The detail information of Muscular dystrophy
Basic Information
Disease Ontology ID: DDTO:0000008
Abbreviated Name: MD
Disease Description: A congenital and often inherited form of generalized muscle dysfunction which causes signs such as poor growth, weakness, abnormal gait, dificulty eating and swallowing, and muscle atrophy.
Inherit Mode: -
Disease Symptom: Dogs with muscular dystrophy begin to show clinical signs at about 8 weeks of age. Initially they have muscular weakness, exercise intolerance and a stiff gait. Within a few weeks muscle atrophy spreads and becomes apparent. These initial signs are followed by generalized weakness, enlargement of the tongue, and difficulty swallowing. Affected puppy or dog has problems moving his tongue, drools excessively, retains food in his mouth, has difficulty breathing, muscle spasms of the neck that last 10 to 30 seconds, and increased exercise intolerance. The dog is able to chew but drops food during swallowing due to inappropriate tongue movement. Likewise, he is not able to drink normally but has to extend his head and neck to swallow water.
Disease Cause: -
Disease Diagnose: Muscle biopsy evaluation is critical to the diagnosis of muscle diseases in young puppies. Progressive muscle diseases affecting young puppies can be noninflammatory and include dystrophies, metabolic and mitochondrial disorders; or they can be inflammatory secondary to immune-mediated disease or infection with Toxoplasma gondii or Neospora caninum. An accurate diagnosis is critical for prognosis, for determination of appropriate therapy if available, and for elimination of genetic diseases from breeding populations.
Treat Method: Unfortunately at this time there is neither a cure nor a specific therapy for muscular dystrophy of any genetic origin. Anabolic supplements and growth factors may help slow the progression of the disease, but their efficacy is unproven, and they are expensive and can quickly become cost prohibitive for some owners. A stem cell breakthrough could lead to a treatment for muscular dystrophy, research has revealed. Scientists found transplanting stem cells into dogs with a version of the disease markedly improved their signs. However, the researchers need to find out why not all dogs respond positively.Life expectancy depends on the severity of clinical signs. Death may occur within the first few days in the case of severe complications, or dogs can survive for up to several years. Like people, dogs with muscular dystrophy often develop a heart muscle disease, and their heart disease is often what eventually leads to death.
Breeder Advice: -
Disease Description Source: Link
Associated Diseases
| Disease Name | Other Name | Mode of inheritance | Link ID | Possible OMIM ID | Gene |
|---|---|---|---|---|---|
| Muscular dystrophy | - | - | - | ||
| Muscular dystrophy, Becker type | - | - | - | ||
| Muscular dystrophy, Duchenne type | X-linked muscular dystrophy; Dystrophin-deficient muscular dystrophy | X-linked recessive | - | ||
| Muscular dystrophy, limb-girdle, type R6 (LGMDR6) | - | - | - | ||
| Muscular dystrophy, Ullrich type | Muscular Dystrophy | Autosomal Recessive | - | ||
| Muscular dystrophy, COL6A3-related | - | - | - | ||
| Muscular dystrophy, limb-girdle, type R3 (LGMDR3) | - | Autosomal Recessive | - | ||
| Congenital muscular dystrophy, LAMA2-related | - | - | - | - |
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | Breed Source |
|---|---|---|---|---|---|
| CB11 | American Staffordshire Terrier | Confident, Smart, Good-natured | 18-19 inches (male), 17-18 inches (female) | 55-70 pounds (male), 40-55 pounds (female) | United States |
| CB31 | Belgian Tervuren | Smart, self-assured, very trainable; affectionate and possessive with loved ones | 61-66 cm (male), 55.9-61 cm (female) | 24.9-34 kg (male), 20.4-27.2 kg (female) | Belgium |
| CB76 | Cirneco dell'Etna | Affectionate, Friendly, Independent | 18-19.5 inches (male), 16.5-18 inches (female) | 22-26 pounds (male), 17-22 pounds (female) | Italy |
| CB117 | Gordon Setter | Bold, confident, and resolute afield; sweetly affectionate by the fireside | 61-68.6 cm (male), 58.4-66 cm (female) | 24.9-36.3 kg (male), 20.4-31.8 kg (female) | United Kingdom (Scotland) |
| CB120 | Great Pyrenees | Calm, patient, smart; strong-willed yet affectionate | 68.6-81.3 cm (male), 63.5-73.7 cm (female) | 45.4 kg & up (male), 38.6 kg & up (female) | France, Spain |
| CB133 | Irish Water Spaniel | Alert and inquisitive; hardworking and brave in the field, playful and affectionate at home | 55.9-61 cm (male), 53.3-58.4 cm (female) | 24.9-30.8 kg (male), 20.4-26.3 kg (female) | Ireland |
| CB148 | Lagotto Romagnolo(Romagna Water Dog) | Easygoing, affectionate, and eager to please | 43.2-48.3 cm (male), 40.6-45.7 cm (female) | 12.9-15.9 kg (male), 10.9-14.1 kg (female) | Italy |
Associated Disease Variants from OMIA
Gene Differential Expression
References
| 2021 |
Kupatt,C.,Windisch,A.,Moretti,A.,Wolf,E.,Wurst,W.,Walter,M.C.: :
Genome editing for Duchenne muscular dystrophy: a glimpse of the future? Gene Ther :, 2021. Pubmed reference: 33531685 . DOI: 10.1038/s41434-021-00222-4 . |
| 2021 |
Nitahara-Kasahara,Y.,Kuraoka,M.,Guillermo,P.H.,Hayashita-Kinoh,H.,Maruoka,Y.,Nakamura-Takahasi,A.,Kimura,K.,Takeda,S.,Okada,T.: :
Dental pulp stem cells can improve muscle dysfunction in animal models of Duchenne muscular dystrophy. Stem Cell Res Ther 12:78, 2021. Pubmed reference: 33494794 . DOI: 10.1186/s13287-020-02099-3 . |
| 2021 |
Tone,Y.,Mamchaoui,K.,Tsoumpra,M.K.,Hashimoto,Y.,Terada,R.,Maruyama,R.,Gait,M.J.,Arzumanov,A.A.,McClorey,G.,Imamura,M.,Takeda,S.,Yokota,T.,Wood,M.J.A.,Mouly,V.,Aoki,Y.: :
Immortalized canine dystrophic myoblast cell lines for development of peptide-conjugated splice-switching oligonucleotides. Nucleic Acid Ther 31:172-181, 2021. Pubmed reference: 33567244 . DOI: 10.1089/nat.2020.0907 . |
| 2021 |
Mickelson,J.R.,Minor,K.M.,Guo,L.T.,Friedenberg,S.G.,Cullen,J.N.,Ciavarella,A.,Hambrook,L.E.,Brenner,K.M.,Helmond,S.E.,Marks,S.L.,Shelton,G.D.: :
Sarcoglycan A mutation in miniature dachshund dogs causes limb-girdle muscular dystrophy 2D. Skelet Muscle 11:2, 2021. Pubmed reference: 33407862 . DOI: 10.1186/s13395-020-00257-y . |
| 2020 |
Salvadori,C.,Vattemi,G.,Guglielmi,V.,Marini,M.,Tomelleri,G.,Cantile,C.: :
Protein expression of canine and feline muscular dystrophies. Top Companion Anim Med :100500, 2020. Pubmed reference: 33249241 . DOI: 10.1016/j.tcam.2020.100500 . |
| 2020 |
Barthélémy,I.,Calmels,N.,Weiss,R.B.,Tiret,L.,Vulin,A.,Wein,N.,Peccate,C.,Drougard,C.,Beroud,C.,Deburgrave,N.,Thibaud,J.L.,Escriou,C.,Punzón,I.,Garcia,L.,Kaplan,J.C.,Flanigan,K.M.,Leturcq,F.,Blot,S.: :
