012 Gulløv,C.H.,Toft,N.,Berendt,M.: :
A Longitudinal Study of Survival in Belgian Shepherds with Genetic Epilepsy. J Vet Intern Med :, 2012.
Pubmed reference: 22882455 . DOI: 10.1111/j.1939-1676.2012.00977.x .
2012 Monteiro,R.,Adams,V.,Keys,D.,Platt,S.R.: :
Canine idiopathic epilepsy: prevalence, risk factors and outcome associated with cluster seizures and status epilepticus. J Small Anim Pract 53:526-30, 2012.
Pubmed reference: 22835069 . DOI: 10.1111/j.1748-5827.2012.01251.x .
2012 Muñana,K.R.,Nettifee-Osborne,J.A.,Bergman,R.L.,Mealey,K.L.: :
Association between ABCB1 genotype and seizure outcome in Collies with epilepsy. J Vet Intern Med 26:1358-64, 2012.
Pubmed reference: 22998209 . DOI: 10.1111/j.1939-1676.2012.01006.x .
2012 Potschka,H.: :
Animal models of drug-resistant epilepsy. Epileptic Disord 14:226-34, 2012.
Pubmed reference: 22947487 . DOI: 10.1684/epd.2012.0532 .
2012 Seppälä,E.H.,Koskinen,L.L.,Gulløv,C.H.,Jokinen,P.,Karlskov-Mortensen,P.,Bergamasco,L.,BaranowskaKörberg,I.,Cizinauskas,S.,Oberbauer,A.M.,Berendt,M.,Fredholm,M.,Lohi,H.: :
Identification of a novel idiopathic epilepsy locus in Belgian Shepherd dogs. PLoS One 7:e33549, 2012.
Pubmed reference: 22457775 . DOI: 10.1371/journal.pone.0033549 .
2012 Stalin,K.: :
Investigating epilepsy in dogs. Vet Rec 170:333-4, 2012.
Pubmed reference: 22467822 . DOI: 10.1136/vr.e2340 .
2011 Alves,L.,Hülsmeyer,V.,Jaggy,A.,Fischer,A.,Leeb,T.,Drögemüller,M.: :
Polymorphisms in the ABCB1 gene in phenobarbital responsive and resistant idiopathic epileptic Border Collies. J Vet Intern Med 25:484-9, 2011.
Pubmed reference: 21488961 . DOI: 10.1111/j.1939-1676.2011.0718.x .
2011 Brauer,C.,Kästner,S.B.,Rohn,K.,Schenk,H.C.,Tünsmeyer,J.,Tipold,A.: :
Electroencephalographic recordings in dogs suffering from idiopathic and symptomatic epilepsy: Diagnostic value of interictal short time EEG protocols supplemented by two activation techniques. Vet J :, 2011.
Pubmed reference: 22099183 . DOI: 10.1016/j.tvjl.2011.10.006 .
2011 Browand-Stainback,L.,Levesque,D.,McBee,M.: :
Canine and feline epileptic seizures and the lunar cycle: 2,507 seizures (2000-2008). J Am Anim Hosp Assoc 47:324-8, 2011.
Pubmed reference: 21852516 . DOI: 10.5326/JAAHA-MS-5591 .
2011 Ekenstedt,K.J.,Patterson,E.E.,Minor,K.M.,Mickelson,J.R.: :
Candidate genes for idiopathic epilepsy in four dog breeds. BMC Genet 12:38, 2011.
Pubmed reference: 21518446 . DOI: 10.1186/1471-2156-12-38 .
2011 Gulløv,C.H.,Toft,N.,Baadsager,M.M.,Berendt,M.: :
Epilepsy in the Petit Basset Griffon Vendeen: prevalence, semiology, and clinical phenotype. J Vet Intern Med 25:1372-8, 2011.
Pubmed reference: 22092630 . DOI: 10.1111/j.1939-1676.2011.00791.x .
2011 Leppik,I.E.,Patterson,E.N.,Coles,L.D.,Craft,E.M.,Cloyd,J.C.: :
Canine status epilepticus: A translational platform for human therapeutic trials. Epilepsia :31-4, 2011.
Pubmed reference: 21967357 . DOI: 10.1111/j.1528-1167.2011.03231.x .
2011 Seppälä,E.H.,Jokinen,T.S.,Fukata,M.,Fukata,Y.,Webster,M.T.,Karlsson,E.K.,Kilpinen,S.K.,Steffen,F.,Dietschi,E.,Leeb,T.,Eklund,R.,Zhao,X.,Rilstone,J.J.,Lindblad-Toh,K.,Minassian,B.A.,Lohi,H.: :
LGI2 truncation causes a remitting focal epilepsy in dogs. PLoS Genet 7:e1002194, 2011.
