LncExpDB

Version 2.0

Expression Database of Human Long non-coding RNAs

Introduction

LncExpDB is a comprehensive database for lncRNA expression. It covers expression profiles of lncRNA genes across various biological contexts, predicts potential functional lncRNAs and their interacting partners, and thus provides essential guidance on experimental design.

LncExpDB currently houses expression profiles of 101,293 high-quality human lncRNA genes derived from 2,662 samples of 374 biological conditions across 15 biological contexts. Consequently, LncExpDB estimates lncRNA genes’ expression reliability and capacities, identifies 39,253 featured genes, and further obtains 35,188,816 lncRNA-mRNA interactions.

Examples:  HSALNG0134930;  TUG1;  HSALNT0276950;  ENST00000602393.1;  NONHSAT119666.2;  HOTAIRM1:4;  MSTRG.7221.4;  CHS.35608.18; 

Resources

Immunotherapy NEW

140 samples, 4 projects
970 featured genes

Aging NEW

91 samples, 3 projects
1,394 featured genes

Metabolic Disease NEW

231 saplmes, 3 projects
5,439 featured genes

Neurodegenerative Disease NEW

56 samples, 3 projects
2,312 featured genes

Reproduction NEW

147 samples, 1 project
7,823 featured genes

Wound Healing NEW

20 saplmes, 1 project
11,057 featured genes

Normal Tissue/Cell Line

232 samples, 2 projects
7,498 featured genes

Organ Development

313 samples, 1 project
7,922 featured genes

Preimplantation Embryo

125 samples, 2 projects
4,343 featured genes

Cell Differentiation

297 samples, 1 project
1,232 featured genes

Subcellular Localization

36 samples, 1 project
5,292 featured genes

Exosome

97 samples, 2 projects
1,538 featured genes

Cancer Cell Line

658 samples, 1 project
2,907 featured genes

Virus Infection

66 samples, 2 projects
985 featured genes

Circadian Rhythm

153 samples, 1 project
1,740 featured genes

Publications

  • LncExpDB: an expression database of human long non-coding RNAs. Nucleic Acids Res 2021. [PMID=33045751]

    • Related publications:
  • Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021. Nucleic Acids Res 2021. [PMID=33175170]

    • Related Resources

  • LncBook
  • LncRNAWiki
  • LGC

    • News and Update

    06/30/2025 - version 2.0

    • Three new biological contexts: "Neurodegenerative Disease", "Reproduction", and "Wound Healing" introduced.
    • Newly added tools for functional enrichment analysis and visualization.

    09/10/2024 - Update

    • Three new biological contexts: "Immunotherapy Response", "Aging", and "Metabolic Diseases" introduced.
    • "Pipeline" module to share commands and parameters used for lncRNA expression profiling analysis for users' reference.

    08/14/2020 - version 1.0

    • Added reference gene model, expression profiles, and co-expression matrix to the Downloads page.

    Last update: July 2025 (version 2.0)