The detail information of Muscular dystrophy, Duchenne type
OMIA Basic Information
Possible human homologues (MIM numbers):
Mendelian trait/disorder: yes
Mode of inheritance: X-linked recessive
Considered a defect: yes
Year key mutation first reported: 1992
Species-specific name: X-linked muscular dystrophy; Dystrophin-deficient muscular dystrophy
Species-specific symbol: DD-MD
More detail information can see in
Associated Breeds
| iDog Breed Number | Breed Name | Personality | Height | Weight | History | Breed Source |
|---|---|---|---|---|---|---|
| CB67 | Cavalier King Charles Spaniel | 30.5-33 cm | 5.9-8.2 kg | United Kingdom (England) | ||
| CB111 | German Short-Haired Pointer | 58.4-63.5 cm (male), 53.3-58.4 cm (female) | 24.9-31.8 kg (male), 20.4-27.2 kg (female) | Germany | ||
| CB116 | Golden Retriever | 58.4-61 cm (male), 54.6-57.2 cm (female) | 29.5-34 kg (male), 24.9-29.5 kg (female) | United Kingdom (Scotland) | ||
| CB118 | Grand Basset Griffon Vendeen | 39.4-45.7 cm | 18.1-20.4 kg | France | ||
| CB132 | Irish Terrier | 45.7 cm | 12.2 kg (male), 11.3 kg (female) | Ireland | ||
| CB281 | Japanese Spitz | 30-36 cm | 5-11.3 kg | Japan | ||
| CB147 | Labrador Retriever | 57.2-62.2 cm (male), 54.6-59.7 cm (female) | 29.5-36.3 kg (male), 24.9-31.8 kg (female) | Canada, United Kingdom (England) | ||
| CB161 | Miniature Schnauzer | 30.5-35.6 cm | 5-9.1 kg | Germany | ||
| CB179 | Pembroke Welsh Corgi | 25.4-30.5 cm | up to 13.6 kg (male), up to 12.7 kg (female) | United Kingdom(Wales) | ||
| CB202 | American Rat Terrier | 25.4-33 cm (miniature), 33-45.7 cm (standard) | 4.5-11.3 kg | United States | ||
| CB205 | Rottweiler | 61-68.6 cm (male), 55.9-63.5 cm (female) | 49.9-59 kg (male), 34.9-49.9 kg (female) | Germany | ||
| CB210 | Samoyed | 53.3-59.7 cm (male), 48.3-53.3 cm (female) | 20.4-29.5 kg (male), 15.9-22.7 kg (female) | Russia | ||
| CB244 | Tibetan Terrier | 35.6-43.2 cm (male), slightly smaller (female) | 8.2-13.6 kg (male), slightly smaller (female) | Tibet | ||
| CB252 | Weimaraner | 63.5-68.6 cm (male), 58.4-63.5 cm (female) | 31.8-40.8 kg (male), 24.9-34 kg (female) | Germany |
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2021 |
Kupatt,C.,Windisch,A.,Moretti,A.,Wolf,E.,Wurst,W.,Walter,M.C.: :
Genome editing for Duchenne muscular dystrophy: a glimpse of the future? Gene Ther :, 2021. Pubmed reference: 33531685 . DOI: 10.1038/s41434-021-00222-4 . |
| 2021 |
Nitahara-Kasahara,Y.,Kuraoka,M.,Guillermo,P.H.,Hayashita-Kinoh,H.,Maruoka,Y.,Nakamura-Takahasi,A.,Kimura,K.,Takeda,S.,Okada,T.: :
Dental pulp stem cells can improve muscle dysfunction in animal models of Duchenne muscular dystrophy. Stem Cell Res Ther 12:78, 2021. Pubmed reference: 33494794 . DOI: 10.1186/s13287-020-02099-3 . |
| 2021 |
Tone,Y.,Mamchaoui,K.,Tsoumpra,M.K.,Hashimoto,Y.,Terada,R.,Maruyama,R.,Gait,M.J.,Arzumanov,A.A.,McClorey,G.,Imamura,M.,Takeda,S.,Yokota,T.,Wood,M.J.A.,Mouly,V.,Aoki,Y.: :
Immortalized canine dystrophic myoblast cell lines for development of peptide-conjugated splice-switching oligonucleotides. Nucleic Acid Ther 31:172-181, 2021. Pubmed reference: 33567244 . DOI: 10.1089/nat.2020.0907 . |
| 2020 |
Barthélémy,I.,Calmels,N.,Weiss,R.B.,Tiret,L.,Vulin,A.,Wein,N.,Peccate,C.,Drougard,C.,Beroud,C.,Deburgrave,N.,Thibaud,J.L.,Escriou,C.,Punzón,I.,Garcia,L.,Kaplan,J.C.,Flanigan,K.M.,Leturcq,F.,Blot,S.: :
X-linked muscular dystrophy in a Labrador Retriever strain: phenotypic and molecular characterisation. Skelet Muscle 10:23, 2020. Pubmed reference: 32767978 . DOI: 10.1186/s13395-020-00239-0 . |
| 2020 |
Brinkmeyer-Langford,C.,Chu,C.,Balog-Alvarez,C.,Yu,X.,Cai,J.J.,Nabity,M.,Kornegay,J.N.: :
Correction: Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. PLoS One 15:e0236916, 2020. Pubmed reference: 32702009 . DOI: 10.1371/journal.pone.0236916 . |
| 2020 |
Brunetti,B.,Muscatello,L.V.,Letko,A.,Papa,V.,Cenacchi,G.,Grillini,M.,Murgiano,L.,Jagannathan,V.,Drögemüller,C.: :
X-Linked Duchenne-Type Muscular Dystrophy in Jack Russell Terrier Associated with a Partial Deletion of the Canine <i>DMD</i> Gene. Genes (Basel) 11:, 2020. Pubmed reference: 33049940 . DOI: 10.3390/genes11101175 . |
| 2020 |
Story,B.D.,Miller,M.E.,Bradbury,A.M.,Million,E.D.,Duan,D.,Taghian,T.,Faissler,D.,Fernau,D.,Beecy,S.J.,Gray-Edwards,H.L.: :
Canine models of inherited musculoskeletal and neurodegenerative diseases. Front Vet Sci 7:80, 2020. Pubmed reference: 32219101 . DOI: 10.3389/fvets.2020.00080 . |
| 2020 |
Switonski,M.: :
Impact of gene therapy for canine monogenic diseases on the progress of preclinical studies. J Appl Genet :, 2020. Pubmed reference: 32189222 . DOI: 10.1007/s13353-020-00554-8 . |
| 2019 |
Nghiem,P.P.,Kornegay,J.N.: :
Gene therapies in canine models for Duchenne muscular dystrophy. Hum Genet 138:483-489, 2019. Pubmed reference: 30734120 . DOI: 10.1007/s00439-019-01976-z . |
| 2019 |
Wasala,N.B.,Hakim,C.H.,Chen,S.J.,Yang,N.N.,Duan,D.: :
Questions Answered and Unanswered by the First CRISPR Editing Study in a Canine Model of Duchenne Muscular Dystrophy. Hum Gene Ther 30:535-543, 2019. Pubmed reference: 30648435 . DOI: 10.1089/hum.2018.243 . |
| 2018 |