X-linked muscular dystrophy in a Labrador Retriever strain: phenotypic and molecular characterisation. Skelet Muscle 10:23, 2020. Pubmed reference: 32767978 . DOI: 10.1186/s13395-020-00239-0 . |
| 2020 |
Brinkmeyer-Langford,C.,Chu,C.,Balog-Alvarez,C.,Yu,X.,Cai,J.J.,Nabity,M.,Kornegay,J.N.: :
Correction: Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. PLoS One 15:e0236916, 2020. Pubmed reference: 32702009 . DOI: 10.1371/journal.pone.0236916 . |
| 2020 |
Brunetti,B.,Muscatello,L.V.,Letko,A.,Papa,V.,Cenacchi,G.,Grillini,M.,Murgiano,L.,Jagannathan,V.,Drögemüller,C.: :
X-Linked Duchenne-Type Muscular Dystrophy in Jack Russell Terrier Associated with a Partial Deletion of the Canine <i>DMD</i> Gene. Genes (Basel) 11:, 2020. Pubmed reference: 33049940 . DOI: 10.3390/genes11101175 . |
| 2020 |
Story,B.D.,Miller,M.E.,Bradbury,A.M.,Million,E.D.,Duan,D.,Taghian,T.,Faissler,D.,Fernau,D.,Beecy,S.J.,Gray-Edwards,H.L.: :
Canine models of inherited musculoskeletal and neurodegenerative diseases. Front Vet Sci 7:80, 2020. Pubmed reference: 32219101 . DOI: 10.3389/fvets.2020.00080 . |
| 2020 |
Switonski,M.: :
Impact of gene therapy for canine monogenic diseases on the progress of preclinical studies. J Appl Genet :, 2020. Pubmed reference: 32189222 . DOI: 10.1007/s13353-020-00554-8 . |
| 2020 |
Brands,J.,Steffen,F.,Spennes,J.,Leeb,T.,Bilzer,T.: :
COL6A1 related muscular dystrophy in Landseer dogs - a canine model for Ullrich congenital muscular dystrophy. Muscle Nerve :, 2020. Pubmed reference: 33382107 . DOI: 10.1002/mus.27162 . |
| 2020 |
Bolduc,V.,Minor,K.M.,Hu,Y.,Kaur,R.,Friedenberg,S.G.,VanBuren,S.,Guo,L.T.,Glennon,J.C.,Marioni-Henry,K.,Mickelson,J.R.,Bönnemann,C.G.,Shelton,G.D.: :
Pathogenic variants in COL6A3 cause Ullrich-like congenital muscular dystrophy in young Labrador Retriever dogs. Neuromuscul Disord :, 2020. Pubmed reference: 32439203 . DOI: 10.1016/j.nmd.2020.03.005 . |
| 2019 |
Nghiem,P.P.,Kornegay,J.N.: :
Gene therapies in canine models for Duchenne muscular dystrophy. Hum Genet 138:483-489, 2019. Pubmed reference: 30734120 . DOI: 10.1007/s00439-019-01976-z . |
| 2019 |
Wasala,N.B.,Hakim,C.H.,Chen,S.J.,Yang,N.N.,Duan,D.: :
Questions Answered and Unanswered by the First CRISPR Editing Study in a Canine Model of Duchenne Muscular Dystrophy. Hum Gene Ther 30:535-543, 2019. Pubmed reference: 30648435 . DOI: 10.1089/hum.2018.243 . |
| 2018 |
Amoasii,L.,Hildyard,J.C.W.,Li,H.,Sanchez-Ortiz,E.,Mireault,A.,Caballero,D.,Harron,R.,Stathopoulou,T.R.,Massey,C.,Shelton,J.M.,Bassel-Duby,R.,Piercy,R.J.,Olson,E.N.: :
Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Science :, 2018. Pubmed reference: 30166439 . DOI: 10.1126/science.aau1549 . |
| 2018 |
Brinkmeyer-Langford,C.,Chu,C.,Balog-Alvarez,C.,Yu,X.,Cai,J.J.,Nabity,M.,Kornegay,J.N.: :
Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. PLoS One 13:e0194485, 2018. Pubmed reference: 29554127 . DOI: 10.1371/journal.pone.0194485 . |
| 2018 |
Cohen,J.: :
In dogs, CRISPR fixes a muscular dystrophy. Science 361:835, 2018. Pubmed reference: 30166469 . DOI: 10.1126/science.361.6405.835 . |
| 2018 |
Eresen,A.,Alic,L.,Kornegay,J.,Ji,J.X.: :
Assessment of disease severity in a Canine Model of Duchenne Muscular Dystrophy: Classification of Quantitative MRI. Conf Proc IEEE Eng Med Biol Soc 2018:648-651, 2018. Pubmed reference: 30440480 . DOI: 10.1109/EMBC.2018.8512303 . |
| 2018 |
Maruyama,R.,Aoki,Y.,Takeda,S.,Yokota,T.: :
In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs. Methods Mol Biol 1828:365-379, 2018. Pubmed reference: 30171554 . DOI: 10.1007/978-1-4939-8651-4_23 . |
| 2018 |
MataLópez,S.,Hammond,J.J.,Rigsby,M.B.,Balog-Alvarez,C.J.,Kornegay,J.N.,Nghiem,P.P.: :
A novel canine model for Duchenne muscular dystrophy (DMD): single nucleotide deletion in DMD gene exon 20. Skelet Muscle 8:16, 2018. Pubmed reference: 29843823 . DOI: 10.1186/s13395-018-0162-1 . |
| 2018 |
Nakamura,A.,Aoki,Y.,Tsoumpra,M.,Yokota,T.,Takeda,S.: :
In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient. Methods Mol Biol 1828:151-163, 2018. Pubmed reference: 30171540 . DOI: 10.1007/978-1-4939-8651-4_9 . |
| 2018 |
Shrader,S.M.,Jung,S.,Denney,T.S.,Smith,B.F.: :
Characterization of Australian Labradoodle dystrophinopathy. Neuromuscul Disord 28:927-937, 2018. Pubmed reference: 30286978 . DOI: 10.1016/j.nmd.2018.08.008 . |
| 2018 |
Sánchez,L.,Beltrán,E.,deStefani,A.,Guo,L.T.,Shea,A.,Shelton,G.D.,DeRisio,L.,Burmeister,L.M.: :
Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs. PLoS One 13:e0193372, 2018. Pubmed reference: 29474464 . DOI: 10.1371/journal.pone.0193372 . |
| 2017 |
Kodippili,K.,Hakim,C.,Pan,X.,Yang,H.T.,YUe,Y.,Zhang,Y.,Shin,J.H.,Yang,N.N.,Duan,D.: :
Dual AAV gene therapy for Duchenne muscular dystrophy with a 7-kb mini-dystrophin gene in the canine model. Hum Gene Ther :, 2017. Pubmed reference: 28793798 . DOI: 10.1089/hum.2017.095 . |
| 2017 |
Kornegay,J.N.: :
The golden retriever model of Duchenne muscular dystrophy. Skelet Muscle 7:9, 2017. Pubmed reference: 28526070 . DOI: 10.1186/s13395-017-0124-z . |
| 2017 |
LeGuiner,C.,Servais,L.,Montus,M.,Larcher,T.,Fraysse,B.,Moullec,S.,Allais,M.,François,V.,Dutilleul,M.,Malerba,A.,Koo,T.,Thibaut,J.L.,Matot,B.,Devaux,M.,LeDuff,J.,Deschamps,J.Y.,Barthelemy,I.,Blot,S.,Testault,I.,Wahbi,K.,Ederhy,S.,Martin,S.,Veron,P.,Georger,C.,Athanasopoulos,T.,Masurier,C.,Mingozzi,F.,Carlier,P.,Gjata,B.,Hogrel,J.Y.,Adjali,O.,Mavilio,F.,Voit,T.,Moullier,P.,Dickson,G.: :
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy. Nat Commun 8:16105, 2017. Pubmed reference: 28742067 . DOI: 10.1038/ncomms16105 . |
| 2017 |
Maruyama,R.,Echigoya,Y.,Caluseriu,O.,Aoki,Y.,Takeda,S.,Yokota,T.: :
Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy. Methods Mol Biol 1565:201-213, 2017. Pubmed reference: 28364245 . DOI: 10.1007/978-1-4939-6817-6_17 . |
| 2017 |
Nghiem,P.P.,Bello,L.,Stoughton,W.B.,López,S.M.,Vidal,A.H.,Hernandez,B.V.,Hulbert,K.N.,Gourley,T.R.,Bettis,A.K.,Balog-Alvarez,C.J.,Heath-Barnett,H.,Kornegay,J.N.: :
Changes in Muscle Metabolism are Associated with Phenotypic Variability in Golden Retriever Muscular Dystrophy


. Yale J Biol Med 90:351-360, 2017. Pubmed reference: 28955176 . |
| 2017 |
VanBelzen,D.J.,Malik,A.S.,Henthorn,P.S.,Kornegay,J.N.,Stedman,H.H.: :
Mechanism of Deletion Removing All Dystrophin Exons in a Canine Model for DMD Implicates Concerted Evolution of X Chromosome Pseudogenes. Mol Ther Methods Clin Dev 4:62-71, 2017. Pubmed reference: 28344992 . DOI: 10.1016/j.omtm.2016.12.001 . |
| 2017 |
Wilson,K.,Faelan,C.,Patterson-Kane,J.C.,Rudmann,D.G.,Moore,S.A.,Frank,D.,Charleston,J.,Tinsley,J.,Young,G.D.,Milici,A.J.: :
Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification. Toxicol Pathol 45:961-976, 2017. Pubmed reference: 28974147 . DOI: 10.1177/0192623317734823 . |
| 2017 |
