PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	Pop_G07G052201 View in Genome Browser
Position	chrG07:10128511-10139010 (-) 10499bp
Gene Type	gene
Gene Description (Protein Product)	DNA polymerase
Organism	Populus alba x Populus glandulosa
Also AS	Potri.007G045300AT5G67100Potri.007G045300.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	Pop_G15G049171 Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses Pop_G09G011704 DNA polymerase epsilon subunit Pop_G19G009491 DNA polymerase delta subunit
Regulatory gene	Pop_A01G003924 Zinc finger protein Pop_A01G004096 transcriptional regulator Pop_A01G004283 ZINC FINGER protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000228	nuclear chromosome	CC
GO:0000428	DNA-directed RNA polymerase complex	CC
GO:0000726	obsolete non-recombinational repair	BP
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0003887	DNA-directed DNA polymerase activity	MF
GO:0003896	DNA primase activity	MF
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005657	replication fork	CC
GO:0005658	alpha DNA polymerase:primase complex	CC
GO:0005694	chromosome	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006260	DNA replication	BP
GO:0006261	DNA-templated DNA replication	BP
GO:0006269	DNA replication, synthesis of RNA primer	BP
GO:0006270	DNA replication initiation	BP
GO:0006271	DNA strand elongation involved in DNA replication	BP
GO:0006272	leading strand elongation	BP
GO:0006273	lagging strand elongation	BP
GO:0006281	DNA repair	BP
GO:0006302	double-strand break repair	BP
GO:0006303	double-strand break repair via nonhomologous end joining	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0007275	multicellular organism development	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009058	biosynthetic process	BP
GO:0009059	macromolecule biosynthetic process	BP
GO:0009653	anatomical structure morphogenesis	BP
GO:0009965	leaf morphogenesis	BP
GO:0009987	cellular process	BP
GO:0010016	shoot system morphogenesis	BP
GO:0016070	RNA metabolic process	BP
GO:0016740	transferase activity	MF
GO:0016772	transferase activity, transferring phosphorus-containing groups	MF
GO:0016779	nucleotidyltransferase activity	MF
GO:0018130	heterocycle biosynthetic process	BP
GO:0019438	aromatic compound biosynthetic process	BP
GO:0022616	DNA strand elongation	BP
GO:0030880	RNA polymerase complex	CC
GO:0030894	replisome	CC
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0032774	RNA biosynthetic process	BP
GO:0032991	protein-containing complex	CC
GO:0032993	protein-DNA complex	CC
GO:0033554	cellular response to stress	BP
GO:0034061	DNA polymerase activity	MF
GO:0034062	5'-3' RNA polymerase activity	MF
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034645	cellular macromolecule biosynthetic process	BP
GO:0034654	nucleobase-containing compound biosynthetic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043596	nuclear replication fork	CC
GO:0043601	nuclear replisome	CC
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044271	cellular nitrogen compound biosynthetic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044427	obsolete chromosomal part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044454	obsolete nuclear chromosome part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0048366	leaf development	BP
GO:0048367	shoot system development	BP
GO:0048731	system development	BP
GO:0048827	phyllome development	BP
GO:0048856	anatomical structure development	BP
GO:0050896	response to stimulus	BP
GO:0051716	cellular response to stimulus	BP
GO:0055029	nuclear DNA-directed RNA polymerase complex	CC
GO:0061695	transferase complex, transferring phosphorus-containing groups	CC
GO:0070013	intracellular organelle lumen	CC
GO:0071704	organic substance metabolic process	BP
GO:0071897	DNA biosynthetic process	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0097747	RNA polymerase activity	MF
GO:0099402	plant organ development	BP
GO:0140097	catalytic activity, acting on DNA	MF
GO:0140098	catalytic activity, acting on RNA	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901362	organic cyclic compound biosynthetic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1902494	catalytic complex	CC
GO:1905392	plant organ morphogenesis	BP
GO:1990234	transferase complex	CC

KEGG Term	Name	Description
map03030	DNA replication	A complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (DnaB or MCM complex) precedes the DNA synthetic machinery and unwinds the duplex parental DNA in cooperation with the SSB or RPA. On the leading strand, replication occurs continuously in a 5 to 3 direction, whereas on the lagging strand, DNA replication occurs discontinuously by synthesis and joining of short Okazaki fragments. In prokaryotes, the leading strand replication apparatus consists of a DNA polymerase (pol III core), a sliding clamp (beta), and a clamp loader (gamma delta complex). The DNA primase (DnaG) is needed to form RNA primers. Normally, during replication of the lagging-strand DNA template, an RNA primer is removed either by an RNase H or by the 5 to 3 exonuclease activity of DNA pol I, and the DNA ligase joins the Okazaki fragments. In eukaryotes, three DNA polymerases (alpha, delta, and epsilon) have been identified. DNA primase forms a permanent complex with DNA polymerase alpha. PCNA and RFC function as a clamp and a clamp loader. FEN 1 and RNase H1 remove the RNA from the Okazaki fragments and DNA ligase I joins the DNA.