Amoasii,L.,Hildyard,J.C.W.,Li,H.,Sanchez-Ortiz,E.,Mireault,A.,Caballero,D.,Harron,R.,Stathopoulou,T.R.,Massey,C.,Shelton,J.M.,Bassel-Duby,R.,Piercy,R.J.,Olson,E.N.: :
Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Science :, 2018. Pubmed reference: 30166439 . DOI: 10.1126/science.aau1549 . |
| 2018 |
Brinkmeyer-Langford,C.,Chu,C.,Balog-Alvarez,C.,Yu,X.,Cai,J.J.,Nabity,M.,Kornegay,J.N.: :
Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. PLoS One 13:e0194485, 2018. Pubmed reference: 29554127 . DOI: 10.1371/journal.pone.0194485 . |
| 2018 |
Cohen,J.: :
In dogs, CRISPR fixes a muscular dystrophy. Science 361:835, 2018. Pubmed reference: 30166469 . DOI: 10.1126/science.361.6405.835 . |
| 2018 |
Eresen,A.,Alic,L.,Kornegay,J.,Ji,J.X.: :
Assessment of disease severity in a Canine Model of Duchenne Muscular Dystrophy: Classification of Quantitative MRI. Conf Proc IEEE Eng Med Biol Soc 2018:648-651, 2018. Pubmed reference: 30440480 . DOI: 10.1109/EMBC.2018.8512303 . |
| 2018 |
Maruyama,R.,Aoki,Y.,Takeda,S.,Yokota,T.: :
In Vivo Evaluation of Multiple Exon Skipping with Peptide-PMOs in Cardiac and Skeletal Muscles in Dystrophic Dogs. Methods Mol Biol 1828:365-379, 2018. Pubmed reference: 30171554 . DOI: 10.1007/978-1-4939-8651-4_23 . |
| 2018 |
MataLópez,S.,Hammond,J.J.,Rigsby,M.B.,Balog-Alvarez,C.J.,Kornegay,J.N.,Nghiem,P.P.: :
A novel canine model for Duchenne muscular dystrophy (DMD): single nucleotide deletion in DMD gene exon 20. Skelet Muscle 8:16, 2018. Pubmed reference: 29843823 . DOI: 10.1186/s13395-018-0162-1 . |
| 2018 |
Nakamura,A.,Aoki,Y.,Tsoumpra,M.,Yokota,T.,Takeda,S.: :
In Vitro Multiexon Skipping by Antisense PMOs in Dystrophic Dog and Exon 7-Deleted DMD Patient. Methods Mol Biol 1828:151-163, 2018. Pubmed reference: 30171540 . DOI: 10.1007/978-1-4939-8651-4_9 . |
| 2018 |
Shrader,S.M.,Jung,S.,Denney,T.S.,Smith,B.F.: :
Characterization of Australian Labradoodle dystrophinopathy. Neuromuscul Disord 28:927-937, 2018. Pubmed reference: 30286978 . DOI: 10.1016/j.nmd.2018.08.008 . |
| 2018 |
Sánchez,L.,Beltrán,E.,deStefani,A.,Guo,L.T.,Shea,A.,Shelton,G.D.,DeRisio,L.,Burmeister,L.M.: :
Clinical and genetic characterisation of dystrophin-deficient muscular dystrophy in a family of Miniature Poodle dogs. PLoS One 13:e0193372, 2018. Pubmed reference: 29474464 . DOI: 10.1371/journal.pone.0193372 . |
| 2017 |
Kodippili,K.,Hakim,C.,Pan,X.,Yang,H.T.,YUe,Y.,Zhang,Y.,Shin,J.H.,Yang,N.N.,Duan,D.: :
Dual AAV gene therapy for Duchenne muscular dystrophy with a 7-kb mini-dystrophin gene in the canine model. Hum Gene Ther :, 2017. Pubmed reference: 28793798 . DOI: 10.1089/hum.2017.095 . |
| 2017 |
Kornegay,J.N.: :
The golden retriever model of Duchenne muscular dystrophy. Skelet Muscle 7:9, 2017. Pubmed reference: 28526070 . DOI: 10.1186/s13395-017-0124-z . |
| 2017 |
LeGuiner,C.,Servais,L.,Montus,M.,Larcher,T.,Fraysse,B.,Moullec,S.,Allais,M.,François,V.,Dutilleul,M.,Malerba,A.,Koo,T.,Thibaut,J.L.,Matot,B.,Devaux,M.,LeDuff,J.,Deschamps,J.Y.,Barthelemy,I.,Blot,S.,Testault,I.,Wahbi,K.,Ederhy,S.,Martin,S.,Veron,P.,Georger,C.,Athanasopoulos,T.,Masurier,C.,Mingozzi,F.,Carlier,P.,Gjata,B.,Hogrel,J.Y.,Adjali,O.,Mavilio,F.,Voit,T.,Moullier,P.,Dickson,G.: :
Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy. Nat Commun 8:16105, 2017. Pubmed reference: 28742067 . DOI: 10.1038/ncomms16105 . |
| 2017 |
Maruyama,R.,Echigoya,Y.,Caluseriu,O.,Aoki,Y.,Takeda,S.,Yokota,T.: :
Systemic Delivery of Morpholinos to Skip Multiple Exons in a Dog Model of Duchenne Muscular Dystrophy. Methods Mol Biol 1565:201-213, 2017. Pubmed reference: 28364245 . DOI: 10.1007/978-1-4939-6817-6_17 . |
| 2017 |
Nghiem,P.P.,Bello,L.,Stoughton,W.B.,López,S.M.,Vidal,A.H.,Hernandez,B.V.,Hulbert,K.N.,Gourley,T.R.,Bettis,A.K.,Balog-Alvarez,C.J.,Heath-Barnett,H.,Kornegay,J.N.: :
Changes in Muscle Metabolism are Associated with Phenotypic Variability in Golden Retriever Muscular Dystrophy . Yale J Biol Med 90:351-360, 2017. Pubmed reference: 28955176 . |
| 2017 |
VanBelzen,D.J.,Malik,A.S.,Henthorn,P.S.,Kornegay,J.N.,Stedman,H.H.: :
Mechanism of Deletion Removing All Dystrophin Exons in a Canine Model for DMD Implicates Concerted Evolution of X Chromosome Pseudogenes. Mol Ther Methods Clin Dev 4:62-71, 2017. Pubmed reference: 28344992 . DOI: 10.1016/j.omtm.2016.12.001 . |
| 2017 |
Wilson,K.,Faelan,C.,Patterson-Kane,J.C.,Rudmann,D.G.,Moore,S.A.,Frank,D.,Charleston,J.,Tinsley,J.,Young,G.D.,Milici,A.J.: :
Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification. Toxicol Pathol 45:961-976, 2017. Pubmed reference: 28974147 . DOI: 10.1177/0192623317734823 . |
| 2016 |
Acosta,A.R.,VanWie,E.,Stoughton,W.B.,Bettis,A.K.,Barnett,H.H.,LaBrie,N.R.,Balog-Alvarez,C.J.,Nghiem,P.P.,Cummings,K.J.,Kornegay,J.N.: :
Use of the six-minute walk test to characterize golden retriever muscular dystrophy. Neuromuscul Disord :, 2016. Pubmed reference: 27818009 . DOI: 10.1016/j.nmd.2016.09.024 . |
| 2016 |
Brinkmeyer-Langford,C.,Balog-Alvarez,C.,Cai,J.J.,Davis,B.W.,Kornegay,J.N.: :
Genome-wide association study to identify potential genetic modifiers in a canine model for Duchenne muscular dystrophy. BMC Genomics 17:665, 2016. Pubmed reference: 27549615 . DOI: 10.1186/s12864-016-2948-z . |