Cox,M.L.,Evans,J.M.,Davis,A.G.,Guo,L.T.,Levy,J.R.,Starr-Moss,A.N.,Salmela,E.,Hytönen,M.K.,Lohi,H.,Campbell,K.P.,Clark,L.A.,Shelton,G.D.: :
Exome sequencing reveals independent SGCD deletions causing limb girdle muscular dystrophy in Boston terriers. Skelet Muscle 7:15, 2017. Pubmed reference: 28702169 . DOI: 10.1186/s13395-017-0131-0 . |
| 2016 |
Acosta,A.R.,VanWie,E.,Stoughton,W.B.,Bettis,A.K.,Barnett,H.H.,LaBrie,N.R.,Balog-Alvarez,C.J.,Nghiem,P.P.,Cummings,K.J.,Kornegay,J.N.: :
Use of the six-minute walk test to characterize golden retriever muscular dystrophy. Neuromuscul Disord :, 2016. Pubmed reference: 27818009 . DOI: 10.1016/j.nmd.2016.09.024 . |
| 2016 |
Brinkmeyer-Langford,C.,Balog-Alvarez,C.,Cai,J.J.,Davis,B.W.,Kornegay,J.N.: :
Genome-wide association study to identify potential genetic modifiers in a canine model for Duchenne muscular dystrophy. BMC Genomics 17:665, 2016. Pubmed reference: 27549615 . DOI: 10.1186/s12864-016-2948-z . |
| 2016 |
Galindo,C.L.,Soslow,J.H.,Brinkmeyer-Langford,C.L.,Gupte,M.,Smith,H.M.,Sengsayadeth,S.,Sawyer,D.B.,Benson,D.W.,Kornegay,J.N.,Markham,L.W.: :
Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy. Pediatr Res 79:629-36, 2016. Pubmed reference: 26672735 . DOI: 10.1038/pr.2015.257 . |
| 2016 |
Gentil,C.,LeGuiner,C.,Falcone,S.,Hogrel,J.Y.,Peccate,C.,Lorain,S.,Benkhelifa-Ziyyat,S.,Guigand,L.,Montus,M.,Servais,L.,Voit,T.,Piétri-Rouxel,F.: :
Dystrophin Threshold Level Necessary for Normalization of Neuronal Nitric Oxide Synthase, Inducible Nitric Oxide Synthase, and Ryanodine Receptor-Calcium Release Channel Type 1 Nitrosylation in Golden Retriever Muscular Dystrophy Dystrophinopathy. Hum Gene Ther :, 2016. Pubmed reference: 27279388 . DOI: 10.1089/hum.2016.041 . |
| 2016 |
Kornegay,J.N.,Bogan,D.J.,Bogan,J.R.,Dow,J.L.,Wang,J.,Fan,Z.,Liu,N.,Warsing,L.C.,Grange,R.W.,Ahn,M.,Balog-Alvarez,C.J.,Cotten,S.W.,Willis,M.S.,Brinkmeyer-Langford,C.,Zhu,H.,Palandra,J.,Morris,C.A.,Styner,M.A.,Wagner,K.R.: :
Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures. Skelet Muscle 6:14, 2016. Pubmed reference: 27047655 . DOI: 10.1186/s13395-016-0085-7 . |
| 2016 |
MiskewNichols,B.,Aoki,Y.,Kuraoka,M.,Lee,J.J.,Takeda,S.,Yokota,T.: :
Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy. J Vis Exp :, 2016. Pubmed reference: 27285612 . DOI: 10.3791/53776 . |
| 2016 |
Nghiem,P.P.,Bello,L.,Balog-Alvarez,C.,MataLópez,S.,Bettis,A.,Barnett,H.,Hernandez,B.,Schatzberg,S.J.,Piercy,R.J.,Kornegay,J.N.: :
Whole genome sequencing reveals a 7 base-pair deletion in DMD exon 42 in a dog with muscular dystrophy Mammalian Genome :, 2016. Pubmed reference: 28028563 . DOI: 10.1007/s00335-016-9675-2 . |
| 2016 |
Sitzia,C.,Farini,A.,Jardim,L.,Razini,P.,Belicchi,M.,Cassinelli,L.,Villa,C.,Erratico,S.,Parolini,D.,Bella,P.,CarlosdaSilvaBizario,J.,Garcia,L.,DiasBaruffi,M.,Meregalli,M.,Torrente,Y.: :
Adaptive immune response impairs the efficacy of autologous transplantation of engineered stem cells in dystrophic dogs. Mol Ther :, 2016. Pubmed reference: 27506452 . DOI: 10.1038/mt.2016.163 . |
| 2016 |
Terrill,J.R.,Duong,M.N.,Turner,R.,LeGuiner,C.,Boyatzis,A.,Kettle,A.J.,Grounds,M.D.,Arthur,P.G.: :
Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy. Redox Biol 9:276-286, 2016. Pubmed reference: 27611888 . DOI: 10.1016/j.redox.2016.08.016 . |
| 2015 |
Atencia-Fernandez,S.,Shiel,R.E.,Mooney,C.T.,Nolan,C.M.: :
Muscular dystrophy in the Japanese Spitz: an inversion disrupts the DMD and RPGR genes. Anim Genet 46:175-84, 2015. Pubmed reference: 25644216 . DOI: 10.1111/age.12266 . |
| 2015 |
Duan,D.: :
Duchenne Muscular Dystrophy Gene Therapy in the Canine Model. Hum Gene Ther Clin Dev :, 2015. Pubmed reference: 25710459 . DOI: 10.1089/humc.2015.006 . |
| 2015 |
Duan,D.,Hakim,C.H.,Ambrosio,C.E.,Smith,B.F.,Sweeney,H.L.: :
Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al. Dis Model Mech 8:193-4, 2015. Pubmed reference: 25740329 . DOI: 10.1242/dmm.019216 . |
| 2015 |
Jenkins,C.A.,Forman,O.P.: :
Identification of a novel frameshift mutation in the DMD gene as the cause of muscular dystrophy in a Norfolk terrier dog. Canine Genet Epidemiol 2:7, 2015. Pubmed reference: 26401335 . DOI: 10.1186/s40575-015-0019-4 . |
| 2015 |
Robriquet,F.,Lardenois,A.,Babarit,C.,Larcher,T.,Dubreil,L.,Leroux,I.,Zuber,C.,Ledevin,M.,Deschamps,J.Y.,Fromes,Y.,Cherel,Y.,Guevel,L.,Rouger,K.: :
Differential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell Transplantation. PLoS One 10:e0123336, 2015. Pubmed reference: 25955839 . DOI: 10.1371/journal.pone.0123336 . |
| 2015 |
Vieira,N.M.,Elvers,I.,Alexander,M.S.,Moreira,Y.B.,Eran,A.,Gomes,J.P.,Marshall,J.L.,Karlsson,E.K.,Verjovski-Almeida,S.,Lindblad-Toh,K.,Kunkel,L.M.,Zatz,M.: :
Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype. Cell 163:1204-13, 2015. Pubmed reference: 26582133 . DOI: 10.1016/j.cell.2015.10.049 . |
| 2015 |
Steffen,F.,Bilzer,T.,Brands,J.,Golini,L.,Jagannathan,V.,Wiedmer,M.,Drögemüller,M.,Drögemüller,C.,Leeb,T.: :
A Nonsense Variant in COL6A1 in Landseer Dogs with Muscular Dystrophy. G3 (Bethesda) 5:2611-7, 2015. Pubmed reference: 26438297 . DOI: 10.1534/g3.115.021923 . |
| 2014 |
DeVanna,J.C.,Kornegay,J.N.,Bogan,D.J.,Bogan,J.R.,Dow,J.L.,Hawkins,E.C.: :
Respiratory dysfunction in unsedated dogs with golden retriever muscular dystrophy. Neuromuscul Disord 24:63-73, 2014. Pubmed reference: 24295812 . DOI: 10.1016/j.nmd.2013.10.001 . |
| 2014 |
Martin,P.T.,Golden,B.,Okerblom,J.,Camboni,M.,Chandrasekharan,K.,Xu,R.,Varki,A.,Flanigan,K.M.,Kornegay,J.N.: :
A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle. PLoS One 9:e88226, 2014. Pubmed reference: 24505439 . DOI: 10.1371/journal.pone.0088226 . |
| 2014 |
Mead,A.F.,Petrov,M.,Malik,A.S.,Mitchell,M.A.,Childers,M.K.,Bogan,J.R.,Seidner,G.,Kornegay,J.N.,Stedman,H.H.: :
Diaphragm Remodeling and Compensatory Respiratory Mechanics in a Canine Model of Duchenne Muscular Dystrophy. J Appl Physiol (1985) :, 2014. Pubmed reference: 24408990 . DOI: 10.1152/japplphysiol.00833.2013 . |
| 2014 |
Peres,M.A.,daRocha,A.M.,Vannucchi,C.I.,Mendes,C.M.,Cavalcanti,P.V.,Nichi,M.,Ambrosio,C.E.,Miglino,M.A.,Visintin,J.A.,D'ÁvilaAssumpção,M.E.: :
Semen analysis of Golden Retriever healthy dogs and those affected by muscular dystrophy. Andrologia 46:277-82, 2014. Pubmed reference: 23463904 . DOI: 10.1111/and.12079 . |
| 2014 |
Wang,Z.,Halbert,C.L.,Lee,D.,Butts,T.,Tapscott,S.J.,Storb,R.,Miller,A.D.: :
Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model. Gene Ther :, 2014. Pubmed reference: 24500525 . DOI: 10.1038/gt.2014.4 . |
| 2013 |
Araujo,K.P.,Bonuccelli,G.,Duarte,C.N.,Gaiad,T.P.,Moreira,D.F.,Feder,D.,Belizario,J.E.,Miglino,M.A.,Lisanti,M.P.,Ambrosio,C.E.: :
