LncExpDB

Version 2.0

Expression Database of Human Long non-coding RNAs

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  • Contexts
  • Metabolic Disease

    • The LncExpDB Metabolic Disease module focuses on collecting differentially expressed genes in Disease and Healthy groups.

    • Click on the Overview Chart in Expression Levels to get an overview of the expression levels of the corresponding lncRNA across multiple datasets.
    • H, M, L, NE are used to represent lncRNA expression Levels. For specifics, please refer to Help > 2.5
    • Use the filter on the right to identify genes with disease-specific expression levels: High (H), Medium (M), or Low (L).
    • Filter results by entering keywords in the Search box at the top right of the Table.
    Gene ID Gene Symbol Hypertension Metabolically Healthy Obesity Metabolically Unhealthy Obesity Type II Diabetes Chart
    Healthy Disease Healthy Disease Healthy Disease Healthy Disease
    • Click on the Volcano plot in Featured Genes to obtain the volcano plot for each dataset, along with the highlighted corresponding lncRNA.
    • Use the filter on the right to find up- or down-regulated lncRNAs across various Disease Types.
    • Click on the button in the Up / Down column to view gene expression in the healthy / disease group in the corresponding tissue / organ, linear fit to age and functional annotation based on lncRNA-mRNA interactions (based on the Gene Ontology).
    • Filter results by entering keywords in the Search box at the top right of the Table.

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    Gene ID Gene Symbol Hypertension Metabolically Healthy Obesity Metabolically Unhealthy Obesity Type II Diabetes Volcano plot
    P.adj LogFC Up / Down P.adj LogFC Up / Down P.adj LogFC Up / Down P.adj LogFC Up / Down

    Interaction

    • By clicking the tab of “Interactions”, you can select specific datasets of interest and browse the cis or trans interactions between lncRNAs and mRNAs.
    • Moreover, user can select a specific group of interaction by custom thresholds or search the related interactions by lncRNA/protein-coding id or symbol.
    Filter Criteria:
    LncRNA ID LncRNA Symbol LncRNA Location PCG ID PCG Symbol PCG Location R P value Distance