| 2016 |
Galindo,C.L.,Soslow,J.H.,Brinkmeyer-Langford,C.L.,Gupte,M.,Smith,H.M.,Sengsayadeth,S.,Sawyer,D.B.,Benson,D.W.,Kornegay,J.N.,Markham,L.W.: :
Translating golden retriever muscular dystrophy microarray findings to novel biomarkers for cardiac/skeletal muscle function in Duchenne muscular dystrophy. Pediatr Res 79:629-36, 2016. Pubmed reference: 26672735 . DOI: 10.1038/pr.2015.257 . |
| 2016 |
Gentil,C.,LeGuiner,C.,Falcone,S.,Hogrel,J.Y.,Peccate,C.,Lorain,S.,Benkhelifa-Ziyyat,S.,Guigand,L.,Montus,M.,Servais,L.,Voit,T.,Piétri-Rouxel,F.: :
Dystrophin Threshold Level Necessary for Normalization of Neuronal Nitric Oxide Synthase, Inducible Nitric Oxide Synthase, and Ryanodine Receptor-Calcium Release Channel Type 1 Nitrosylation in Golden Retriever Muscular Dystrophy Dystrophinopathy. Hum Gene Ther :, 2016. Pubmed reference: 27279388 . DOI: 10.1089/hum.2016.041 . |
| 2016 |
Kornegay,J.N.,Bogan,D.J.,Bogan,J.R.,Dow,J.L.,Wang,J.,Fan,Z.,Liu,N.,Warsing,L.C.,Grange,R.W.,Ahn,M.,Balog-Alvarez,C.J.,Cotten,S.W.,Willis,M.S.,Brinkmeyer-Langford,C.,Zhu,H.,Palandra,J.,Morris,C.A.,Styner,M.A.,Wagner,K.R.: :
Dystrophin-deficient dogs with reduced myostatin have unequal muscle growth and greater joint contractures. Skelet Muscle 6:14, 2016. Pubmed reference: 27047655 . DOI: 10.1186/s13395-016-0085-7 . |
| 2016 |
MiskewNichols,B.,Aoki,Y.,Kuraoka,M.,Lee,J.J.,Takeda,S.,Yokota,T.: :
Multi-exon Skipping Using Cocktail Antisense Oligonucleotides in the Canine X-linked Muscular Dystrophy. J Vis Exp :, 2016. Pubmed reference: 27285612 . DOI: 10.3791/53776 . |
| 2016 |
Nghiem,P.P.,Bello,L.,Balog-Alvarez,C.,MataLópez,S.,Bettis,A.,Barnett,H.,Hernandez,B.,Schatzberg,S.J.,Piercy,R.J.,Kornegay,J.N.: :
Whole genome sequencing reveals a 7 base-pair deletion in DMD exon 42 in a dog with muscular dystrophy Mammalian Genome :, 2016. Pubmed reference: 28028563 . DOI: 10.1007/s00335-016-9675-2 . |
| 2016 |
Sitzia,C.,Farini,A.,Jardim,L.,Razini,P.,Belicchi,M.,Cassinelli,L.,Villa,C.,Erratico,S.,Parolini,D.,Bella,P.,CarlosdaSilvaBizario,J.,Garcia,L.,DiasBaruffi,M.,Meregalli,M.,Torrente,Y.: :
Adaptive immune response impairs the efficacy of autologous transplantation of engineered stem cells in dystrophic dogs. Mol Ther :, 2016. Pubmed reference: 27506452 . DOI: 10.1038/mt.2016.163 . |
| 2016 |
Terrill,J.R.,Duong,M.N.,Turner,R.,LeGuiner,C.,Boyatzis,A.,Kettle,A.J.,Grounds,M.D.,Arthur,P.G.: :
Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy. Redox Biol 9:276-286, 2016. Pubmed reference: 27611888 . DOI: 10.1016/j.redox.2016.08.016 . |
| 2015 |
Atencia-Fernandez,S.,Shiel,R.E.,Mooney,C.T.,Nolan,C.M.: :
Muscular dystrophy in the Japanese Spitz: an inversion disrupts the DMD and RPGR genes. Anim Genet 46:175-84, 2015. Pubmed reference: 25644216 . DOI: 10.1111/age.12266 . |
| 2015 |
Duan,D.: :
Duchenne Muscular Dystrophy Gene Therapy in the Canine Model. Hum Gene Ther Clin Dev :, 2015. Pubmed reference: 25710459 . DOI: 10.1089/humc.2015.006 . |
| 2015 |
Duan,D.,Hakim,C.H.,Ambrosio,C.E.,Smith,B.F.,Sweeney,H.L.: :
Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al. Dis Model Mech 8:193-4, 2015. Pubmed reference: 25740329 . DOI: 10.1242/dmm.019216 . |
| 2015 |
Jenkins,C.A.,Forman,O.P.: :
Identification of a novel frameshift mutation in the DMD gene as the cause of muscular dystrophy in a Norfolk terrier dog. Canine Genet Epidemiol 2:7, 2015. Pubmed reference: 26401335 . DOI: 10.1186/s40575-015-0019-4 . |
| 2015 |
Robriquet,F.,Lardenois,A.,Babarit,C.,Larcher,T.,Dubreil,L.,Leroux,I.,Zuber,C.,Ledevin,M.,Deschamps,J.Y.,Fromes,Y.,Cherel,Y.,Guevel,L.,Rouger,K.: :
Differential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell Transplantation. PLoS One 10:e0123336, 2015. Pubmed reference: 25955839 . DOI: 10.1371/journal.pone.0123336 . |
| 2015 |
Vieira,N.M.,Elvers,I.,Alexander,M.S.,Moreira,Y.B.,Eran,A.,Gomes,J.P.,Marshall,J.L.,Karlsson,E.K.,Verjovski-Almeida,S.,Lindblad-Toh,K.,Kunkel,L.M.,Zatz,M.: :
Jagged 1 Rescues the Duchenne Muscular Dystrophy Phenotype. Cell 163:1204-13, 2015. Pubmed reference: 26582133 . DOI: 10.1016/j.cell.2015.10.049 . |
| 2014 |
DeVanna,J.C.,Kornegay,J.N.,Bogan,D.J.,Bogan,J.R.,Dow,J.L.,Hawkins,E.C.: :
Respiratory dysfunction in unsedated dogs with golden retriever muscular dystrophy. Neuromuscul Disord 24:63-73, 2014. Pubmed reference: 24295812 . DOI: 10.1016/j.nmd.2013.10.001 . |
| 2014 |
Martin,P.T.,Golden,B.,Okerblom,J.,Camboni,M.,Chandrasekharan,K.,Xu,R.,Varki,A.,Flanigan,K.M.,Kornegay,J.N.: :
A Comparative Study of N-glycolylneuraminic Acid (Neu5Gc) and Cytotoxic T Cell (CT) Carbohydrate Expression in Normal and Dystrophin-Deficient Dog and Human Skeletal Muscle. PLoS One 9:e88226, 2014. Pubmed reference: 24505439 . DOI: 10.1371/journal.pone.0088226 . |
| 2014 |
Mead,A.F.,Petrov,M.,Malik,A.S.,Mitchell,M.A.,Childers,M.K.,Bogan,J.R.,Seidner,G.,Kornegay,J.N.,Stedman,H.H.: :
Diaphragm Remodeling and Compensatory Respiratory Mechanics in a Canine Model of Duchenne Muscular Dystrophy. J Appl Physiol (1985) :, 2014. Pubmed reference: 24408990 . DOI: 10.1152/japplphysiol.00833.2013 . |
| 2014 |