Bortezomib (PS-341) treatment decreases inflammation and partially rescues the expression of the dystrophin-glycoprotein complex in GRMD dogs. PLoS One 8:e61367, 2013. Pubmed reference: 23579193 . DOI: 10.1371/journal.pone.0061367 . |
| 2013 |
Brinkmeyer-Langford,C.,Kornegay,J.N.: :
Comparative Genomics of X-linked Muscular Dystrophies: The Golden Retriever Model. Curr Genomics 14:330-42, 2013. Pubmed reference: 24403852 . DOI: 10.2174/13892029113149990004 . |
| 2013 |
Broeckx,B.J.,Coopman,F.,Verhoeven,G.E.,VanHaeringen,W.,vandeGoor,L.,Bosmans,T.,Gielen,I.,Saunders,J.H.,Soetaert,S.S.,VanBree,H.,VanNeste,C.,VanNieuwerburgh,F.,VanRyssen,B.,Verelst,E.,VanSteendam,K.,Deforce,D.: :
The prevalence of nine genetic disorders in a dog population from Belgium, the Netherlands and Germany. PLoS One 8:e74811, 2013. Pubmed reference: 24069350 . DOI: 10.1371/journal.pone.0074811 . |
| 2013 |
Cotten,S.W.,Kornegay,J.N.,Bogan,D.J.,Wadosky,K.M.,Patterson,C.,Willis,M.S.: :
Genetic myostatin decrease in the golden retriever muscular dystrophy model does not significantly affect the ubiquitin proteasome system despite enhancing the severity of disease. Am J Transl Res 6:43-53, 2013. Pubmed reference: 24349620 . |
| 2013 |
Fan,Z.,Wang,J.,Ahn,M.,Shiloh-Malawsky,Y.,Chahin,N.,Elmore,S.,Bagnell,C.R.,Wilber,K.,An,H.,Lin,W.,Zhu,H.,Styner,M.,Kornegay,J.N.: :
Characteristics of magnetic resonance imaging biomarkers in a natural history study of golden retriever muscular dystrophy. Neuromuscul Disord :, 2013. Pubmed reference: 24295811 . DOI: 10.1016/j.nmd.2013.10.005 . |
| 2013 |
Kane,A.M.,DeFrancesco,T.C.,Boyle,M.C.,Malarkey,D.E.,Ritchey,J.W.,Atkins,C.E.,Cullen,J.M.,Kornegay,J.N.,Keene,B.W.: :
Cardiac structure and function in female carriers of a canine model of Duchenne muscular dystrophy. Res Vet Sci 94:610-7, 2013. Pubmed reference: 23231955 . DOI: 10.1016/j.rvsc.2012.09.027 . |
| 2013 |
Kerwin,W.S.,Naumova,A.,Storb,R.,Tapscott,S.J.,Wang,Z.: :
Mapping contrast agent uptake and retention in MRI studies of myocardial perfusion: case control study of dogs with Duchenne muscular dystrophy. Int J Cardiovasc Imaging 29:819-26, 2013. Pubmed reference: 23070737 . DOI: 10.1007/s10554-012-0137-y . |
| 2013 |
Nghiem,P.P.,Hoffman,E.P.,Mittal,P.,Brown,K.J.,Schatzberg,S.J.,Ghimbovschi,S.,Wang,Z.,Kornegay,J.N.: :
Sparing of the Dystrophin-Deficient Cranial Sartorius Muscle Is Associated with Classical and Novel Hypertrophy Pathways in GRMD Dogs. Am J Pathol 183:1411-24, 2013. Pubmed reference: 24160322 . DOI: 10.1016/j.ajpath.2013.07.013 . |
| 2013 |
Shin,J.H.,Greer,B.,Hakim,C.H.,Zhou,Z.,Chung,Y.C.,Duan,Y.,He,Z.,Duan,D.: :
Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring. PLoS One 8:e59875, 2013. Pubmed reference: 23544107 . DOI: 10.1371/journal.pone.0059875 . |
| 2013 |
Shin,J.H.,Pan,X.,Hakim,C.H.,Yang,H.T.,Yue,Y.,Zhang,K.,Terjung,R.L.,Duan,D.: :
Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy. Mol Ther 21:750-7, 2013. Pubmed reference: 23319056 . DOI: 10.1038/mt.2012.283 . |
| 2013 |
Wang,J.,Fan,Z.,Vandenborne,K.,Walter,G.,Shiloh-Malawsky,Y.,An,H.,Kornegay,J.N.,Styner,M.A.: :
A computerized MRI biomarker quantification scheme for a canine model of Duchenne muscular dystrophy. Int J Comput Assist Radiol Surg 8:763-74, 2013. Pubmed reference: 23299128 . DOI: 10.1007/s11548-012-0810-6 . |
| 2013 |
Wuebbles,R.D.,Sarathy,A.,Kornegay,J.N.,Burkin,D.J.: :
Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy. Dis Model Mech 6:1175-84, 2013. Pubmed reference: 23846963 . DOI: 10.1242/dmm.012211 . |
| 2013 |
Baroncelli,A.B.,Abellonio,F.,Pagano,T.B.,Esposito,I.,Peirone,B.,Papparella,S.,Paciello,O.: :
Muscular Dystrophy in a Dog Resembling Human Becker Muscular Dystrophy. J Comp Pathol :, 2013. Pubmed reference: 24529507 . DOI: 10.1016/j.jcpa.2013.12.006 . |
| 2013 |
Marioni-Henry,K.,Haworth,P.,Scott,H.,Witte,P.,Guo,L.T.,Shelton,G.D.: :
Sarcolemmal specific collagen VI deficient myopathy in a Labrador Retriever. J Vet Intern Med 28:243-9, 2013. Pubmed reference: 24147807 . DOI: 10.1111/jvim.12224 . |
| 2012 |
Barbash,I.M.,Cecchini,S.,Faranesh,A.Z.,Virag,T.,Li,L.,Yang,Y.,Hoyt,R.F.,Kornegay,J.N.,Bogan,J.R.,Garcia,L.,Lederman,R.J.,Kotin,R.M.: :
MRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Gene Ther :, 2012. Pubmed reference: 22551778 . DOI: 10.1038/gt.2012.38 . |
| 2012 |
Barthélémy,I.,Uriarte,A.,Drougard,C.,Unterfinger,Y.,Thibaud,J.L.,Blot,S.: :
Effects of an immunosuppressive treatment in the GRMD dog model of Duchenne muscular dystrophy. PLoS One 7:e48478, 2012. Pubmed reference: 23185260 . DOI: 10.1371/journal.pone.0048478 . |
| 2012 |
Bedu,A.S.,Labruyère,J.J.,LaurentThibaud,J.,Barthélémy,I.,Leperlier,D.,Saunders,J.H.,Blot,S.: :
Age-related thoracic radiographic changes in Golden and Labrador Retriever muscular dystrophy Vet Radiol Ultrasound :, 2012. Pubmed reference: 22702494 . DOI: 10.1111/j.1740-8261.2012.01948.x . |
| 2012 |
Cassano,M.,Berardi,E.,Crippa,S.,Toelen,J.,Barthelemy,I.,Micheletti,R.,Chuah,M.,Vanderdriessche,T.,Debyser,Z.,Blot,S.,Sampaolesi,M.: :
Alteration of cardiac progenitor cell potency in GRMD dogs. Cell Transplant :, 2012. Pubmed reference: 22513051 . DOI: 10.3727/096368912X638919 . |
| 2012 |
Kornegay,J.N.,Bogan,J.R.,Bogan,D.J.,Childers,M.K.,Li,J.,Nghiem,P.,Detwiler,D.A.,Larsen,C.A.,Grange,R.W.,Bhavaraju-Sanka,R.K.,Tou,S.,Keene,B.P.,Howard,J.F.,Wang,J.,Fan,Z.,Schatzberg,S.J.,Styner,M.A.,Flanigan,K.M.,Xiao,X.,Hoffman,E.P.: :
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mamm Genome 23:85-108, 2012. Pubmed reference: 22218699 . DOI: 10.1007/s00335-011-9382-y . |
| 2012 |
Su,J.B.,Cazorla,O.,Blot,S.,Blanchard-Gutton,N.,AitMou,Y.,Barthélémy,I.,Sambin,L.,Sampedrano,C.C.,Gouni,V.,Unterfinger,Y.,Aguilar,P.,Thibaud,J.L.,Bizé,A.,Pouchelon,J.L.,Dabiré,H.,Ghaleh,B.,Berdeaux,A.,Chetboul,V.,Lacampagne,A.,Hittinger,L.: :
Bradykinin restores left ventricular function, sarcomeric protein phosphorylation, and e/nNOS levels in dogs with Duchenne muscular dystrophy cardiomyopathy. Cardiovasc Res 95:86-96, 2012. Pubmed reference: 22562664 . DOI: 10.1093/cvr/cvs161 . |
| 2012 |
Vieira,N.M.,Valadares,M.,Zucconi,E.,Secco,M.,Bueno,C.R.,Brandalise,V.,Assoni,A.,Gomes,J.,Landini,V.,Andrade,T.,Caetano,H.V.,Vainzof,M.,Zatz,M.: :
Human adipose-derived mesenchymal stromal cells injected systemically into GRMD dogs without immunosuppression are able to reach the host muscle and express human dystrophin. Cell Transplant 21:1407-17, 2012. Pubmed reference: 23168016 . DOI: 10.3727/096368911X . |
| 2012 |
Vulin,A.,Barthélémy,I.,Goyenvalle,A.,Thibaud,J.L.,Beley,C.,Griffith,G.,Benchaouir,R.,leHir,M.,Unterfinger,Y.,Lorain,S.,Dreyfus,P.,Voit,T.,Carlier,P.,Blot,S.,Garcia,L.: :
Muscle function recovery in golden retriever muscular dystrophy after AAV1-U7 exon skipping. Mol Ther 20:2120-33, 2012. Pubmed reference: 22968479 . DOI: 10.1038/mt.2012.181 . |
| 2012 |
