PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	Pop_G13G071183 View in Genome Browser
Position	chrG13:12932548-12935898 (+) 3350bp
Gene Type	gene
Gene Description (Protein Product)	Mevalonate
Organism	Populus alba x Populus glandulosa
Also AS	Potri.013G024000AT5G27450Potri.013G024000.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	Pop_G15G017307 Cycloeucalenol Pop_G19G007489 Isopentenyl-diphosphate Delta-isomerase Pop_G18G070822 Belongs to the GPI family
Regulatory gene	Pop_A01G003796 isoform X1 Pop_A01G003952 transcription factor Pop_A01G004056 dnaJ homolog subfamily C member

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000166	nucleotide binding	MF
GO:0000287	magnesium ion binding	MF
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004496	mevalonate kinase activity	MF
GO:0005488	binding	MF
GO:0005524	ATP binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0006084	acetyl-CoA metabolic process	BP
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006163	purine nucleotide metabolic process	BP
GO:0006629	lipid metabolic process	BP
GO:0006637	acyl-CoA metabolic process	BP
GO:0006644	phospholipid metabolic process	BP
GO:0006720	isoprenoid metabolic process	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006732	obsolete coenzyme metabolic process	BP
GO:0006753	nucleoside phosphate metabolic process	BP
GO:0006790	sulfur compound metabolic process	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008144	obsolete drug binding	MF
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008202	steroid metabolic process	BP
GO:0008299	isoprenoid biosynthetic process	BP
GO:0008610	lipid biosynthetic process	BP
GO:0008654	phospholipid biosynthetic process	BP
GO:0009058	biosynthetic process	BP
GO:0009117	nucleotide metabolic process	BP
GO:0009150	purine ribonucleotide metabolic process	BP
GO:0009240	isopentenyl diphosphate biosynthetic process	BP
GO:0009259	ribonucleotide metabolic process	BP
GO:0009987	cellular process	BP
GO:0016125	sterol metabolic process	BP
GO:0016301	kinase activity	MF
GO:0016310	phosphorylation	BP
GO:0016740	transferase activity	MF
GO:0016772	transferase activity, transferring phosphorus-containing groups	MF
GO:0016773	phosphotransferase activity, alcohol group as acceptor	MF
GO:0017076	purine nucleotide binding	MF
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	BP
GO:0019637	organophosphate metabolic process	BP
GO:0019693	ribose phosphate metabolic process	BP
GO:0030554	adenyl nucleotide binding	MF
GO:0032553	ribonucleotide binding	MF
GO:0032555	purine ribonucleotide binding	MF
GO:0032559	adenyl ribonucleotide binding	MF
GO:0033865	nucleoside bisphosphate metabolic process	BP
GO:0033875	ribonucleoside bisphosphate metabolic process	BP
GO:0034032	purine nucleoside bisphosphate metabolic process	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0035383	thioester metabolic process	BP
GO:0035639	purine ribonucleoside triphosphate binding	MF
GO:0036094	small molecule binding	MF
GO:0043167	ion binding	MF
GO:0043168	anion binding	MF
GO:0043169	cation binding	MF
GO:0043603	amide metabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044255	cellular lipid metabolic process	BP
GO:0044281	small molecule metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0046490	isopentenyl diphosphate metabolic process	BP
GO:0046872	metal ion binding	MF
GO:0051186	obsolete cofactor metabolic process	BP
GO:0055086	nucleobase-containing small molecule metabolic process	BP
GO:0071704	organic substance metabolic process	BP
GO:0072521	purine-containing compound metabolic process	BP
GO:0090407	organophosphate biosynthetic process	BP
GO:0097159	organic cyclic compound binding	MF
GO:0097367	carbohydrate derivative binding	MF
GO:1901135	carbohydrate derivative metabolic process	BP
GO:1901265	nucleoside phosphate binding	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1901615	organic hydroxy compound metabolic process	BP

KEGG Term	Name	Description
map04146	Peroxisome	Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.
map01110	Biosynthesis of secondary metabolites	-
map01100	Metabolic pathways	-
map00900	Terpenoid backbone biosynthesis	Terpenoids, also known as isoprenoids, are a large class of natural products consisting of isoprene (C5) units. There are two biosynthetic pathways, the mevalonate pathway [MD:M00095] and the non-mevalonate pathway or the MEP/DOXP pathway [MD:M00096], for the terpenoid building blocks: isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). The action of prenyltransferases then generates higher-order building blocks: geranyl diphosphate (GPP), farsenyl diphosphate (FPP), and geranylgeranyl diphosphate (GGPP), which are the precursors of monoterpenoids (C10), sesquiterpenoids (C15), and diterpenoids (C20), respectively. Condensation of these building blocks gives rise to the precursors of sterols (C30) and carotenoids (C40). The MEP/DOXP pathway is absent in higher animals and fungi, but in green plants the MEP/DOXP and mevalonate pathways co-exist in separate cellular compartments. The MEP/DOXP pathway, operating in the plastids, is responsible for the formation of essential oil monoterpenes and linalyl acetate, some sesquiterpenes, diterpenes, and carotenoids and phytol. The mevalonate pathway, operating in the cytosol, gives rise to triterpenes, sterols, and most sesquiterpenes.