Peres,M.A.,daRocha,A.M.,Vannucchi,C.I.,Mendes,C.M.,Cavalcanti,P.V.,Nichi,M.,Ambrosio,C.E.,Miglino,M.A.,Visintin,J.A.,D'ÁvilaAssumpção,M.E.: :
Semen analysis of Golden Retriever healthy dogs and those affected by muscular dystrophy. Andrologia 46:277-82, 2014. Pubmed reference: 23463904 . DOI: 10.1111/and.12079 . |
| 2014 |
Wang,Z.,Halbert,C.L.,Lee,D.,Butts,T.,Tapscott,S.J.,Storb,R.,Miller,A.D.: :
Elimination of contaminating cap genes in AAV vector virions reduces immune responses and improves transgene expression in a canine gene therapy model. Gene Ther :, 2014. Pubmed reference: 24500525 . DOI: 10.1038/gt.2014.4 . |
| 2013 |
Araujo,K.P.,Bonuccelli,G.,Duarte,C.N.,Gaiad,T.P.,Moreira,D.F.,Feder,D.,Belizario,J.E.,Miglino,M.A.,Lisanti,M.P.,Ambrosio,C.E.: :
Bortezomib (PS-341) treatment decreases inflammation and partially rescues the expression of the dystrophin-glycoprotein complex in GRMD dogs. PLoS One 8:e61367, 2013. Pubmed reference: 23579193 . DOI: 10.1371/journal.pone.0061367 . |
| 2013 |
Brinkmeyer-Langford,C.,Kornegay,J.N.: :
Comparative Genomics of X-linked Muscular Dystrophies: The Golden Retriever Model. Curr Genomics 14:330-42, 2013. Pubmed reference: 24403852 . DOI: 10.2174/13892029113149990004 . |
| 2013 |
Broeckx,B.J.,Coopman,F.,Verhoeven,G.E.,VanHaeringen,W.,vandeGoor,L.,Bosmans,T.,Gielen,I.,Saunders,J.H.,Soetaert,S.S.,VanBree,H.,VanNeste,C.,VanNieuwerburgh,F.,VanRyssen,B.,Verelst,E.,VanSteendam,K.,Deforce,D.: :
The prevalence of nine genetic disorders in a dog population from Belgium, the Netherlands and Germany. PLoS One 8:e74811, 2013. Pubmed reference: 24069350 . DOI: 10.1371/journal.pone.0074811 . |
| 2013 |
Cotten,S.W.,Kornegay,J.N.,Bogan,D.J.,Wadosky,K.M.,Patterson,C.,Willis,M.S.: :
Genetic myostatin decrease in the golden retriever muscular dystrophy model does not significantly affect the ubiquitin proteasome system despite enhancing the severity of disease. Am J Transl Res 6:43-53, 2013. Pubmed reference: 24349620 . |
| 2013 |
Fan,Z.,Wang,J.,Ahn,M.,Shiloh-Malawsky,Y.,Chahin,N.,Elmore,S.,Bagnell,C.R.,Wilber,K.,An,H.,Lin,W.,Zhu,H.,Styner,M.,Kornegay,J.N.: :
Characteristics of magnetic resonance imaging biomarkers in a natural history study of golden retriever muscular dystrophy. Neuromuscul Disord :, 2013. Pubmed reference: 24295811 . DOI: 10.1016/j.nmd.2013.10.005 . |
| 2013 |
Kane,A.M.,DeFrancesco,T.C.,Boyle,M.C.,Malarkey,D.E.,Ritchey,J.W.,Atkins,C.E.,Cullen,J.M.,Kornegay,J.N.,Keene,B.W.: :
Cardiac structure and function in female carriers of a canine model of Duchenne muscular dystrophy. Res Vet Sci 94:610-7, 2013. Pubmed reference: 23231955 . DOI: 10.1016/j.rvsc.2012.09.027 . |
| 2013 |
Kerwin,W.S.,Naumova,A.,Storb,R.,Tapscott,S.J.,Wang,Z.: :
Mapping contrast agent uptake and retention in MRI studies of myocardial perfusion: case control study of dogs with Duchenne muscular dystrophy. Int J Cardiovasc Imaging 29:819-26, 2013. Pubmed reference: 23070737 . DOI: 10.1007/s10554-012-0137-y . |
| 2013 |
Nghiem,P.P.,Hoffman,E.P.,Mittal,P.,Brown,K.J.,Schatzberg,S.J.,Ghimbovschi,S.,Wang,Z.,Kornegay,J.N.: :
Sparing of the Dystrophin-Deficient Cranial Sartorius Muscle Is Associated with Classical and Novel Hypertrophy Pathways in GRMD Dogs. Am J Pathol 183:1411-24, 2013. Pubmed reference: 24160322 . DOI: 10.1016/j.ajpath.2013.07.013 . |
| 2013 |
Shin,J.H.,Greer,B.,Hakim,C.H.,Zhou,Z.,Chung,Y.C.,Duan,Y.,He,Z.,Duan,D.: :
Quantitative phenotyping of Duchenne muscular dystrophy dogs by comprehensive gait analysis and overnight activity monitoring. PLoS One 8:e59875, 2013. Pubmed reference: 23544107 . DOI: 10.1371/journal.pone.0059875 . |
| 2013 |
Shin,J.H.,Pan,X.,Hakim,C.H.,Yang,H.T.,Yue,Y.,Zhang,K.,Terjung,R.L.,Duan,D.: :
Microdystrophin ameliorates muscular dystrophy in the canine model of duchenne muscular dystrophy. Mol Ther 21:750-7, 2013. Pubmed reference: 23319056 . DOI: 10.1038/mt.2012.283 . |
| 2013 |
Wang,J.,Fan,Z.,Vandenborne,K.,Walter,G.,Shiloh-Malawsky,Y.,An,H.,Kornegay,J.N.,Styner,M.A.: :
A computerized MRI biomarker quantification scheme for a canine model of Duchenne muscular dystrophy. Int J Comput Assist Radiol Surg 8:763-74, 2013. Pubmed reference: 23299128 . DOI: 10.1007/s11548-012-0810-6 . |
| 2013 |
Wuebbles,R.D.,Sarathy,A.,Kornegay,J.N.,Burkin,D.J.: :
Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy. Dis Model Mech 6:1175-84, 2013. Pubmed reference: 23846963 . DOI: 10.1242/dmm.012211 . |
| 2012 |
Barbash,I.M.,Cecchini,S.,Faranesh,A.Z.,Virag,T.,Li,L.,Yang,Y.,Hoyt,R.F.,Kornegay,J.N.,Bogan,J.R.,Garcia,L.,Lederman,R.J.,Kotin,R.M.: :
MRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy. Gene Ther :, 2012. Pubmed reference: 22551778 . DOI: 10.1038/gt.2012.38 . |
| 2012 |
Barthélémy,I.,Uriarte,A.,Drougard,C.,Unterfinger,Y.,Thibaud,J.L.,Blot,S.: :
Effects of an immunosuppressive treatment in the GRMD dog model of Duchenne muscular dystrophy. PLoS One 7:e48478, 2012. Pubmed reference: 23185260 . DOI: 10.1371/journal.pone.0048478 . |
| 2012 |
Bedu,A.S.,Labruyère,J.J.,LaurentThibaud,J.,Barthélémy,I.,Leperlier,D.,Saunders,J.H.,Blot,S.: :
Age-related thoracic radiographic changes in Golden and Labrador Retriever muscular dystrophy Vet Radiol Ultrasound :, 2012. Pubmed reference: 22702494 . DOI: 10.1111/j.1740-8261.2012.01948.x . |