Pubmed reference: 21829378 . DOI: 10.1371/journal.pgen.1002194 .
2011 Short,A.D.,Dunne,A.,Lohi,H.,Boulton,S.,Carter,S.D.,Timofte,D.,Ollier,W.E.: :
Characteristics of epileptic episodes in UK dog breeds: an epidemiological approach. Vet Rec 169:48, 2011.
Pubmed reference: 21709047 . DOI: 10.1136/vr.d1901 .
2011 Weissl,J.,Hülsmeyer,V.,Brauer,C.,Tipold,A.,Koskinen,L.L.,Kyöstilä,K.,Lohi,H.,Sauter-Louis,C.,Wolf,M.,Fischer,A.: :
Disease progression and treatment response of idiopathic epilepsy in Australian Shepherd dogs. J Vet Intern Med 26:116-25, 2011.
Pubmed reference: 22182230 . DOI: 10.1111/j.1939-1676.2011.00853.x .
2010 Hülsmeyer,V.,Zimmermann,R.,Brauer,C.,Sauter-Louis,C.,Fischer,A.: :
Epilepsy in Border Collies: clinical manifestation, outcome, and mode of inheritance. J Vet Intern Med 24:171-8, 2010.
Pubmed reference: 20391637 .
2010 Oberbauer,AM.,Belanger,JM.,Grossman,DI.,Regan,KR.,Famula,TR.: :
Genome-wide linkage scan for loci associated with epilepsy in Belgian shepherd dogs. BMC Genet 11:35, 2010.
Pubmed reference: 20441595 . DOI: 10.1186/1471-2156-11-35 .
2010 Thomas,WB.: :
Idiopathic epilepsy in dogs and cats. Vet Clin North Am Small Anim Pract 40:161-79, 2010.
Pubmed reference: 19942062 . DOI: 10.1016/j.cvsm.2009.09.004 .
2009 Berendt,M.,Gulløv,C.H.,Fredholm,M.: :
Focal epilepsy in the Belgian shepherd: evidence for simple Mendelian inheritance. J Small Anim Pract 50:655-61, 2009.
Pubmed reference: 19954442 . DOI: 10.1111/j.1748-5827.2009.00849.x .
2009 Scorza,FA.,Cavalheiro,EA.,Arida,RM.,Terra,VC.,Scorza,CA.,Ribeiro,MO.,Cysneiros,RM.: :
Positive impact of omega-3 fatty acid supplementation in a dog with drug-resistant epilepsy: a case study. Epilepsy Behav 15:527-8, 2009.
Pubmed reference: 19541544 . DOI: 10.1016/j.yebeh.2009.05.013 .
2009 Zimmermann,R.,Hülsmeyer,V.I.,Sauter-Louis,C.,Fischer,A.: :
Status epilepticus and epileptic seizures in dogs. J Vet Intern Med 23:970-6, 2009.
Pubmed reference: 19737178 . DOI: 10.1111/j.1939-1676.2009.0368.x .
2008 Berendt,M.,Gulløv,C.H.,Christensen,S.L.,Gudmundsdottir,H.,Gredal,H.,Fredholm,M.,Alban,L.: :
Prevalence and characteristics of epilepsy in the Belgian shepherd variants Groenendael and Tervueren born in Denmark 1995-2004. Acta Vet Scand 50:51, 2008.
Pubmed reference: 19102738 . DOI: 10.1186/1751-0147-50-51 .
2007 Licht,BG.,Lin,S.,Luo,Y.,Hyson,LL.,Licht,MH.,Harper,KM.,Sullivan,SA.,Fernandez,SA.,Johnston,EV.: :
Clinical characteristics and mode of inheritance of familial focal seizures in Standard Poodles. J Am Vet Med Assoc 231:1520-8, 2007.
Pubmed reference: 18020993 . DOI: 10.2460/javma.231.10.1520 .
2006 Casal,ML.,Munuve,RM.,Janis,MA.,Werner,P.,Henthorn,PS.: :
Epilepsy in Irish Wolfhounds. J Vet Intern Med 20:131-5, 2006.
Pubmed reference: 16496932 .
2006 Chandler,K.: :
Canine epilepsy: what can we learn from human seizure disorders? Vet J 172:207-17, 2006.
Pubmed reference: 16154785 . DOI: 10.1016/j.tvjl.2005.07.001 .
