Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000175 | 3'-5'-RNA exonuclease activity | MF |
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004518 | nuclease activity | MF |
| GO:0004527 | exonuclease activity | MF |
| GO:0004532 | exoribonuclease activity | MF |
| GO:0004540 | ribonuclease activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005739 | mitochondrion | CC |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0006725 | cellular aromatic compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0008408 | 3'-5' exonuclease activity | MF |
| GO:0009987 | cellular process | BP |
| GO:0016070 | RNA metabolic process | BP |
| GO:0016787 | hydrolase activity | MF |
| GO:0016788 | hydrolase activity, acting on ester bonds | MF |
| GO:0016796 | exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | MF |
| GO:0016896 | RNA exonuclease activity, producing 5'-phosphomonoesters | MF |
| GO:0034641 | cellular nitrogen compound metabolic process | BP |
| GO:0043170 | macromolecule metabolic process | BP |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0046483 | heterocycle metabolic process | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0090304 | nucleic acid metabolic process | BP |
| GO:0090305 | nucleic acid phosphodiester bond hydrolysis | BP |
| GO:0090501 | RNA phosphodiester bond hydrolysis | BP |
| GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic | BP |
| GO:0140098 | catalytic activity, acting on RNA | MF |
| GO:1901360 | organic cyclic compound metabolic process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map03008 | Ribosome biogenesis in eukaryotes | Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage. |