| 2012 |
Cassano,M.,Berardi,E.,Crippa,S.,Toelen,J.,Barthelemy,I.,Micheletti,R.,Chuah,M.,Vanderdriessche,T.,Debyser,Z.,Blot,S.,Sampaolesi,M.: :
Alteration of cardiac progenitor cell potency in GRMD dogs. Cell Transplant :, 2012. Pubmed reference: 22513051 . DOI: 10.3727/096368912X638919 . |
| 2012 |
Kornegay,J.N.,Bogan,J.R.,Bogan,D.J.,Childers,M.K.,Li,J.,Nghiem,P.,Detwiler,D.A.,Larsen,C.A.,Grange,R.W.,Bhavaraju-Sanka,R.K.,Tou,S.,Keene,B.P.,Howard,J.F.,Wang,J.,Fan,Z.,Schatzberg,S.J.,Styner,M.A.,Flanigan,K.M.,Xiao,X.,Hoffman,E.P.: :
Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mamm Genome 23:85-108, 2012. Pubmed reference: 22218699 . DOI: 10.1007/s00335-011-9382-y . |
| 2012 |
Su,J.B.,Cazorla,O.,Blot,S.,Blanchard-Gutton,N.,AitMou,Y.,Barthélémy,I.,Sambin,L.,Sampedrano,C.C.,Gouni,V.,Unterfinger,Y.,Aguilar,P.,Thibaud,J.L.,Bizé,A.,Pouchelon,J.L.,Dabiré,H.,Ghaleh,B.,Berdeaux,A.,Chetboul,V.,Lacampagne,A.,Hittinger,L.: :
Bradykinin restores left ventricular function, sarcomeric protein phosphorylation, and e/nNOS levels in dogs with Duchenne muscular dystrophy cardiomyopathy. Cardiovasc Res 95:86-96, 2012. Pubmed reference: 22562664 . DOI: 10.1093/cvr/cvs161 . |
| 2012 |
Vieira,N.M.,Valadares,M.,Zucconi,E.,Secco,M.,Bueno,C.R.,Brandalise,V.,Assoni,A.,Gomes,J.,Landini,V.,Andrade,T.,Caetano,H.V.,Vainzof,M.,Zatz,M.: :
Human adipose-derived mesenchymal stromal cells injected systemically into GRMD dogs without immunosuppression are able to reach the host muscle and express human dystrophin. Cell Transplant 21:1407-17, 2012. Pubmed reference: 23168016 . DOI: 10.3727/096368911X . |
| 2012 |
Vulin,A.,Barthélémy,I.,Goyenvalle,A.,Thibaud,J.L.,Beley,C.,Griffith,G.,Benchaouir,R.,leHir,M.,Unterfinger,Y.,Lorain,S.,Dreyfus,P.,Voit,T.,Carlier,P.,Blot,S.,Garcia,L.: :
Muscle function recovery in golden retriever muscular dystrophy after AAV1-U7 exon skipping. Mol Ther 20:2120-33, 2012. Pubmed reference: 22968479 . DOI: 10.1038/mt.2012.181 . |
| 2012 |
Wang,Z.,Storb,R.,Halbert,C.L.,Banks,G.B.,Butts,T.M.,Finn,E.E.,Allen,J.M.,Miller,A.D.,Chamberlain,J.S.,Tapscott,S.J.: :
Successful regional delivery and long-term expression of a dystrophin gene in canine muscular dystrophy: a preclinical model for human therapies. Mol Ther 20:1501-7, 2012. Pubmed reference: 22692496 . DOI: 10.1038/mt.2012.111 . |
| 2012 |
Yang,H.T.,Shin,J.H.,Hakim,C.H.,Pan,X.,Terjung,R.L.,Duan,D.: :
Dystrophin deficiency compromises force production of the extensor carpi ulnaris muscle in the canine model of Duchenne muscular dystrophy. PLoS One 7:e44438, 2012. Pubmed reference: 22973449 . DOI: 10.1371/journal.pone.0044438 . |
| 2012 |
Yokota,T.,Nakamura,A.,Nagata,T.,Saito,T.,Kobayashi,M.,Aoki,Y.,Echigoya,Y.,Partridge,T.,Hoffman,E.P.,Takeda,S.: :
Extensive and prolonged restoration of dystrophin expression with vivo-morpholino-mediated multiple exon skipping in dystrophic dogs. Nucleic Acid Ther 22:306-15, 2012. Pubmed reference: 22888777 . DOI: 10.1089/nat.2012.0368 . |
| 2011 |
Guevel,L.,Lavoie,J.R.,Perez-Iratxeta,C.,Rouger,K.,Dubreil,L.,Feron,M.,Talon,S.,Brand,M.,Megeney,L.A.: :
Quantitative proteomic analysis of dystrophic dog muscle. J Proteome Res 10:2465-78, 2011. Pubmed reference: 21410286 . DOI: 10.1021/pr2001385 . |
| 2011 |
Hoffman,E.P.,Bronson,A.,Levin,A.A.,Takeda,S.,Yokota,T.,Baudy,A.R.,Connor,E.M.: :
Restoring dystrophin expression in duchenne muscular dystrophy muscle progress in exon skipping and stop codon read through. Am J Pathol 179:12-22, 2011. Pubmed reference: 21703390 . DOI: 10.1016/j.ajpath.2011.03.050 . |
| 2011 |
Kornegay,JN.,Bogan,JR.,Bogan,DJ.,Childers,MK.,Grange,RW.: :
Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements. Methods Mol Biol 709:105-23, 2011. Pubmed reference: 21194024 . DOI: 10.1007/978-1-61737-982-6_7 . |
| 2011 |
Nakamura,A.,Takeda,S.: :
Mammalian models of Duchenne Muscular Dystrophy: pathological characteristics and therapeutic applications. J Biomed Biotechnol 2011:184393, 2011. Pubmed reference: 21274260 . DOI: 10.1155/2011/184393 . |
| 2011 |
Olby,NJ.,Sharp,NJ.,Nghiem,PE.,Keene,BW.,DeFrancesco,TC.,Sidley,JA.,Kornegay,JN.,Schatzberg,SJ.: :
Clinical progression of X-linked muscular dystrophy in two German Shorthaired Pointers. J Am Vet Med Assoc 238:207-12, 2011. Pubmed reference: 21235374 . DOI: 10.2460/javma.238.2.207 . |
| 2011 |
Smith,BF.,Yue,Y.,Woods,PR.,Kornegay,JN.,Shin,JH.,Williams,RR.,Duan,D.: :
An intronic LINE-1 element insertion in the dystrophin gene aborts dystrophin expression and results in Duchenne-like muscular dystrophy in the corgi breed. Lab Invest 91:216-31, 2011. Pubmed reference: 20714321 . DOI: 10.1038/labinvest.2010.146 . |
| 2011 |
Yokota,T.,Hoffman,E.,Takeda,S.: :
Antisense oligo-mediated multiple exon skipping in a dog model of duchenne muscular dystrophy. Methods Mol Biol 709:299-312, 2011. Pubmed reference: 21194037 . DOI: 10.1007/978-1-61737-982-6_20 . |
| 2010 |
Kornegay,JN.,Li,J.,Bogan,JR.,Bogan,DJ.,Chen,C.,Zheng,H.,Wang,B.,Qiao,C.,Howard,JF.,Xiao,X.: :
Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs. Mol Ther 18:1501-8, 2010. Pubmed reference: 20517298 . DOI: 10.1038/mt.2010.94 . |
