The detail information of Immunoglobulin A deficiency
OMIA Basic Information

Possible human homologues (MIM numbers): -

Mendelian trait/disorder: unknown

Mode of inheritance: -

Considered a defect: yes

Year key mutation first reported: -

Species-specific name: -

Species-specific symbol: -

More detail information can see in

Associated Breeds
iDog Breed Number Breed Name Personality Height Weight History Breed Source
CB73 Chinese Shar-Pei 45.7-50.8 cm 20.4-27.2 kg China
CB110 German Shepherd Dog 61-66 cm (male), 55.9-61 cm (female) 29.5-40.8 kg (male), 22.7-31.8 kg (female) Germany
CB116 Golden Retriever 58.4-61 cm (male), 54.6-57.2 cm (female) 29.5-34 kg (male), 24.9-29.5 kg (female) United Kingdom (Scotland)
CB147 Labrador Retriever 57.2-62.2 cm (male), 54.6-59.7 cm (female) 29.5-36.3 kg (male), 24.9-31.8 kg (female) Canada, United Kingdom (England)
Associated Gene
There are no associated genes.
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2019 Ellis,J.A.: :
Canine IgA and IgA deficiency: Implications for immunization against respiratory pathogens. Can Vet J 60:1305-1311, 2019.
Pubmed reference: 31814637 .
2015 Olsson,M.,Tengvall,K.,Frankowiack,M.,Kierczak,M.,Bergvall,K.,Axelsson,E.,Tintle,L.,Marti,E.,Roosje,P.,Leeb,T.,Hedhammar,Å.,Hammarström,L.,Lindblad-Toh,K.: :
Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency. PLoS One 10:e0133844, 2015.
Pubmed reference: 26225558 . DOI: 10.1371/journal.pone.0133844 .
2014 Olsson,M.,Frankowiack,M.,Tengvall,K.,Roosje,P.,Fall,T.,Ivansson,E.,Bergvall,K.,Hansson-Hamlin,H.,Sundberg,K.,Hedhammar,A.,Lindblad-Toh,K.,Hammarström,L.: :
The dog as a genetic model for immunoglobulin A (IgA) deficiency: identification of several breeds with low serum IgA concentrations. Vet Immunol Immunopathol 160:255-9, 2014.
Pubmed reference: 24935667 . DOI: 10.1016/j.vetimm.2014.05.010 .
2013 Frankowiack,M.,Hellman,L.,Zhao,Y.,Arnemo,J.M.,Lin,M.,Tengvall,K.,Møller,T.,Lindblad-Toh,K.,Hammarström,L.: :
IgA deficiency in wolves. Dev Comp Immunol 40:180-4, 2013.
Pubmed reference: 23352622 . DOI: 10.1016/j.dci.2013.01.005 .
2003 Norris,C.R.,Gershwin,L.J.: :
Evaluation of systemic and secretory IgA concentrations and immunohistochemical stains for IgA-containing B cells in mucosal tissues of an Irish setter with selective IgA deficiency Journal of the American Animal Hospital Association 39:247-50, 2003.
Pubmed reference: 12755197 .
1996 Tipold,A.,Pfister,H.,Jungi,T.W.: :
IgA-deficiency in the dog [German] Praktische Tierarzt 77:181 ff., 1996.
1992 Mansfield,L.S.,Schad,G.A.: :
Strongyloides-stercoralis Infection in IgA-Deficient Dogs American Journal of Tropical Medicine and Hygiene 47:830-836, 1992.
Pubmed reference: 1471742 .
1991 Campbell,K.L.,Neitzel,C.,Zuckermann,F.A.: :
Immunoglobulin-A Deficiency in the Dog Canine Practice 16:7-11, 1991.