Wang,Z.,Storb,R.,Halbert,C.L.,Banks,G.B.,Butts,T.M.,Finn,E.E.,Allen,J.M.,Miller,A.D.,Chamberlain,J.S.,Tapscott,S.J.: :
Successful regional delivery and long-term expression of a dystrophin gene in canine muscular dystrophy: a preclinical model for human therapies. Mol Ther 20:1501-7, 2012. Pubmed reference: 22692496 . DOI: 10.1038/mt.2012.111 . |
| 2012 |
Yang,H.T.,Shin,J.H.,Hakim,C.H.,Pan,X.,Terjung,R.L.,Duan,D.: :
Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy. PLoS One 7:e44438, 2012. Pubmed reference: 22973449 . DOI: 10.1371/journal.pone.0044438 . |
| 2012 |
Yokota,T.,Nakamura,A.,Nagata,T.,Saito,T.,Kobayashi,M.,Aoki,Y.,Echigoya,Y.,Partridge,T.,Hoffman,E.P.,Takeda,S.: :
Extensive and prolonged restoration of dystrophin expression with vivo-morpholino-mediated multiple exon skipping in dystrophic dogs. Nucleic Acid Ther 22:306-15, 2012. Pubmed reference: 22888777 . DOI: 10.1089/nat.2012.0368 . |
| 2011 |
Kornegay,JN.,Bogan,JR.,Bogan,DJ.,Childers,MK.,Grange,RW.: :
Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements. Methods Mol Biol 709:105-23, 2011. Pubmed reference: 21194024 . DOI: 10.1007/978-1-61737-982-6_7 . |
| 2011 |
Guevel,L.,Lavoie,J.R.,Perez-Iratxeta,C.,Rouger,K.,Dubreil,L.,Feron,M.,Talon,S.,Brand,M.,Megeney,L.A.: :
Quantitative proteomic analysis of dystrophic dog muscle. J Proteome Res 10:2465-78, 2011. Pubmed reference: 21410286 . DOI: 10.1021/pr2001385 . |
| 2011 |
Hoffman,E.P.,Bronson,A.,Levin,A.A.,Takeda,S.,Yokota,T.,Baudy,A.R.,Connor,E.M.: :
Restoring dystrophin expression in duchenne muscular dystrophy muscle progress in exon skipping and stop codon read through. Am J Pathol 179:12-22, 2011. Pubmed reference: 21703390 . DOI: 10.1016/j.ajpath.2011.03.050 . |
| 2011 |
Kornegay,JN.,Bogan,JR.,Bogan,DJ.,Childers,MK.,Grange,RW.: :
Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements. Methods Mol Biol 709:105-23, 2011. Pubmed reference: 21194024 . DOI: 10.1007/978-1-61737-982-6_7 . |
| 2011 |
Nakamura,A.,Takeda,S.: :
Mammalian models of Duchenne Muscular Dystrophy: pathological characteristics and therapeutic applications. J Biomed Biotechnol 2011:184393, 2011. Pubmed reference: 21274260 . DOI: 10.1155/2011/184393 . |
| 2011 |
Olby,NJ.,Sharp,NJ.,Nghiem,PE.,Keene,BW.,DeFrancesco,TC.,Sidley,JA.,Kornegay,JN.,Schatzberg,SJ.: :
Clinical progression of X-linked muscular dystrophy in two German Shorthaired Pointers. J Am Vet Med Assoc 238:207-12, 2011. Pubmed reference: 21235374 . DOI: 10.2460/javma.238.2.207 . |
| 2011 |
Smith,BF.,Yue,Y.,Woods,PR.,Kornegay,JN.,Shin,JH.,Williams,RR.,Duan,D.: :
An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed. Lab Invest 91:216-31, 2011. Pubmed reference: 20714321 . DOI: 10.1038/labinvest.2010.146 . |
| 2011 |
Yokota,T.,Hoffman,E.,Takeda,S.: :
Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy. Methods Mol Biol 709:299-312, 2011. Pubmed reference: 21194037 . DOI: 10.1007/978-1-61737-982-6_20 . |
| 2010 |
Kornegay,JN.,Li,J.,Bogan,JR.,Bogan,DJ.,Chen,C.,Zheng,H.,Wang,B.,Qiao,C.,Howard,JF.,Xiao,X.: :
Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs. Mol Ther 18:1501-8, 2010. Pubmed reference: 20517298 . DOI: 10.1038/mt.2010.94 . |
| 2010 |
Partridge,T.: :
The potential of exon skipping for treatment for Duchenne muscular dystrophy. J Child Neurol 25:1165-70, 2010. Pubmed reference: 20519674 . DOI: 10.1177/0883073810371130 . |
| 2010 |
Saito,T.,Nakamura,A.,Aoki,Y.,Yokota,T.,Okada,T.,Osawa,M.,Takeda,S.: :
Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient. PLoS One 5:e12239, 2010. Pubmed reference: 20805873 . DOI: 10.1371/journal.pone.0012239 . |
| 2010 |
Walmsley,GL.,Arechavala-Gomeza,V.,Fernandez-Fuente,M.,Burke,MM.,Nagel,N.,Holder,A.,Stanley,R.,Chandler,K.,Marks,SL.,Muntoni,F.,Shelton,GD.,Piercy,RJ.: :
A duchenne muscular dystrophy gene hot spot mutation in dystrophin-deficient cavalier king charles spaniels is amenable to exon 51 skipping. PLoS One 5:e8647, 2010. Pubmed reference: 20072625 . DOI: 10.1371/journal.pone.0008647 . |
| 2010 |
Zucconi,E.,Valadares,MC.,Vieira,NM.,Bueno,CR.,Secco,M.,Jazedje,T.,daSilva,HC.,Vainzof,M.,Zatz,M.: :
Ringo: discordance between the molecular and clinical manifestation in a golden retriever muscular dystrophy dog. Neuromuscul Disord 20:64-70, 2010. Pubmed reference: 19944604 . DOI: 10.1016/j.nmd.2009.10.011 . |
| 2009 |
Piercy,RJ.,Walmsley,G.: :
Muscular dystrophy in Cavalier King Charles spaniels. Vet Rec 165:62, 2009. Pubmed reference: 19596683 . |
| 2009 |
Willmann,R.,Possekel,S.,Dubach-Powell,J.,Meier,T.,Ruegg,MA.: :
Mammalian animal models for Duchenne muscular dystrophy. Neuromuscul Disord 19:241-9, 2009. Pubmed reference: 19217290 . DOI: 10.1016/j.nmd.2008.11.015 . |
| 2009 |
Yokota,T.,Lu,QL.,Partridge,T.,Kobayashi,M.,Nakamura,A.,Takeda,S.,Hoffman,E.: :
Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs. Ann Neurol 65:667-76, 2009. Pubmed reference: 19288467 . DOI: 10.1002/ana.21627 . |
| 2009 |
Zucconi,E.,Jazedje,T.,Valadares,M.C.,Zatz,M.: :
Comments to the paper by Ambrósio CE, Fadel L, Gaiad TP, Martins DS, et al. [Identification of three distinguishable phenotypes in golden retriever muscular dystrophy (Genet. Mol. Res. 2009 Apr 7;8 (2): 389-396)]. Genet Mol Res 8:818-21, 2009. Pubmed reference: 19731203 . DOI: 10.4238/vol8-3gmrCarta01 . |
| 2008 |
Banks,G.B.,Chamberlain,J.S.: :
The value of mammalian models for duchenne muscular dystrophy in developing therapeutic strategies. Curr Top Dev Biol 84:431-53, 2008. Pubmed reference: 19186250 . DOI: 10.1016/S0070-2153(08)00609-1 . |
| 2008 |
Urasawa,N.,Wada,MR.,Machida,N.,Yuasa,K.,Shimatsu,Y.,Wakao,Y.,Yuasa,S.,Sano,T.,Nonaka,I.,Nakamura,A.,Takeda,S.: :
Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. Circulation 117:2437-48, 2008. Pubmed reference: 18458171 . DOI: 10.1161/CIRCULATIONAHA.107.739326 . |
| 2008 |
Deitz,K.,Morrison,J.A.,Kline,K.,Guo,L.T.,Shelton,G.D.: :
Sarcoglycan-deficient muscular dystrophy in a Boston Terrier. J Vet Intern Med 22:476-80, 2008. Pubmed reference: 18371037 . DOI: 10.1111/j.1939-1676.2008.0080.x . |
| 2007 |
Smith,B.F.,Kornegay,J.N.,Duan,D.: :
Independent canine models of Duchenne muscular dystrophy due to intronic insertions of repetitive DNA. Mol Ther. 15(Suppl. 1):S51, 2007. |
| 2006 |
McClorey,G.,Moulton,HM.,Iversen,PL.,Fletcher,S.,Wilton,SD.: :
Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD. Gene Ther 13:1373-81, 2006. Pubmed reference: 16724091 . DOI: 10.1038/sj.gt.3302800 . |
| 2005 |
Shelton,GD.,Engvall,E.: :
Canine and feline models of human inherited muscle diseases. Neuromuscul Disord 15:127-38, 2005. Pubmed reference: 15694134 . DOI: 10.1016/j.nmd.2004.10.019 . |
| 2005 |
Chetboul,V.,Tessier-Vetzel,D.,Escriou,C.,Tissier,R.,Carlos,C.,Boussouf,M.,Pouchelon,JL.,Blot,S.,Derumeaux,G.: :