| 2010 |
Partridge,T.: :
The potential of exon skipping for treatment for Duchenne muscular dystrophy. J Child Neurol 25:1165-70, 2010. Pubmed reference: 20519674 . DOI: 10.1177/0883073810371130 . |
| 2010 |
Saito,T.,Nakamura,A.,Aoki,Y.,Yokota,T.,Okada,T.,Osawa,M.,Takeda,S.: :
Antisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patient. PLoS One 5:e12239, 2010. Pubmed reference: 20805873 . DOI: 10.1371/journal.pone.0012239 . |
| 2010 |
Walmsley,GL.,Arechavala-Gomeza,V.,Fernandez-Fuente,M.,Burke,MM.,Nagel,N.,Holder,A.,Stanley,R.,Chandler,K.,Marks,SL.,Muntoni,F.,Shelton,GD.,Piercy,RJ.: :
A duchenne muscular dystrophy gene hot spot mutation in dystrophin-deficient cavalier king charles spaniels is amenable to exon 51 skipping. PLoS One 5:e8647, 2010. Pubmed reference: 20072625 . DOI: 10.1371/journal.pone.0008647 . |
| 2010 |
Zucconi,E.,Valadares,MC.,Vieira,NM.,Bueno,CR.,Secco,M.,Jazedje,T.,daSilva,HC.,Vainzof,M.,Zatz,M.: :
Ringo: discordance between the molecular and clinical manifestation in a golden retriever muscular dystrophy dog. Neuromuscul Disord 20:64-70, 2010. Pubmed reference: 19944604 . DOI: 10.1016/j.nmd.2009.10.011 . |
| 2009 |
Piercy,RJ.,Walmsley,G.: :
Muscular dystrophy in Cavalier King Charles spaniels. Vet Rec 165:62, 2009. Pubmed reference: 19596683 . |
| 2009 |
Willmann,R.,Possekel,S.,Dubach-Powell,J.,Meier,T.,Ruegg,MA.: :
Mammalian animal models for Duchenne muscular dystrophy. Neuromuscul Disord 19:241-9, 2009. Pubmed reference: 19217290 . DOI: 10.1016/j.nmd.2008.11.015 . |
| 2009 |
Yokota,T.,Lu,QL.,Partridge,T.,Kobayashi,M.,Nakamura,A.,Takeda,S.,Hoffman,E.: :
Efficacy of systemic morpholino exon-skipping in Duchenne dystrophy dogs. Ann Neurol 65:667-76, 2009. Pubmed reference: 19288467 . DOI: 10.1002/ana.21627 . |
| 2009 |
Zucconi,E.,Jazedje,T.,Valadares,M.C.,Zatz,M.: :
Comments to the paper by Ambrósio CE, Fadel L, Gaiad TP, Martins DS, et al. [Identification of three distinguishable phenotypes in golden retriever muscular dystrophy (Genet. Mol. Res. 2009 Apr 7;8 (2): 389-396)]. Genet Mol Res 8:818-21, 2009. Pubmed reference: 19731203 . DOI: 10.4238/vol8-3gmrCarta01 . |
| 2008 |
Banks,G.B.,Chamberlain,J.S.: :
The value of mammalian models for duchenne muscular dystrophy in developing therapeutic strategies. Curr Top Dev Biol 84:431-53, 2008. Pubmed reference: 19186250 . DOI: 10.1016/S0070-2153(08)00609-1 . |
| 2008 |
Urasawa,N.,Wada,MR.,Machida,N.,Yuasa,K.,Shimatsu,Y.,Wakao,Y.,Yuasa,S.,Sano,T.,Nonaka,I.,Nakamura,A.,Takeda,S.: :
Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. Circulation 117:2437-48, 2008. Pubmed reference: 18458171 . DOI: 10.1161/CIRCULATIONAHA.107.739326 . |
| 2007 |
Smith,B.F.,Kornegay,J.N.,Duan,D.: :
Independent canine models of Duchenne muscular dystrophy due to intronic insertions of repetitive DNA. Mol Ther. 15(Suppl. 1):S51, 2007. |
| 2006 |
McClorey,G.,Moulton,HM.,Iversen,PL.,Fletcher,S.,Wilton,SD.: :
Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD. Gene Ther 13:1373-81, 2006. Pubmed reference: 16724091 . DOI: 10.1038/sj.gt.3302800 . |
| 2005 |
Chetboul,V.,Tessier-Vetzel,D.,Escriou,C.,Tissier,R.,Carlos,C.,Boussouf,M.,Pouchelon,JL.,Blot,S.,Derumeaux,G.: :
Diagnostic potential of natriuretic peptides in the occult phase of golden retriever muscular dystrophy cardiomyopathy. J Vet Intern Med 18:845-50, 2005. Pubmed reference: 15638261 . |
| 2005 |
Nguyen,F.,Guigand,L.,Goubault-Leroux,I.,Wyers,M.,Cherel,Y.: :
Microvessel density in muscles of dogs with golden retriever muscular dystrophy. Neuromuscul Disord 15:154-63, 2005. Pubmed reference: 15694137 . DOI: 10.1016/j.nmd.2004.11.002 . |
| 2005 |
Shelton,GD.,Engvall,E.: :
Canine and feline models of human inherited muscle diseases. Neuromuscul Disord 15:127-38, 2005. Pubmed reference: 15694134 . DOI: 10.1016/j.nmd.2004.10.019 . |
| 2005 |
Shimatsu,Y.,Yoshimura,M.,Yuasa,K.,Urasawa,N.,Tomohiro,M.,Nakura,M.,Tanigawa,M.,Nakamura,A.,Takeda,S.: :
Major clinical and histopathological characteristics of canine X-linked muscular dystrophy in Japan, CXMDJ. Acta Myol 24:145-54, 2005. Pubmed reference: 16550932 . |
| 2004 |
Chetboul,V.,Carlos,C.,Blot,S.,Thibaud,JL.,Escriou,C.,Tissier,R.,Retortillo,JL.,Pouchelon,JL.: :
Tissue Doppler assessment of diastolic and systolic alterations of radial and longitudinal left ventricular motions in Golden Retrievers during the preclinical phase of cardiomyopathy associated with muscular dystrophy. Am J Vet Res 65:1335-41, 2004. Pubmed reference: 15524319 . |
| 2004 |
Chetboul,V.,Escriou,C.,Tessier,D.,Richard,V.,Pouchelon,JL.,Thibault,H.,Lallemand,F.,Thuillez,C.,Blot,S.,Derumeaux,G.: :
Tissue Doppler imaging detects early asymptomatic myocardial abnormalities in a dog model of Duchenne's cardiomyopathy. Eur Heart J 25:1934-9, 2004. Pubmed reference: 15522464 . DOI: 10.1016/j.ehj.2004.08.013 . |
| 2004 |
Dell'Agnola,C.,Wang,Z.,Storb,R.,Tapscott,SJ.,Kuhr,CS.,Hauschka,SD.,Lee,RS.,Sale,GE.,Zellmer,E.,Gisburne,S.,Bogan,J.,Kornegay,JN.,Cooper,BJ.,Gooley,TA.,Little,MT.: :
Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs. Blood 104:4311-8, 2004. Pubmed reference: 15328150 . DOI: 10.1182/blood-2004-06-2247 . |
