The detail information of Spinal dysraphism
OMIA Basic Information

Possible human homologues (MIM numbers): -

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Year key mutation first reported: 2013

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB252 Weimaraner 63.5-68.6 cm (male), 58.4-63.5 cm (female) 31.8-40.8 kg (male), 24.9-34 kg (female) Germany
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2013 Safra,N.,Bassuk,A.G.,Ferguson,P.J.,Aguilar,M.,Coulson,R.L.,Thomas,N.,Hitchens,P.L.,Dickinson,P.J.,Vernau,K.M.,Wolf,Z.T.,Bannasch,D.L.: :
Genome-wide association mapping in dogs enables identification of the homeobox gene, NKX2-8, as a genetic component of neural tube defects in humans. PLoS Genet 9:e1003646, 2013.
Pubmed reference: 23874236 . DOI: 10.1371/journal.pgen.1003646 .
2012 Allett,B.,Broome,M.R.,Hager,D.: :
MRI of a split cord malformation in a German shepherd dog. J Am Anim Hosp Assoc 48:344-51, 2012.
Pubmed reference: 22843830 . DOI: 10.5326/JAAHA-MS-5780 .
1995 Ruberte,J.,Añor,S.,Carretero,A.,Vilafranca,M.,Navarro,M.,Mascort,J.,Pumarola,M.: :
Malformations of the vertebral bodies and the ribs associated to spinal dysraphism without spina bifida in a Pekingese dog. Zentralbl Veterinarmed A 42:307-13, 1995.
Pubmed reference: 8578905 .
1992 Bailey,C.S.,Morgan,J.P.: :
Congenital spinal malformations. Vet Clin North Am Small Anim Pract 22:985-1015, 1992.
Pubmed reference: 1641930 .
1991 Vandenbroek,A.H.M.,Else,R.W.,Abercromby,R.,France,M.: :
Spinal Dysraphism in the Weimaraner Journal of Small Animal Practice 32:258-260, 1991.
1982 Engel,H.N.,Draper,D.D.: :
Comparative prenatal development of the spinal cord in normal and dysraphic dogs: embryonic stage. Am J Vet Res 43:1729-34, 1982.
Pubmed reference: 6756221 .
1982 Engel,H.N.,Draper,D.D.: :
Comparative prenatal development of the spinal cord in normal and dysraphic dogs: fetal stage. Am J Vet Res 43:1735-43, 1982.
Pubmed reference: 6756222 .
1976 Draper,D.D.,Kluge,J.P.,Millerw,J.: :
Clinical and pathological aspects of spinal dysraphism in dogs. Thessaloniki 1:134-137, 1976.
1974 Neufeld,J.L.,Little,P.B.: :
Spinal dysraphism in a Dalmatian dog. Can Vet J 15:335-6, 1974.
Pubmed reference: 4434313 .
1973 Klaus,B.: :
[Picture report. Spinal dysraphism in a German shepherd]. Berl Munch Tierarztl Wochenschr 86:95, 1973.
Pubmed reference: 4732250 .
1972 Confer,A.W.,Ward,B.C.: :
Spinal dysraphism: a congenital myelodysplasia in the Weimaraner Journal of the American Veterinary Medical Association 160:1423-1426, 1972.
Pubmed reference: 5023160 .
1967 Geib,L.W.,Bistner,S.I.: :
Spinal cord dysraphism in a dog. J Am Vet Med Assoc 150:618-20, 1967.
Pubmed reference: 5339905 .
1965 Foster,S.J.: :
A case of sternal dysraphism and two cases of suspected congenital diaphragmatic hernia in the dog. Vet Rec 77:1112-4, 1965.
Pubmed reference: 5318050 .
1965 McGrath,J.T.: :
Spinal dysraphism in the dog, with comments on syringomylia Pathologia Veterinaria 2:1-36 (Supplement), 1965.
Pubmed reference: 5893238 .