Diagnostic potential of natriuretic peptides in the occult phase of golden retriever muscular dystrophy cardiomyopathy. J Vet Intern Med 18:845-50, 2005. Pubmed reference: 15638261 . |
| 2005 |
Nguyen,F.,Guigand,L.,Goubault-Leroux,I.,Wyers,M.,Cherel,Y.: :
Microvessel density in muscles of dogs with golden retriever muscular dystrophy. Neuromuscul Disord 15:154-63, 2005. Pubmed reference: 15694137 . DOI: 10.1016/j.nmd.2004.11.002 . |
| 2005 |
Shelton,GD.,Engvall,E.: :
Canine and feline models of human inherited muscle diseases. Neuromuscul Disord 15:127-38, 2005. Pubmed reference: 15694134 . DOI: 10.1016/j.nmd.2004.10.019 . |
| 2005 |
Shimatsu,Y.,Yoshimura,M.,Yuasa,K.,Urasawa,N.,Tomohiro,M.,Nakura,M.,Tanigawa,M.,Nakamura,A.,Takeda,S.: :
Major clinical and histopathological characteristics of canine X-linked muscular dystrophy in Japan, CXMDJ. Acta Myol 24:145-54, 2005. Pubmed reference: 16550932 . |
| 2004 |
Chetboul,V.,Carlos,C.,Blot,S.,Thibaud,JL.,Escriou,C.,Tissier,R.,Retortillo,JL.,Pouchelon,JL.: :
Tissue Doppler assessment of diastolic and systolic alterations of radial and longitudinal left ventricular motions in Golden Retrievers during the preclinical phase of cardiomyopathy associated with muscular dystrophy. Am J Vet Res 65:1335-41, 2004. Pubmed reference: 15524319 . |
| 2004 |
Chetboul,V.,Escriou,C.,Tessier,D.,Richard,V.,Pouchelon,JL.,Thibault,H.,Lallemand,F.,Thuillez,C.,Blot,S.,Derumeaux,G.: :
Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathy. Eur Heart J 25:1934-9, 2004. Pubmed reference: 15522464 . DOI: 10.1016/j.ehj.2004.08.013 . |
| 2004 |
Dell'Agnola,C.,Wang,Z.,Storb,R.,Tapscott,SJ.,Kuhr,CS.,Hauschka,SD.,Lee,RS.,Sale,GE.,Zellmer,E.,Gisburne,S.,Bogan,J.,Kornegay,JN.,Cooper,BJ.,Gooley,TA.,Little,MT.: :
Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs. Blood 104:4311-8, 2004. Pubmed reference: 15328150 . DOI: 10.1182/blood-2004-06-2247 . |
| 2004 |
Jones,B.R.,Brennan,S.,Mooney,C.T.,Callanan,J.J.,McAllister,H.,Guo,L.T.,Martin,P.T.,Engvall,E.,Shelton,G.D.: :
Muscular dystrophy with truncated dystrophin in a family of Japanese Spitz dogs. J Neurol Sci 217:143-9, 2004. Pubmed reference: 14706216 . |
| 2004 |
Liu,JM.,Okamura,CS.,Bogan,DJ.,Bogan,JR.,Childers,MK.,Kornegay,JN.: :
Effects of prednisone in canine muscular dystrophy. Muscle Nerve 30:767-73, 2004. Pubmed reference: 15468337 . DOI: 10.1002/mus.20154 . |
| 2004 |
Shelton,G.D.: :
Muscular dystrophies: expanding our knowledge in companion animals. Vet J 168:6-8, 2004. Pubmed reference: 15158202 . DOI: 10.1016/j.tvjl.2004.03.013 . |
| 2004 |
Schatzberg,SJ.,Shelton,GD.: :
Newly identified neuromuscular disorders. Vet Clin North Am Small Anim Pract 34:1497-524, 2004. Pubmed reference: 15474686 . DOI: 10.1016/j.cvsm.2004.06.001 . |
| 2003 |
Cerletti,M.,Negri,T.,Cozzi,F.,Colpo,R.,Andreetta,F.,Croci,D.,Davies,K.E.,Cornelio,F.,Pozza,O.,Karpati,G.,Gilbert,R.,Mora,M.: :
Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer Gene Therapy 10:750-7, 2003. Pubmed reference: 12704413 . DOI: 10.1038/sj.gt.3301941 . |
| 2003 |
Collins,C.A.,Morgan,J.E.: :
Duchenne's muscular dystrophy: animal models used to investigate pathogenesis and develop therapeutic strategies. Int J Exp Pathol 84:165-72, 2003. Pubmed reference: 14632630 . |
| 2003 |
Kornegay,J.N.,Cundiff,D.D.,Bogan,D.J.,Bogan,J.R.,Okamura,C.S.: :
The cranial sartorius muscle undergoes true hypertrophy in dogs with golden retriever muscular dystrophy Neuromuscular Disorders 13:493-500, 2003. Pubmed reference: 12899877 . |
| 2003 |
Shimatsu,Y.,Katagiri,K.,Furuta,T.,Nakura,M.,Tanioka,Y.,Yuasa,K.,Tomohiro,M.,Kornegay,J.N.,Nonaka,I.,Takeda,S.: :
Canine X-linked muscular dystrophy in Japan (CXMDJ) Experimental Animals 52:93-7, 2003. Pubmed reference: 12806883 . |
| 2002 |
Shelton,G.D.,Engvall,E.: :
Muscular dystrophies and other inherited myopathies Veterinary Clinics of North America - Small Animal Practice 32:103-+, 2002. |
| 2002 |
Bergman,R.L.,Inzana,K.D.,Monroe,W.E.,Shell,L.G.,Liu,L.A.,Engvall,E.,Shelton,G.D.: :
Dystrophin-deficient muscular dystrophy in a labrador retriever Journal of the American Animal Hospital Association 38:255-261, 2002. Pubmed reference: 12022412 . |
| 2002 |
Childers,M.K.,Okamura,C.S.,Bogan,D.J.,Bogan,J.R.,Petroski,G.F.,McDonald,K.,Kornegay,J.N.: :
Eccentric contraction injury in dystrophic canine muscle Archives of Physical Medicine & Rehabilitation 83:1572-1578, 2002. |
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[Animal models of Duchenne muscular dystrophy]. Rev Prat 52:937-40, 2002. Pubmed reference: 12063758 . |
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Nguyen,F.,Cherel,Y.,Guigand,L.,Goubault-Leroux,I.,Wyers,M.: :
Muscle lesions associated with dystrophin deficiency in neonatal golden retriever puppies Journal of Comparative Pathology 126:100-108, 2002. Pubmed reference: 11944998 . DOI: 10.1053/jcpa.2001.0526 . |
| 2002 |
Passerini,L.,Bernasconi,P.,Baggi,F.,Confalonieri,P.,Cozzi,F.,Cornelio,F.,Mantegazza,R.: :
Fibrogenic cytokines and extent of fibrosis in muscle of dogs with X-linked golden retriever muscular dystrophy Neuromuscular Disorders 12:828-835, 2002. Pubmed reference: 12398833 . |
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Shelton,G.D.,Engvall,E.: :
Muscular dystrophies and other inherited myopathies. Vet Clin North Am Small Anim Pract 32:103-24, 2002. Pubmed reference: 11785725 . |
| 2001 |
Childers,M.K.,Okamura,C.S.,Bogan,D.J.,Bogan,J.R.,Sullivan,M.J.,Kornegay,J.N.: :
Myofiber injury and regeneration in a canine homologue of Duchenne muscular dystrophy American Journal of Physical Medicine & Rehabilitation 80:175-181, 2001. Pubmed reference: 11237271 . |
| 2001 |
Cozzi,F.,Cerletti,M.,Luvoni,G.C.,Lombardo,R.,Brambilla,P.G.,Faverzani,S.,Blasevich,F.,Cornelio,F.,Pozza,O.,Mora,M.: :
Development of muscle pathology in canine X-linked muscular dystrophy. II. Quantitative characterization of histopathological progression during postnatal skeletal muscle development Acta Neuropathologica 101:469-478, 2001. Pubmed reference: 11484818 . |
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Fletcher,S.,Carville,K.S.,Howell,J.M.,Mann,C.J.,Wilton,S.D.: :
Evaluation of a short interspersed nucleotide element in the 3 ' untranslated region of the defective dystrophin gene of dogs with muscular dystrophy American Journal of Veterinary Research 62:1964-1968, 2001. Pubmed reference: 11763189 . |
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Fletcher,S.,Ly,T.,Duff,R.M.,Howell,J.M.,Wilton,S.D.: :
Cryptic splicing involving the splice site mutation in the canine model of Duchenne muscular dystrophy Neuromuscular Disorders 11:239-243, 2001. Pubmed reference: 11297938 . |
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Klopp,L.S.,Smith,B.F.: :
