Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004721 | phosphoprotein phosphatase activity | MF |
| GO:0004722 | protein serine/threonine phosphatase activity | MF |
| GO:0006464 | protein modification process | BP |
| GO:0006470 | protein dephosphorylation | BP |
| GO:0006793 | phosphorus metabolic process | BP |
| GO:0006796 | phosphate-containing compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0010817 | regulation of hormone levels | BP |
| GO:0016311 | dephosphorylation | BP |
| GO:0016787 | hydrolase activity | MF |
| GO:0016788 | hydrolase activity, acting on ester bonds | MF |
| GO:0016791 | phosphatase activity | MF |
| GO:0019538 | protein metabolic process | BP |
| GO:0032879 | regulation of localization | BP |
| GO:0036211 | protein modification process | BP |
| GO:0042578 | phosphoric ester hydrolase activity | MF |
| GO:0043170 | macromolecule metabolic process | BP |
| GO:0043412 | macromolecule modification | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044260 | cellular macromolecule metabolic process | BP |
| GO:0044267 | protein metabolic process | BP |
| GO:0050789 | regulation of biological process | BP |
| GO:0051049 | regulation of transport | BP |
| GO:0065007 | biological regulation | BP |
| GO:0065008 | regulation of biological quality | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0140096 | catalytic activity, acting on a protein | MF |
| GO:1901564 | organonitrogen compound metabolic process | BP |
| GO:2000012 | regulation of auxin polar transport | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map03015 | mRNA surveillance pathway | The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins. |