2006 Lass,P.,Teodorczyk,J.,Krzemiński,M.: :
Regional cerebral blood flow abnormalities in an epileptic boxer dog. Nucl Med Rev Cent East Eur 9:81, 2006.
Pubmed reference: 16791812 .
2005 Govendir,M.,Perkins,M.,Malik,R.: :
Improving seizure control in dogs with refractory epilepsy using gabapentin as an adjunctive agent. Aust Vet J 83:602-8, 2005.
Pubmed reference: 16255282 .
2005 Patterson,E.E.,Armstrong,P.J.,O'Brien,D.P.,Roberts,M.C.,Johnson,G.S.,Mickelson,J.R.: :
Clinical description and mode of inheritance of idiopathic epilepsy in English springer spaniels. J Am Vet Med Assoc 226:54-8, 2005.
Pubmed reference: 15646572 . DOI: 10.2460/javma.2005.226.54 .
2005 Volk,H.,Chandler,K.,Cappello,R.,Cherubini,GB.: :
Molecular basis of canine epilepsies. Vet Rec 157:752, 2005.
Pubmed reference: 16326975 .
2004 Berendt,M.,Gredal,H.,Alving,J.: :
Characteristics and phenomenology of epileptic partial seizures in dogs: similarities with human seizure semiology. Epilepsy Res 61:167-73, 2004.
Pubmed reference: 15451018 . DOI: 10.1016/j.eplepsyres.2004.07.009 .
2004 Gaskill,CL.,Hoffmann,WE.,Cribb,AE.: :
Serum alkaline phosphatase isoenzyme profiles in phenobarbital-treated epileptic dogs. Vet Clin Pathol 33:215-22, 2004.
Pubmed reference: 15570558 .
2004 vanHagen,MA.,Janss,LL.,vandenBroek,J.,Knol,BW.: :
The use of a genetic-counselling program by Dutch breeders for four hereditary health problems in boxer dogs. Prev Vet Med 63:39-50, 2004.
Pubmed reference: 15099715 . DOI: 10.1016/j.prevetmed.2004.01.007 .
2003 Oberbauer,AM.,Grossman,DI.,Irion,DN.,Schaffer,AL.,Eggleston,ML.,Famula,TR.: :
The genetics of epilepsy in the Belgian tervuren and sheepdog. J Hered 94:57-63, 2003.
Pubmed reference: 12692163 .
2003 Patterson,E.E.,Mickelson,J.R.,Da,Y.,Roberts,M.C.,McVey,A.S.,O'Brien,D.P.,Johnson,G.S.,Armstrong,P.J.: :
Clinical characteristics and inheritance of idiopathic epilepsy in Vizslas Journal of Veterinary Internal Medicine 17:319-25, 2003.
Pubmed reference: 12774973 .
2002 Buckmaster,P.S.,Smith,M.O.,Buckmaster,C.L.,LeCouteur,R.A.,Dudek,F.E.: :
Absence of temporal lobe epilepsy pathology in dogs with medically intractable epilepsy Journal of Veterinary Internal Medicine 16:95-99, 2002.
Pubmed reference: 11822812 .
2002 Dunnett,M.,Littleford,A.,Lees,P.: :
Phenobarbitone concentrations in the hair, saliva and plasma of eight epileptic dogs Veterinary Record 150:718-724, 2002.
Pubmed reference: 12081307 .
2002 Hasegawa,D.,Fujita,M.,Nakamura,S.,Takahashi,K.,Orima,H.: :
Electrocorticographic and histological findings in a Shetland sheepdog with intractable epilepsy Journal of Veterinary Medical Science 64:277-279, 2002.
Pubmed reference: 11999451 .
2002 Morita,T.,Shimada,A.,Takeuchi,T.,Hikasa,Y.,Sawada,M.,Ohiwa,S.,Takahashi,M.,Kubo,N.,Shibahara,T.,Miyata,H.,Ohama,E.: :
Cliniconeuropathologic findings of familial frontal lobe epilepsy in Shetland sheepdogs Canadian Journal of Veterinary Research - Revue Canadienne de Recherche Veterinaire 66:35-41, 2002.
Pubmed reference: 11858647 .
2002 Munana,K.R.,Vitek,S.M.,Tarver,W.B.,Saito,M.,Skeen,T.M.,Sharp,N.J.H.,Olby,N.J.,Haglund,M.M.: :
Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs Journal of the American Veterinary Medical Association 221:977-983, 2002.
Pubmed reference: 12369700 .
2000 Anon.: :
Effect of timing of blood collection on serum phenobarbital concentrations in dogs with epilepsy (vol 217, pg 200, 2000) Journal of the American Veterinary Medical Association 217:508, 2000.