Autosomal recessive muscular dystrophy in Labrador retrievers Compendium on Continuing Education for the Practicing Veterinarian 22:121-+, 2000. |
| 2000 |
Bartlett,R.J.,Stockinger,S.,Denis,M.M.,Bartlett,W.T.,Inverardi,L.,Le,T.T.,Man,N.T.,Morris,G.E.,Bogan,D.J.,Metcalf-Bogan,J.,Kornegay,J.N.: :
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide Nature Biotechnology 18:615-622, 2000. Pubmed reference: 10835598 . DOI: 10.1038/76448 . |
| 2000 |
Bartlett,R.J.,Stockinger,S.,Denis,M.M.,Bartlett,W.T.,Inverardi,L.,Le,T.T.,Man,T.M.,Morris,G.E.,Bogan,D.J.,Metcalf-Bogan,J.,Kornegay,J.N.: :
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide (vol 18, pg 615, 2000) Nature Biotechnology 18:1209, 2000. DOI: 10.1038/81216 . |
| 2000 |
Wetterman,C.A.,Harkin,K.R.,Cash,W.C.,Nietfield,J.C.,Shelton,G.D.: :
Hypertrophic muscular dystrophy in a young dog Journal of the American Veterinary Medical Association 216:878-+, 2000. |
| 1999 |
Honeyman,K.,Carville,K.S.,Howell,J.M.,Fletcher,S.,Wilton,S.D.: :
Development of a snapback method of single-strand conformation polymorphism analysis for genotyping Golden Retrievers for the X-linked muscular dystrophy allele American Journal of Veterinary Research 60:734-737, 1999. Pubmed reference: 10376903 . |
| 1999 |
Kornegay,J.N.,Bogan,D.J.,Bogan,J.R.,Childers,M.K.,Cundiff,D.D.,Petroski,G.F.,Schueler,R.O.: :
Contraction force generated by tarsal joint flexion and extension in dogs with golden retriever muscular dystrophy Journal of the Neurological Sciences 166:115-121, 1999. Pubmed reference: 10475104 . |
| 1999 |
Lanfossi,M.,Cozzi,F.,Bugini,D.,Colombo,S.,Scarpa,P.,Morandi,L.,Galbiati,S.,Cornelio,F.,Pozza,O.,Mora,M.: :
Development of muscle pathology in canine X-linked muscular dystrophy. I. Delayed postnatal maturation of affected and normal muscle as revealed by myosin isoform analysis and utrophin expression Acta Neuropathologica 97:127-138, 1999. Pubmed reference: 9928823 . |
| 1999 |
Schatzberg,S.J.,Olby,N.J.,Breen,M.,Anderson,L.V.B.,Langford,C.F.,Dickens,H.F.,Wilton,S.D.,Zeiss,C.J.,Binns,M.M.,Kornegay,J.N.,Morris,G.E.,Sharp,N.J.H.: :
Molecular analysis of a spontaneous dystrophin 'knockout' dog Neuromuscular Disorders 9:289-295, 1999. Pubmed reference: 10407848 . |
| 1999 |
Schatzberg,S.,Olby,N.,Steingold,S.,Keene,B.,Atkins,C.,Meurs,K.,Solomon,G.,Goedegebuure,S.A.,Wilton,S.,Sharp,N.: :
A polymerase chain reaction screening strategy for the promoter of the canine dystrophin gene American Journal of Veterinary Research 60:1040-1046, 1999. Pubmed reference: 10490068 . |
| 1998 |
Hanson,S.M.,Smith,M.O.,Walker,T.L.,Shelton,G.D.: :
Juvenile-onset distal myopathy in rottweiler dogs Journal of Veterinary Internal Medicine 12:103-108, 1998. Pubmed reference: 9560767 . |
| 1998 |
Howell,J.M.,Lochmüller,H.,O'Hara,A.,Fletcher,S.,Kakulas,B.A.,Massie,B.,Nalbantoglu,J.,Karpati,G.: :
High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression. Hum Gene Ther 9:629-34, 1998. Pubmed reference: 9551611 . DOI: 10.1089/hum.1998.9.5-629 . |
| 1998 |
Nonaka,I.: :
Animal models of muscular dystrophies. Lab Anim Sci 48:8-17, 1998. Pubmed reference: 9517883 . |
| 1997 |
Howell,J.M.,Fletcher,S.,Kakulas,B.A.,Ohara,M.,Lochmuller,H.,Karpati,G.: :
Use of the dog model for duchenne muscular dystrophy in gene therapy trials Neuromuscular Disorders 7:325-328, 1997. Pubmed reference: 9267846 . |
| 1997 |
Howell,J.M.,Fletcher,S.,Kakulas,B.A.,Ohara,M.,Lochmuller,H.,Karpati,G.: :
Use of the dog model for duchenne muscular dystrophy in gene therapy trials Neuromuscular Disorders 7:325-328, 1997. Pubmed reference: 9267846 . |
| 1996 |
Bartlett,R.J.,Winand,N.J.,Secore,S.L.,Singer,J.T.,Fletcher,S.,Wilton,S.,Bogan,D.J.,Metcalfbogan,J.R.,Bartlett,W.T.,Howell,J.M.,Cooper,B.J.,Kornegay,J.N.: :
Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs American Journal of Veterinary Research 57:650-654, 1996. Pubmed reference: 8723876 . |
| 1996 |
Bartlett,R.J.,Winand,N.J.,Secore,S.L.,Singer,J.T.,Fletcher,S.,Wilton,S.,Bogan,D.J.,Metcalfbogan,J.R.,Bartlett,W.T.,Howell,J.M.,Cooper,B.J.,Kornegay,J.N.: :
Mutation segregation and rapid carrier detection of X-linked muscular dystrophy in dogs American Journal of Veterinary Research 57:650-654, 1996. Pubmed reference: 8723876 . |
| 1995 |
Koh,G.Y.,Soonpaa,M.H.,Klug,M.G.,Pride,H.P.,Cooper,B.J.,Zipes,D.P.,Field,L.J.: :
Stable fetal cardiomyocyte grafts in the hearts of dystrophic mice and dogs Journal of Clinical Investigation 96:2034-2042, 1995. Pubmed reference: 7560097 . DOI: 10.1172/JCI118251 . |
| 1995 |
Vanham,L.M.L.,Desmidt,M.,Tshamala,M.,Hoorens,J.K.,Mattheeuws,D.R.G.: :
Canine X-linked muscular dystrophy in Belgian Groenendaeler shepherds Vlaams Diergeneeskundig Tijdschrift 64:102-106, 1995. |
| 1995 |
Vanham,L.M.L.,Roels,S.L.M.F.,Hoorens,J.K.: :
Congenital dystrophy-like myopathy in a brittany spaniel puppy Progress in Veterinary Neurology 6:135-138, 1995. |
| 1994 |
Gorospe,J.R.M.,Tharp,M.D.,Hinckley,J.,Kornegay,J.N.,Hoffman,E.P.: :
A Role for Mast Cells in the Progression of Duchenne Muscular Dystrophy - Correlations in Dystrophin-Deficient Humans, Dogs, and Mice Journal of the Neurological Sciences 122:44-56, 1994. Pubmed reference: 8195802 . |
| 1994 |
Kornegay,J.N.,Sharp,N.J.H.,Schueler,R.O.,Betts,C.W.: :
Tarsal joint contracture in dogs with golden retriever muscular dystrophy Laboratory Animal Science 44:331-333, 1994. Pubmed reference: 7983843 . |
| 1994 |
Pacioretty,L.M.,Cooper,B.J.,Gilmour,R.F.: :
Reduction of the transient outward potassium current in canine X-linked muscular dystrophy Circulation 90:1350-1356, 1994. Pubmed reference: 8087945 . |
| 1994 |
Prattis,S.M.,Horton,S.B.,Vancamp,S.D.,Kornegay,J.N.: :
Immunohistochemical Detection of Neural Cell Adhesion Molecule and Laminin in X-Linked Dystrophic Dogs and Mdx Mice Journal of Comparative Pathology 110:253-266, 1994. Pubmed reference: 8040390 . |
| 1994 |
Wilson,L.A.,Cooper,B.J.,Dux,L.,Dubowitz,V.,Sewry,C.A.: :
Expression of utrophin (dystrophin-related protein) during regeneration and maturation of skeletal muscle in canine X- linked muscular dystrophy Neuropathology and Applied Neurobiology 20:359-367, 1994. Pubmed reference: 7808586 . |
| 1994 |
Wilson,L.A.,Dux,L.,Cooper,B.J.,Dubowitz,V.,Sewry,C.A.: :
Experimental Regeneration in Canine Muscular Dystrophy .2. Expression of Myosin Heavy Chain Isoforms Neuromuscular Disorders 4:25-37, 1994. Pubmed reference: 7513568 . |
| 1994 |
Winand,N.,Pradham,D.,Cooper,B.: :
Molecular characterization of severe Duchenne-type muscular dystrophy in a family of Rottweiler dogs. Molecular Mechanism of Neuromuscular Disease. Muscular Dystrophy Association; Tucson, Ariz, USA :, 1994. |
| 1993 |
Anderson,J.E.,Kakulas,B.A.,Jacobsen,P.F.,Johnsen,R.D.,Kornegay,J.N.,Grounds,M.D.: :