| 2004 |
Jones,B.R.,Brennan,S.,Mooney,C.T.,Callanan,J.J.,McAllister,H.,Guo,L.T.,Martin,P.T.,Engvall,E.,Shelton,G.D.: :
Muscular dystrophy with truncated dystrophin in a family of Japanese Spitz dogs. J Neurol Sci 217:143-9, 2004. Pubmed reference: 14706216 . |
| 2004 |
Liu,JM.,Okamura,CS.,Bogan,DJ.,Bogan,JR.,Childers,MK.,Kornegay,JN.: :
Effects of prednisone in canine muscular dystrophy. Muscle Nerve 30:767-73, 2004. Pubmed reference: 15468337 . DOI: 10.1002/mus.20154 . |
| 2004 |
Shelton,G.D.: :
Muscular dystrophies: expanding our knowledge in companion animals. Vet J 168:6-8, 2004. Pubmed reference: 15158202 . DOI: 10.1016/j.tvjl.2004.03.013 . |
| 2003 |
Cerletti,M.,Negri,T.,Cozzi,F.,Colpo,R.,Andreetta,F.,Croci,D.,Davies,K.E.,Cornelio,F.,Pozza,O.,Karpati,G.,Gilbert,R.,Mora,M.: :
Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer Gene Therapy 10:750-7, 2003. Pubmed reference: 12704413 . DOI: 10.1038/sj.gt.3301941 . |
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Collins,C.A.,Morgan,J.E.: :
Duchenne's muscular dystrophy: animal models used to investigate pathogenesis and develop therapeutic strategies. Int J Exp Pathol 84:165-72, 2003. Pubmed reference: 14632630 . |
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Kornegay,J.N.,Cundiff,D.D.,Bogan,D.J.,Bogan,J.R.,Okamura,C.S.: :
The cranial sartorius muscle undergoes true hypertrophy in dogs with golden retriever muscular dystrophy Neuromuscular Disorders 13:493-500, 2003. Pubmed reference: 12899877 . |
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Shimatsu,Y.,Katagiri,K.,Furuta,T.,Nakura,M.,Tanioka,Y.,Yuasa,K.,Tomohiro,M.,Kornegay,J.N.,Nonaka,I.,Takeda,S.: :
Canine X-linked muscular dystrophy in Japan (CXMDJ) Experimental Animals 52:93-7, 2003. Pubmed reference: 12806883 . |
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Bergman,R.L.,Inzana,K.D.,Monroe,W.E.,Shell,L.G.,Liu,L.A.,Engvall,E.,Shelton,G.D.: :
Dystrophin-deficient muscular dystrophy in a labrador retriever Journal of the American Animal Hospital Association 38:255-261, 2002. Pubmed reference: 12022412 . |
| 2002 |
Childers,M.K.,Okamura,C.S.,Bogan,D.J.,Bogan,J.R.,Petroski,G.F.,McDonald,K.,Kornegay,J.N.: :
Eccentric contraction injury in dystrophic canine muscle Archives of Physical Medicine & Rehabilitation 83:1572-1578, 2002. |
| 2002 |
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[Animal models of Duchenne muscular dystrophy]. Rev Prat 52:937-40, 2002. Pubmed reference: 12063758 . |
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Nguyen,F.,Cherel,Y.,Guigand,L.,Goubault-Leroux,I.,Wyers,M.: :
Muscle lesions associated with dystrophin deficiency in neonatal golden retriever puppies Journal of Comparative Pathology 126:100-108, 2002. Pubmed reference: 11944998 . DOI: 10.1053/jcpa.2001.0526 . |
| 2002 |
Passerini,L.,Bernasconi,P.,Baggi,F.,Confalonieri,P.,Cozzi,F.,Cornelio,F.,Mantegazza,R.: :
Fibrogenic cytokines and extent of fibrosis in muscle of dogs with X-linked golden retriever muscular dystrophy Neuromuscular Disorders 12:828-835, 2002. Pubmed reference: 12398833 . |
| 2002 |
Shelton,G.D.,Engvall,E.: :
Muscular dystrophies and other inherited myopathies. Vet Clin North Am Small Anim Pract 32:103-24, 2002. Pubmed reference: 11785725 . |
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Childers,M.K.,Okamura,C.S.,Bogan,D.J.,Bogan,J.R.,Sullivan,M.J.,Kornegay,J.N.: :
Myofiber injury and regeneration in a canine homologue of Duchenne muscular dystrophy American Journal of Physical Medicine & Rehabilitation 80:175-181, 2001. Pubmed reference: 11237271 . |
| 2001 |
Cozzi,F.,Cerletti,M.,Luvoni,G.C.,Lombardo,R.,Brambilla,P.G.,Faverzani,S.,Blasevich,F.,Cornelio,F.,Pozza,O.,Mora,M.: :
Development of muscle pathology in canine X-linked muscular dystrophy. II. Quantitative characterization of histopathological progression during postnatal skeletal muscle development Acta Neuropathologica 101:469-478, 2001. Pubmed reference: 11484818 . |
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Fletcher,S.,Carville,K.S.,Howell,J.M.,Mann,C.J.,Wilton,S.D.: :
Evaluation of a short interspersed nucleotide element in the 3 ' untranslated region of the defective dystrophin gene of dogs with muscular dystrophy American Journal of Veterinary Research 62:1964-1968, 2001. Pubmed reference: 11763189 . |
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Fletcher,S.,Ly,T.,Duff,R.M.,Howell,J.M.,Wilton,S.D.: :
Cryptic splicing involving the splice site mutation in the canine model of Duchenne muscular dystrophy Neuromuscular Disorders 11:239-243, 2001. Pubmed reference: 11297938 . |
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Bartlett,R.J.,Stockinger,S.,Denis,M.M.,Bartlett,W.T.,Inverardi,L.,Le,T.T.,Man,N.T.,Morris,G.E.,Bogan,D.J.,Metcalf-Bogan,J.,Kornegay,J.N.: :
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide Nature Biotechnology 18:615-622, 2000. Pubmed reference: 10835598 . DOI: 10.1038/76448 . |
| 2000 |
Bartlett,R.J.,Stockinger,S.,Denis,M.M.,Bartlett,W.T.,Inverardi,L.,Le,T.T.,Man,T.M.,Morris,G.E.,Bogan,D.J.,Metcalf-Bogan,J.,Kornegay,J.N.: :
