| Symbol |
CERS2
|
| Desciption |
ceramide synthase 2
|
| Species |
|
| Location |
chr1:
100153397-100163025(+) |
| Type of Gene |
protein_coding
|
| HGNC |
VGNC:70946
|
| Gene ID | Gene Symbol | Dataset ID | Comparision Group | Regulation Detail | logFC | P Value |
|---|
Gene ID | Gene Symbol | Dataset ID | Comparision Group | Regulation Detail | logFC | P Value |
|---|---|---|---|---|---|---|
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Bx_vs_Cells | down | -0.612 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Bx_vs_Fat | down | -0.799 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Bx_vs_FatS10 | down | -0.550 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Bx_vs_Skim10m | down | -0.781 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Cells_vs_Fat | down | -0.187 | 0.002 |
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Fat_vs_FatS10 | up | 0.249 | 0.003 |
| ENSMMUG00000023234 | CERS2 | PRJNA214874_mmul | Fat_vs_FatsS10 | up | 0.521 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA312819_mmul | Control_Day_vs_Pineal_Dawn | up | 1.289 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA312819_mmul | Control_Day_vs_Pineal_Day | up | 1.037 | 0.000 |
| ENSMMUG00000023234 | CERS2 | PRJNA312819_mmul | Control_Day_vs_Pineal_Dusk | up | 0.970 | 0.000 |
| Gene ID | Gene Symbol | Project ID | Comparision Group | Different Methylation | chromosome | DMR Start | DMR End | DMR Location |
|---|---|---|---|---|---|---|---|---|
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_2CellEmbryoVSMul_8CellEmbryo | -0.651 | chr1 | 100189115 | 100189233 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_2CellEmbryoVSMul_8CellEmbryo | 0.526 | chr1 | 100109068 | 100109184 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_2CellEmbryoVSMul_8CellEmbryo | -0.601 | chr1 | 100152388 | 100152483 | Promoter |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_2CellEmbryoVSMul_8CellEmbryo | -0.651 | chr1 | 100189115 | 100189233 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_8CellEmbryoVSMul_Morula_Embryo | 0.577 | chr1 | 100152304 | 100152453 | Promoter |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_Morula_EmbryoVSMul_ICMofBlastocysts_Embryo | 0.742 | chr1 | 100119232 | 100119571 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_Morula_EmbryoVSMul_ICMofBlastocysts_Embryo | 0.532 | chr1 | 100150608 | 100150672 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_Morula_EmbryoVSMul_ICMofBlastocysts_Embryo | 0.742 | chr1 | 100119232 | 100119571 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_Morula_EmbryoVSMul_ICMofBlastocysts_Embryo | 0.532 | chr1 | 100150437 | 100150672 | Distal Intergenic |
| ENSMMUG00000023234 | CERS2 | PRJNA257664 | Mul_Morula_EmbryoVSMul_ICMofBlastocysts_Embryo | 0.517 | chr1 | 100155712 | 100155801 | Intron |
| GO Term ID | GO Term Name | GO Term Definition |
|---|---|---|
| GO:0003677 | DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| GO:0005634 | nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| GO:0005783 | endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| GO:0005789 | endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| GO:0006629 | lipid metabolic process | The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
| Organism | Gene ID | Gene Name |
|---|---|---|
| Homo sapiens | ENSG00000143418 | CERS2 |
| Callithrix jacchus | ENSCJAG00000007043 | CERS2 |
| Macaca mulatta | ENSMMUG00000023234 | CERS2 |
| Macaca fascicularis | ENSMFAG00000038604 | CERS2 |
| Papio anubis | ENSPANG00000012293 | CERS2 |
| Pan troglodytes | ENSPTRG00000001268 | CERS2 |
| VarID | Species | Type | Position | Allele Frequency | MAF | Genotype Frequency | Consequence Type|Effect | Gene | Transcript | Protein |
|---|
VarID | Species |
Type
|
Position
|
Allele
Frequency
|
MAF
|
Genotype
Frequency
|
Consequence