Comparison of Basic Fibroblast Growth Factor in X-Linked Dystrophin-Deficient Myopathies of Human, Dog and Mouse Growth Factors 9:107-121, 1993. Pubmed reference: 8217214 . |
| 1993 |
Prattis,S.M.,Gebhart,D.H.,Dickson,G.,Watt,D.J.,Kornegay,J.N.: :
Magnetic Affinity Cell Sorting (MACS) Separation and Flow Cytometric Characterization of Neural Cell Adhesion Molecule- Positive, Cultured Myogenic Cells from Normal and Dystrophic Dogs Experimental Cell Research 208:453-464, 1993. Pubmed reference: 8375474 . DOI: 10.1006/excr.1993.1267 . |
| 1993 |
Vanham,L.M.L.,Desmidt,M.,Tshamala,M.,Hoorens,J.K.,Mattheeuws,D.R.G.: :
Canine X-Linked Muscular Dystrophy in Belgian Groenendaeler Shepherds Journal of the American Animal Hospital Association 29:570-574, 1993. |
| 1992 |
Sharp,N.J.H.,Kornegay,J.N.,Vancamp,S.D.,Herbstreith,M.H.,Secore,S.L.,Kettle,S.,Hung,W.Y.,Constantinou,C.D.,Dykstra,M.J.,Roses,A.D.,Bartlett,R.J.: :
An Error in Dystrophin Messenger RNA Processing in Golden Retriever Muscular Dystrophy, an Animal Homologue of Duchenne Muscular Dystrophy Genomics 13:115-121, 1992. Pubmed reference: 1577476 . |
| 1992 |
Valentine,B.A.,Winand,N.J.,Pradhan,D.,Moise,N.S.,Delahunta,A.,Kornegay,J.N.,Cooper,B.J.: :
Canine X-Linked Muscular Dystrophy as an Animal Model of Duchenne Muscular Dystrophy - A Review American Journal of Medical Genetics 42:352-356, 1992. Pubmed reference: 1536178 . DOI: 10.1002/ajmg.1320420320 . |
| 1992 |
Cooper,B.J.,Kakulas,B.A.,Howell,J.M.,Roses,A.D.: :
The xmd Dog - Molecular and Phenotypic Characteristics Duchenne Muscular Dystrophy :109-111, 1992. |
| 1992 |
Kakulas,B.A.,Bartlett,R.J.,Howell,J.M.,Roses,A.D.: :
Potential Strategies for Gene Therapy in Golden Retriever Muscular Dystrophy Duchenne Muscular Dystrophy :265-277, 1992. |
| 1992 |
Sharp,N.J.H.,Kakulas,B.A.,Kornegay,J.N.,Howell,J.M.,Vancamp,S.D.,Herbstreith,M.H.,Secore,S.L.,Kettle,S.,Dykstra,M.J.,Constantinou,C.D.,Roses,A.D.,Bartlett,R.J.: :
Exon Skipping During Dystrophin Messenger RNA Processing in the Canine Homologue of Duchenne Muscular Dystrophy Duchenne Muscular Dystrophy :113-126, 1992. |
| 1992 |
Sharp,N.J.H.,Kornegay,J.N.,Vancamp,S.D.,Herbstreith,M.H.,Secore,S.L.,Kettle,S.,Hung,W.Y.,Constantinou,C.D.,Dykstra,M.J.,Roses,A.D.,Bartlett,R.J.: :
An Error in Dystrophin Messenger RNA Processing in Golden Retriever Muscular Dystrophy, an Animal Homologue of Duchenne Muscular Dystrophy Genomics 13:115-121, 1992. Pubmed reference: 1577476 . |
| 1992 |
Valentine,B.A.,Winand,N.J.,Pradhan,D.,Moise,N.S.,Delahunta,A.,Kornegay,J.N.,Cooper,B.J.: :
Canine X-Linked Muscular Dystrophy as an Animal Model of Duchenne Muscular Dystrophy - A Review American Journal of Medical Genetics 42:352-356, 1992. Pubmed reference: 1536178 . DOI: 10.1002/ajmg.1320420320 . |
| 1991 |
Mccully,K.,Giger,U.,Argov,Z.,Valentine,B.,Cooper,B.,Chance,B.,Bank,W.: :
Canine X-Linked Muscular Dystrophy Studied with Invivo Phosphorus Magnetic Resonance Spectroscopy Muscle & Nerve 14:1091-1098, 1991. Pubmed reference: 1745283 . DOI: 10.1002/mus.880141109 . |
| 1991 |
Mehta,J.R.,Braund,K.G.,Hegreberg,G.A.,Thukrall,V.: :
Lipid Fluidity and Composition of the Erythrocyte Membrane from Healthy Dogs and Labrador Retrievers with Hereditary Muscular Dystrophy Neurochemical Research 16:129-135, 1991. Pubmed reference: 1908955 . |
| 1991 |
Valentine,B.A.,Chandler,S.K.,Cummings,J.F.,Cooper,B.J.: :
Invitro Characteristics of Normal and Dystrophic Skeletal Muscle from Dogs American Journal of Veterinary Research 52:104-107, 1991. Pubmed reference: 2021236 . |
| 1991 |
Moise,NS.,Valentine,BA.,Brown,CA.,Erb,HN.,Beck,KA.,Cooper,BJ.,Gilmour,RF.: :
Duchenne's cardiomyopathy in a canine model: electrocardiographic and echocardiographic studies. J Am Coll Cardiol 17:812-20, 1991. Pubmed reference: 1825214 . |
| 1991 |
Partridge,T.: :
Animal models of muscular dystrophy--what can they teach us? Neuropathol Appl Neurobiol 17:353-63, 1991. Pubmed reference: 1758568 . |
| 1990 |
Cooper,B.J.,Gallagher,E.A.,Smith,C.A.,Valentine,B.A.,Winand,N.J.: :
Mosaic Expression of Dystrophin in Carriers of Canine X-Linked Muscular Dystrophy Laboratory Investigation 62:171-178, 1990. Pubmed reference: 2406503 . |
| 1990 |
Valentine,B.A.,Cooper,B.J.,Cummings,J.F.,Delahunta,A.: :
Canine X-Linked Muscular Dystrophy - Morphologic Lesions Journal of the Neurological Sciences 97:1-23, 1990. Pubmed reference: 2370557 . |
| 1989 |
Valentine,B.A.,Cummings,J.F.,Cooper,B.J.: :
Development of Duchenne-Type Cardiomyopathy - Morphologic Studies in a Canine Model American Journal of Pathology 135:671-678, 1989. Pubmed reference: 2679113 . |
| 1989 |
Valentine,B.A.,Kornegay,J.N.,Cooper,B.J.: :
Clinical Electromyographic Studies of Canine X-Linked Muscular Dystrophy American Journal of Veterinary Research 50:2145-2147, 1989. Pubmed reference: 2610444 . |
| 1988 |
Cooper,B.J.,Valentine,B.A.: :
X-linked muscular dystrophy in the dog. Trends Genet 4:30, 1988. Pubmed reference: 3245071 . |
| 1988 |
Cooper,B.J.,Winand,N.J.,Stedman,H.,Valentine,B.A.,Hoffman,E.P.,Kunkel,L.M.,Scott,M.O.,Fischbeck,K.H.,Kornegay,J.N.,Avery,R.J.,Williams,J.R.,Schmickel,R.D.,Sylvester,J.E.: :
The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs Nature 334:154-156, 1988. Pubmed reference: 3290691 . DOI: 10.1038/334154a0 . |
| 1988 |
Cooper,BJ.,Valentine,BA.,Wilson,S.,Patterson,DF.,Concannon,PW.: :
Canine muscular dystrophy: confirmation of X-linked inheritance. J Hered 79:405-8, 1988. Pubmed reference: 3209849 . |
| 1988 |
Valentine,B.A.,Cooper,B.J.,Delahunta,A.,O'Quinn,R.,Blue,J.T.: :
Canine X-Linked Muscular Dystrophy - An Animal Model of Duchenne Muscular Dystrophy - Clinical Studies Journal of the Neurological Sciences 88:69-81, 1988. Pubmed reference: 3225630 . |
| 1986 |
Valentine,B.A.,Cooper,B.J.,Cummings,J.F.,deLahunta,A.: :
Progressive muscular dystrophy in a golden retriever dog: light microscope and ultrastructural features at 4 and 8 months. Acta Neuropathol 71:301-10, 1986. Pubmed reference: 3799143 . |
| 1985 |
Simpson,S.T.,Braund,K.G.: :
Myotonic dystrophy-like disease in a dog. J Am Vet Med Assoc 186:495-8, 1985. Pubmed reference: 3972711 . |
| 1980 |
Funkquist,B.,Haraldsson,I.,Stahre,L.: :
Primary progressive muscular dystrophy in the dog. Vet Rec 106:341-3, 1980. Pubmed reference: 7376386 . |
| 1974 |
Mason,R.W.: :
Muscular dystrophy in pups. N Z Vet J 22:170-2, 1974. Pubmed reference: 4531607 . DOI: 10.1080/00480169.1974.34159 . |
| 1951 |
Innes,J.R.: :
Myopathies in animals; a record of some cases including progressive muscular dystrophy (pseudo-hypertrophic) (dog), "weisses Fleisch" (lamb), neuropathic muscular atrophy (sheep) and lymphocytic/histiocytic myositis, neuritis, radiculitis (dog). Br Vet J 107:131-43, 1951. Pubmed reference: 14821563 . DOI: 10.1016/s0007-1935(17)52263-0 . |