In vivo targeted repair of a point mutation in the canine dystrophin gene by a chimeric RNA/DNA oligonucleotide (vol 18, pg 615, 2000) Nature Biotechnology 18:1209, 2000. DOI: 10.1038/81216 . |
| 2000 |
Wetterman,C.A.,Harkin,K.R.,Cash,W.C.,Nietfield,J.C.,Shelton,G.D.: :
Hypertrophic muscular dystrophy in a young dog Journal of the American Veterinary Medical Association 216:878-+, 2000. |
| 1999 |
Honeyman,K.,Carville,K.S.,Howell,J.M.,Fletcher,S.,Wilton,S.D.: :
Development of a snapback method of single-strand conformation polymorphism analysis for genotyping Golden Retrievers for the X-linked muscular dystrophy allele American Journal of Veterinary Research 60:734-737, 1999. Pubmed reference: 10376903 . |
| 1999 |
Kornegay,J.N.,Bogan,D.J.,Bogan,J.R.,Childers,M.K.,Cundiff,D.D.,Petroski,G.F.,Schueler,R.O.: :
Contraction force generated by tarsal joint flexion and extension in dogs with golden retriever muscular dystrophy Journal of the Neurological Sciences 166:115-121, 1999. Pubmed reference: 10475104 . |
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Lanfossi,M.,Cozzi,F.,Bugini,D.,Colombo,S.,Scarpa,P.,Morandi,L.,Galbiati,S.,Cornelio,F.,Pozza,O.,Mora,M.: :
Development of muscle pathology in canine X-linked muscular dystrophy. I. Delayed postnatal maturation of affected and normal muscle as revealed by myosin isoform analysis and utrophin expression Acta Neuropathologica 97:127-138, 1999. Pubmed reference: 9928823 . |
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Molecular analysis of a spontaneous dystrophin 'knockout' dog Neuromuscular Disorders 9:289-295, 1999. Pubmed reference: 10407848 . |
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A polymerase chain reaction screening strategy for the promoter of the canine dystrophin gene American Journal of Veterinary Research 60:1040-1046, 1999. Pubmed reference: 10490068 . |
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| 1992 |
Sharp,N.J.H.,Kornegay,J.N.,Vancamp,S.D.,Herbstreith,M.H.,Secore,S.L.,Kettle,S.,Hung,W.Y.,Constantinou,C.D.,Dykstra,M.J.,Roses,A.D.,Bartlett,R.J.: :
An Error in Dystrophin Messenger RNA Processing in Golden Retriever Muscular Dystrophy, an Animal Homologue of Duchenne Muscular Dystrophy Genomics 13:115-121, 1992. Pubmed reference: 1577476 . |
| 1992 |
Valentine,B.A.,Winand,N.J.,Pradhan,D.,Moise,N.S.,Delahunta,A.,Kornegay,J.N.,Cooper,B.J.: :
Canine X-Linked Muscular Dystrophy as an Animal Model of Duchenne Muscular Dystrophy - A Review American Journal of Medical Genetics 42:352-356, 1992. Pubmed reference: 1536178 . DOI: 10.1002/ajmg.1320420320 . |
| 1991 |
Moise,NS.,Valentine,BA.,Brown,CA.,Erb,HN.,Beck,KA.,Cooper,BJ.,Gilmour,RF.: :
Duchenne's cardiomyopathy in a canine model: electrocardiographic and echocardiographic studies. J Am Coll Cardiol 17:812-20, 1991. Pubmed reference: 1825214 . |
| 1991 |
Partridge,T.: :
Animal models of muscular dystrophy--what can they teach us? Neuropathol Appl Neurobiol 17:353-63, 1991. Pubmed reference: 1758568 . |
| 1990 |
Valentine,B.A.,Cooper,B.J.,Cummings,J.F.,Delahunta,A.: :
Canine X-Linked Muscular Dystrophy - Morphologic Lesions Journal of the Neurological Sciences 97:1-23, 1990. Pubmed reference: 2370557 . |
| 1988 |
Cooper,B.J.,Valentine,B.A.: :
X-linked muscular dystrophy in the dog. Trends Genet 4:30, 1988. Pubmed reference: 3245071 . |
| 1988 |
Cooper,B.J.,Winand,N.J.,Stedman,H.,Valentine,B.A.,Hoffman,E.P.,Kunkel,L.M.,Scott,M.O.,Fischbeck,K.H.,Kornegay,J.N.,Avery,R.J.,Williams,J.R.,Schmickel,R.D.,Sylvester,J.E.: :
The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs Nature 334:154-156, 1988. Pubmed reference: 3290691 . DOI: 10.1038/334154a0 . |
| 1988 |
Cooper,BJ.,Valentine,BA.,Wilson,S.,Patterson,DF.,Concannon,PW.: :
Canine muscular dystrophy: confirmation of X-linked inheritance. J Hered 79:405-8, 1988. Pubmed reference: 3209849 . |
| 1988 |
Valentine,B.A.,Cooper,B.J.,Delahunta,A.,O'Quinn,R.,Blue,J.T.: :
Canine X-Linked Muscular Dystrophy - An Animal Model of Duchenne Muscular Dystrophy - Clinical Studies Journal of the Neurological Sciences 88:69-81, 1988. Pubmed reference: 3225630 . |
| 1986 |
Valentine,B.A.,Cooper,B.J.,Cummings,J.F.,deLahunta,A.: :
Progressive muscular dystrophy in a golden retriever dog: light microscope and ultrastructural features at 4 and 8 months. Acta Neuropathol 71:301-10, 1986. Pubmed reference: 3799143 . |
| 1985 |
Simpson,S.T.,Braund,K.G.: :
Myotonic dystrophy-like disease in a dog. J Am Vet Med Assoc 186:495-8, 1985. Pubmed reference: 3972711 . |
| 1980 |
Funkquist,B.,Haraldsson,I.,Stahre,L.: :
Primary progressive muscular dystrophy in the dog. Vet Rec 106:341-3, 1980. Pubmed reference: 7376386 . |
| 1974 |
Mason,R.W.: :
Muscular dystrophy in pups. N Z Vet J 22:170-2, 1974. Pubmed reference: 4531607 . DOI: 10.1080/00480169.1974.34159 . |
| 1951 |
Innes,J.R.: :
Myopathies in animals; a record of some cases including progressive muscular dystrophy (pseudo-hypertrophic) (dog), "weisses Fleisch" (lamb), neuropathic muscular atrophy (sheep) and lymphocytic/histiocytic myositis, neuritis, radiculitis (dog). Br Vet J 107:131-43, 1951. Pubmed reference: 14821563 . DOI: 10.1016/s0007-1935(17)52263-0 . |