Type|Effect
|
Gene
|
Transcript
|
Protein
|
|---|---|---|---|---|---|---|---|---|---|---|
| mmu34825728 | macaca mulatta | snp | 1:100148404_100148404 | A:0.0357(15) T:0.2190(92) C:0.7452(313) | T:0.2190 | C|C:0.6000(126) T|T:0.0952(20) T|A:0.0048(1)T|C:0.2429(51)A|A:0.0095(2)C|A:0.0476(10) | upstream_gene_variant|MODIFIER upstream_gene_variant|MODIFIER upstream_gene_variant|MODIFIER upstream_gene_variant|MODIFIER | ENSMMUG00000023234 ENSMMUG00000023234 ENSMMUG00000023231 ENSMMUG00000023231 | ENSMMUT00000046070 ENSMMUT00000046070 ENSMMUT00000032679 ENSMMUT00000032679 | ENSMMUP00000039111 ENSMMUP00000039111 ENSMMUP00000030579 ENSMMUP00000030579 |
| mmu34825729 | macaca mulatta | snp | 1:100148430_100148430 | T:0.0762(32) C:0.9238(388) | T:0.0762 | C|C:0.8714(183) T|T:0.0238(5)C|T:0.1048(22) | upstream_gene_variant|MODIFIER upstream_gene_variant|MODIFIER | ENSMMUG00000023234 ENSMMUG00000023231 | ENSMMUT00000046070 ENSMMUT00000032679 | ENSMMUP00000039111 ENSMMUP00000030579 |
| mmu86835638 | macaca mulatta | indel | 1:100148473_100148473 | A:0.9833(411) AG:0.0167(7) | AG:0.0167 | AG|AG:0.0048(1) A|AG:0.0239(5)A|A:0.9713(203) | upstream_gene_variant|MODIFIER upstream_gene_variant|MODIFIER | ENSMMUG00000023231 ENSMMUG00000023234 | ENSMMUT00000032679 ENSMMUT00000046070 | ENSMMUP00000030579 ENSMMUP00000039111 |
| mmu86835639 | macaca mulatta | indel | 1:100148710_100148712 | CAG:0.9858(416) C:0.0142(6) | C:0.0142 | C|C:0.0047(1) CAG|C:0.0190(4)CAG|CAG:0.9763(206) | upstream_gene_variant|MODIFIER upstream_gene_variant|MODIFIER | ENSMMUG00000023234 ENSMMUG00000023231 | ENSMMUT00000046070 ENSMMUT00000032679 | ENSMMUP00000039111 ENSMMUP00000030579 |
| mcf1617678 | macaca fascicularis | snp | 1:99601355_99601355 | A:0.4231(11) C:0.5769(15) | A:0.4231 | C|C:0.5385(7) A|A:0.3846(5)A|C:0.0769(1) | intron_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSMFAG00000038604 ENSMFAG00000038604 ENSMFAG00000042328 ENSMFAG00000042328 ENSMFAG00000042328 | ENSMFAT00000012761 ENSMFAT00000012759 ENSMFAT00000004577 ENSMFAT00000083491 ENSMFAT00000004564 | ENSMFAP00000038506 ENSMFAP00000038504 ENSMFAP00000030372 ENSMFAP00000057326 ENSMFAP00000030359 |
| mcf1617679 | macaca fascicularis | snp | 1:99601444_99601444 | A:0.8824(30) G:0.1176(4) | G:0.1176 | A|G:0.2353(4) A|A:0.7647(13) | missense_variant|MODERATE missense_variant|MODERATE downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSMFAG00000038604 ENSMFAG00000038604 ENSMFAG00000042328 ENSMFAG00000042328 ENSMFAG00000042328 | ENSMFAT00000012761 ENSMFAT00000012759 ENSMFAT00000004577 ENSMFAT00000083491 ENSMFAT00000004564 | ENSMFAP00000038506 ENSMFAP00000038504 ENSMFAP00000030372 ENSMFAP00000057326 ENSMFAP00000030359 |
| mcf45693444 | macaca fascicularis | indel | 1:99602233_99602234 | TC:0.9706(33) T:0.0294(1) | T:0.0294 | TC|TC:0.9412(16) TC|T:0.0588(1) | intron_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSMFAG00000038604 ENSMFAG00000038604 ENSMFAG00000042328 ENSMFAG00000042328 ENSMFAG00000042328 | ENSMFAT00000012761 ENSMFAT00000012759 ENSMFAT00000004577 ENSMFAT00000083491 ENSMFAT00000004564 | ENSMFAP00000038506 ENSMFAP00000038504 ENSMFAP00000030372 ENSMFAP00000057326 ENSMFAP00000030359 |
| mcf45693445 | macaca fascicularis | indel | 1:99603612_99603613 | T:0.0294(1) TG:0.9706(33) | T:0.0294 | TG|T:0.0588(1) TG|TG:0.9412(16) | 3_prime_UTR_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSMFAG00000038604 ENSMFAG00000038604 ENSMFAG00000042328 ENSMFAG00000042328 ENSMFAG00000042328 | ENSMFAT00000012759 ENSMFAT00000012761 ENSMFAT00000004577 ENSMFAT00000083491 ENSMFAT00000004564 | ENSMFAP00000038504 ENSMFAP00000038506 ENSMFAP00000030372 ENSMFAP00000057326 ENSMFAP00000030359 |
| cjc11771443 | callithrix jacchus | snp | 18:4338793_4338793 | G:1.0000(32) | - | G|G:1.0000(16) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSCJAG00000006972 ENSCJAG00000007043 | ENSCJAT00000013764 ENSCJAT00000013835 | ENSCJAP00000013057 ENSCJAP00000013125 |