2000 Famula,T.R.,Oberbauer,A.M.: :
Segregation analysis of epilepsy in the Belgian tervueren dog Veterinary Record 147:218-221, 2000.
Pubmed reference: 10994924 .
2000 Gaskill,C.L.,Cribb,A.E.: :
Pancreatitis associated with potassium bromide/phenobarbital combination therapy in epileptic dogs Canadian Veterinary Journal - Revue Veterinaire Canadienne 41:555-558, 2000.
2000 Thomas,W.B.: :
Idiopathic epilepsy in dogs Veterinary Clinics of North America - Small Animal Practice 30:183-206, 2000.
1999 Berendt,M.,Gram,L.: :
Epilepsy and seizure classification in 63 dogs: A reappraisal of veterinary epilepsy terminology Journal of Veterinary Internal Medicine 13:14-20, 1999.
Pubmed reference: 10052058 .
1999 Berendt,M.,Hogenhaven,H.,Flagstad,A.,Dam,M.: :
Electroencephalography in dogs with epilepsy: similarities between human and canine findings Acta Neurologica Scandinavica 99:276-283, 1999.
Pubmed reference: 10348156 .
1999 Dowling,P.M.: :
Update on therapy of canine epilepsy Canadian Veterinary Journal - Revue Veterinaire Canadienne 40:595-598, 1999.
1999 Hall,S.J.G.: :
Canine idiopathic epilepsy Journal of Small Animal Practice 40:192, 1999.
Pubmed reference: 10340251 .
1999 Hilsenroth,R.: :
Pharmacological-control of canine epilepsy Canine Practice 24:24, 1999.
1999 Jaggy,A.: :
Canine idiopathic epilepsy - Response Journal of Small Animal Practice 40:192, 1999.
1999 Kantrowitz,L.B.,Peterson,M.E.,Trepanier,L.A.,Melian,C.,Nichols,R.: :
Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants Journal of the American Veterinary Medical Association 214:1804-1808, 1999.
Pubmed reference: 10382022 .
1999 Kathmann,I.,Jaggy,A.,Busato,A.,Bartschi,M.,Gaillard,C.: :
Clinical and genetic investigations of idiopathic epilepsy in the Bernese mountain dog Journal of Small Animal Practice 40:319-325, 1999.
Pubmed reference: 10444751 .
1999 Lord,L.K.,Podell,M.: :
Owner perception of the care of long-term phenobarbital-treated epileptic dogs Journal of Small Animal Practice 40:11-15, 1999.
Pubmed reference: 10092036 .
1999 Podell,M.,Hadjiconstantinou,M.: :
Low concentrations of cerebrospinal fluid GABA correlate to a reduced response to phenobarbital therapy in primary canine epilepsy Journal of Veterinary Internal Medicine 13:89-94, 1999.
Pubmed reference: 10225597 .
1999 Rambeck,B.,May,T.W.,Jurgens,U.,Schwartz-Porsche,D.: :
Concentrations of phenobarbital in epileptic dogs on phenobarbital or primidone therapy [German] Kleintierpraxis 44:345-+, 1999.
1999 Vaughan-Scott,T.,Taylor,J.H.: :
Drug choice and therapeutic drug monitoring in the management of canine primary epilepsy Journal of the South African Veterinary Medical Association 70:172-176, 1999.
1998 Famula,T.R.,Oberbauer,A.M.: :
Reducing the incidence of epileptic seizures in the Belgian Tervuren through selection Preventive Veterinary Medicine 33:251-259, 1998.
Pubmed reference: 9500179 .
1998 Gyula,K.: :
Idiopathic epilepsy in 125 dogs - a long-term study - clinical and electroencephalic findings - additions - remarks [Hungarian] Magyar Allatorvosok Lapja 120:270-272, 1998.
1998 Jaggy,A.,Bernardini,M.: :
Idiopathic epilepsy in 125 dogs - a long-term study - clinical and electroencephalic findings [Hungarian] Magyar Allatorvosok Lapja 120:268-270, 1998.
1998 Jaggy,A.,Bernardini,M.: :
Idiopathic epilepsy in 125 dogs - a long-term study - clinical and electroencephalographic findings Journal of Small Animal Practice 39:23-29, 1998.
Pubmed reference: 9494931 .
1998 Jaggy,A.,Faissler,D.,Gaillard,C.,Srenk,P.,Graber,H.: :
Genetic aspects of idiopathic epilepsy in labrador retrievers Journal of Small Animal Practice 39:275-280, 1998.
Pubmed reference: 9673903 .
1997 Famula,T.R.,Oberbauer,A.M.,Brown,K.N.: :
Heritability of epileptic seizures in the Belgian Tervueren Journal of Small Animal Practice 38:349-352, 1997.
Pubmed reference: 9282341 .
1997 Heynold,Y.,Faissler,D.,Steffen,F.,Jaggy,A.: :
Clinical, epidemiological and treatment results of idiopathic epilepsy in 54 Labrador retrievers - a long-term study Journal of Small Animal Practice 38:7-14, 1997.
Pubmed reference: 9121134 .
1997 Obrien,D.P.,Simpson,S.T.,Longshore,R.C.,Kroll,R.A.,Goetze,L.: :
Nimodipine for treatment of idiopathic epilepsy in dogs Journal of the American Veterinary Medical Association 210:1298-1301, 1997.
Pubmed reference: 9143533 .
1997 Podell,M.,Hadjiconstantinou,M.: :
Cerebrospinal fluid gamma-aminobutyric acid and glutamate values in dogs with epilepsy American Journal of Veterinary Research 58:451-456, 1997.
Pubmed reference: 9140549 .
1996 Boothe,D.M.,Simpson,G.,Foster,T.: :
Effects of serum separation tubes on serum benzodiazepine and phenobarbital concentrations in clinically normal and epileptic dogs American Journal of Veterinary Research 57:1299-1303, 1996.
Pubmed reference: 8874722 .
1996 Hall,S.J.G.,Wallace,M.E.: :
Canine epilepsy - a genetic counselling programme for Keeshonds Veterinary Record 138:358-360, 1996.
Pubmed reference: 8737262 .
1996 Jaggy,A.,Heynold,Y.: :
Idiopathic epilepsy in the dog [German] Schweizer Archiv fur Tierheilkunde 138:523-531, 1996.
Pubmed reference: 9026909 .
1996 Srenk,P.,Jaggy,A.: :
Interictal electroencephalographic findings in a family of golden retrievers with idiopathic epilepsy Journal of Small Animal Practice 37:317-321, 1996.
Pubmed reference: 8840251 .
1995 Chauvet,A.E.,Feldman,E.C.,Kass,P.H.: :
Effects of phenobarbital administration on results of serum biochemical analyses and adrenocortical function tests in epileptic dogs Journal of the American Veterinary Medical Association 207:1305 ff., 1995.
1995 Steffen,F.,Jaggy,A.: :
Seizures in dogs .3. Intracerebral causes, idiopathic epilepsy Praktische Tierarzt 76:304, 1995.
1993 Herkes,G.K.,Eadie,M.J.,Sharbrough,F.,Moyer,T.: :
Patterns of seizure occurrence in catamenial epilepsy. Epilepsy Res 15:47-52, 1993.
Pubmed reference: 8325277 .
1993 Shell,L.G.,Dyer,K.R.,Parent,J.M.,Steinberg,S.H.: :
How Do I Treat - Maintenance Anticonvulsant Therapy for Idiopathic Epilepsy in Dogs Progress in Veterinary Neurology 4:143-144, 1993.
1988 Cunningham,J.G.,Farnbach,G.C.: :
Inheritance and idiopathic canine epilepsy Journal of the American Animal Hospital Association 24:421-424, 1988.
1974 Falco,M.J.,Barker,J.,Wallace,M.E.: :
The genetics of epilepsy in the British Alsatian Journal of Small Animal Practice 15:685-692, 1974.
Pubmed reference: 4449202 .
1971 Bielfelt,S.W.,Redman,R.D.,McClellon,R.D.: :
Sire-sex related differences in rates of epileptiform seizures in a purebred Beagle dog colony American Journal of Veterinary Research 32:2039-2049, 1971.
Pubmed reference: 5131425 .
1971 Lawler,D.C.: :
Epilepsy in dogs New Zealand Veterinary Journal 19:53 only, 1971.
1965 Croft,P.G.: :
Fits in dogs: a survey of 260 cases Veterinary Record 77:438-445, 1965.
Pubmed reference: 14331408 .
1962 Croft,P.G.: :
The EEG as an aid to diagnosis of nervous disease in the dog and cat Journal of Small Animal Practice 3:205-213, 1962.
1959 Eberhart,G.W.: :
Epilepsy in the dog Proceedings of the Ninth Gaines Veterinary Symposium, Kankakee :18-20, 1959.
1951 Eberhart,G.W.: :
Epilepsy in the dog Proceedings of the First Gaines Veterinary Symposium :20, 1951.