| cjc11771444 | callithrix jacchus | snp | 18:4338798_4338798 | T:1.0000(32) | - | T|T:1.0000(16) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSCJAG00000006972 ENSCJAG00000007043 | ENSCJAT00000013764 ENSCJAT00000013835 | ENSCJAP00000013057 ENSCJAP00000013125 |
| cjc15475177 | callithrix jacchus | indel | 18:4338753_4338755 | T:0.0312(1) TAC:0.9688(31) | T:0.0312 | TAC|T:0.0625(1) TAC|TAC:0.9375(15) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSCJAG00000006972 ENSCJAG00000007043 | ENSCJAT00000013764 ENSCJAT00000013835 | ENSCJAP00000013057 ENSCJAP00000013125 |
| cjc15475178 | callithrix jacchus | indel | 18:4338799_4338801 | CAG:0.9688(31) C:0.0312(1) | C:0.0312 | CAG|C:0.0625(1) CAG|CAG:0.9375(15) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSCJAG00000006972 ENSCJAG00000007043 | ENSCJAT00000013764 ENSCJAT00000013835 | ENSCJAP00000013057 ENSCJAP00000013125 |
| panu16356019 | papio anubis | snp | 1:121471048_121471048 | T:0.9898(194) C:0.0102(2) | C:0.0102 | T|T:0.9796(96) T|C:0.0204(2) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPANG00000020214 ENSPANG00000012293 | ENSPANT00000028310 ENSPANT00000022837 | ENSPANP00000003982 ENSPANP00000009127 |
| panu16356020 | papio anubis | snp | 1:121471078_121471078 | A:0.8187(149) G:0.1813(33) | G:0.1813 | G|G:0.0769(7) A|G:0.2088(19)A|A:0.7143(65) | downstream_gene_variant|MODIFIER intron_variant|MODIFIER | ENSPANG00000012293 ENSPANG00000020214 | ENSPANT00000022837 ENSPANT00000028310 | ENSPANP00000009127 ENSPANP00000003982 |
| panu41926968 | papio anubis | indel | 1:121471170_121471170 | CAAA:0.0206(4) C:0.9794(190) | CAAA:0.0206 | C|CAAA:0.0412(4) C|C:0.9588(93) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPANG00000020214 ENSPANG00000012293 | ENSPANT00000028310 ENSPANT00000022837 | ENSPANP00000003982 ENSPANP00000009127 |
| panu41926969 | papio anubis | indel | 1:121471227_121471227 | CT:0.0150(3) C:0.9850(197) | CT:0.0150 | C|C:0.9700(97) C|CT:0.0300(3) | intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPANG00000020214 ENSPANG00000012293 | ENSPANT00000028310 ENSPANT00000022837 | ENSPANP00000003982 ENSPANP00000009127 |
| ptr1105593 | pan troglodytes | snp | 1:128914059_128914059 | A:0.1923(5) G:0.8077(21) | A:0.1923 | G|G:0.6923(9) A|A:0.0769(1)G|A:0.2308(3) | intron_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPTRG00000001267 ENSPTRG00000001267 ENSPTRG00000001268 | ENSPTRT00000002349 ENSPTRT00000100027 ENSPTRT00000084995 | ENSPTRP00000051798 ENSPTRP00000088144 ENSPTRP00000088014 |
| ptr1105594 | pan troglodytes | snp | 1:128914452_128914452 | A:0.2500(6) G:0.7500(18) | A:0.2500 | G|G:0.5833(7) A|A:0.0833(1)G|A:0.3333(4) | intron_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPTRG00000001267 ENSPTRG00000001267 ENSPTRG00000001268 ENSPTRG00000001268 | ENSPTRT00000002349 ENSPTRT00000100027 ENSPTRT00000084995 ENSPTRT00000042983 | ENSPTRP00000051798 ENSPTRP00000088144 ENSPTRP00000088014 ENSPTRP00000040517 |
| ptr22824639 | pan troglodytes | indel | 1:128914325_128914325 | A:0.7083(17) ACT:0.2917(7) | ACT:0.2917 | ACT|ACT:0.1667(2) A|ACT:0.2500(3)A|A:0.5833(7) | intron_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPTRG00000001267 ENSPTRG00000001267 ENSPTRG00000001268 | ENSPTRT00000002349 ENSPTRT00000100027 ENSPTRT00000084995 | ENSPTRP00000051798 ENSPTRP00000088144 ENSPTRP00000088014 |
| ptr22824640 | pan troglodytes | indel | 1:128914338_128914338 | C:0.7083(17) CA:0.2917(7) | CA:0.2917 | C|C:0.5000(6) CA|CA:0.0833(1)C|CA:0.4167(5) | intron_variant|MODIFIER intron_variant|MODIFIER downstream_gene_variant|MODIFIER | ENSPTRG00000001267 ENSPTRG00000001267 ENSPTRG00000001268 | ENSPTRT00000002349 ENSPTRT00000100027 ENSPTRT00000084995 | ENSPTRP00000051798 ENSPTRP00000088144 ENSPTRP00000088014 |