PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	Pop_G16G016432 View in Genome Browser
Position	chrG16:9467702-9469018 (+) 1316bp
Gene Type	gene
Gene Description (Protein Product)	ras GTPase-activating protein-binding protein
Organism	Populus alba x Populus glandulosa
Also AS	Potri.008G096700AT1G26370Potri.008G096700.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	Pop_G17G086968 Helicase associated domain (HA2) Add an annotation Pop_G19G021877 RNA helicase Pop_UnG002472 Superkiller viralicidic activity 2-like
Regulatory gene	Pop_A01G003796 isoform X1 Pop_A01G003952 transcription factor Pop_A01G004056 dnaJ homolog subfamily C member

Load All Networks

Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0000375	RNA splicing, via transesterification reactions	BP
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	BP
GO:0000398	mRNA splicing, via spliceosome	BP
GO:0000932	P-body	CC
GO:0001654	eye development	BP
GO:0001736	establishment of planar polarity	BP
GO:0001738	morphogenesis of a polarized epithelium	BP
GO:0001745	compound eye morphogenesis	BP
GO:0001751	compound eye photoreceptor cell differentiation	BP
GO:0001752	compound eye photoreceptor fate commitment	BP
GO:0001754	eye photoreceptor cell differentiation	BP
GO:0002009	morphogenesis of an epithelium	BP
GO:0002064	epithelial cell development	BP
GO:0002065	columnar/cuboidal epithelial cell differentiation	BP
GO:0002066	columnar/cuboidal epithelial cell development	BP
GO:0003002	regionalization	BP
GO:0003006	developmental process involved in reproduction	BP
GO:0003674	molecular_function	MF
GO:0003676	nucleic acid binding	MF
GO:0003678	DNA helicase activity	MF
GO:0003723	RNA binding	MF
GO:0003724	RNA helicase activity	MF
GO:0003729	mRNA binding	MF
GO:0003824	catalytic activity	MF
GO:0004003	DNA helicase activity	MF
GO:0004004	RNA helicase activity	MF
GO:0004386	helicase activity	MF
GO:0005198	structural molecule activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006355	regulation of DNA-templated transcription	BP
GO:0006396	RNA processing	BP
GO:0006397	mRNA processing	BP
GO:0006464	protein modification process	BP
GO:0006508	proteolysis	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006914	autophagy	BP
GO:0006996	organelle organization	BP
GO:0007154	cell communication	BP
GO:0007163	establishment or maintenance of cell polarity	BP
GO:0007164	establishment of tissue polarity	BP
GO:0007165	signal transduction	BP
GO:0007253	cytoplasmic sequestering of NF-kappaB	BP
GO:0007264	small GTPase mediated signal transduction	BP
GO:0007265	Ras protein signal transduction	BP
GO:0007275	multicellular organism development	BP
GO:0007276	gamete generation	BP
GO:0007281	germ cell development	BP
GO:0007292	female gamete generation	BP
GO:0007389	pattern specification process	BP
GO:0007399	nervous system development	BP
GO:0007423	sensory organ development	BP
GO:0008026	helicase activity	MF
GO:0008069	dorsal/ventral axis specification, ovarian follicular epithelium	BP
GO:0008094	ATP-dependent activity, acting on DNA	MF
GO:0008104	protein localization	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008186	ATP-dependent activity, acting on RNA	MF
GO:0008380	RNA splicing	BP
GO:0009056	catabolic process	BP
GO:0009653	anatomical structure morphogenesis	BP
GO:0009798	axis specification	BP
GO:0009887	animal organ morphogenesis	BP
GO:0009888	tissue development	BP
GO:0009889	regulation of biosynthetic process	BP
GO:0009893	positive regulation of metabolic process	BP
GO:0009950	dorsal/ventral axis specification	BP
GO:0009953	dorsal/ventral pattern formation	BP
GO:0009966	regulation of signal transduction	BP
GO:0009968	negative regulation of signal transduction	BP
GO:0009987	cellular process	BP
GO:0010467	gene expression	BP
GO:0010468	regulation of gene expression	BP
GO:0010494	cytoplasmic stress granule	CC
GO:0010556	regulation of macromolecule biosynthetic process	BP
GO:0010604	positive regulation of macromolecule metabolic process	BP
GO:0010628	positive regulation of gene expression	BP
GO:0010646	regulation of cell communication	BP
GO:0010648	negative regulation of cell communication	BP
GO:0016043	cellular component organization	BP
GO:0016070	RNA metabolic process	BP
GO:0016071	mRNA metabolic process	BP
GO:0016236	macroautophagy	BP
GO:0016318	ommatidial rotation	BP
GO:0016333	morphogenesis of follicular epithelium	BP
GO:0016334	establishment or maintenance of polarity of follicular epithelium	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016579	protein deubiquitination	BP
GO:0016787	hydrolase activity	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0016887	ATP hydrolysis activity	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0019219	regulation of nucleobase-containing compound metabolic process	BP
GO:0019222	regulation of metabolic process	BP
GO:0019538	protein metabolic process	BP
GO:0019953	sexual reproduction	BP
GO:0022008	neurogenesis	BP
GO:0022412	cellular process involved in reproduction in multicellular organism	BP
GO:0022414	reproductive process	BP
GO:0022607	cellular component assembly	BP
GO:0022613	ribonucleoprotein complex biogenesis	BP
GO:0022618	ribonucleoprotein complex assembly	BP
GO:0023051	regulation of signaling	BP
GO:0023052	signaling	BP
GO:0023057	negative regulation of signaling	BP
GO:0030111	regulation of Wnt signaling pathway	BP
GO:0030154	cell differentiation	BP
GO:0030159	signaling receptor complex adaptor activity	MF
GO:0030178	negative regulation of Wnt signaling pathway	BP
GO:0030182	neuron differentiation	BP
GO:0030707	follicle cell of egg chamber development	BP
GO:0030855	epithelial cell differentiation	BP
GO:0031323	regulation of cellular metabolic process	BP
GO:0031326	regulation of cellular biosynthetic process	BP
GO:0032088	negative regulation of NF-kappaB transcription factor activity	BP
GO:0032386	regulation of intracellular transport	BP
GO:0032392	DNA geometric change	BP
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0032504	multicellular organism reproduction	BP
GO:0032508	DNA duplex unwinding	BP
GO:0032879	regulation of localization	BP
GO:0032947	molecular adaptor activity	MF
GO:0032991	protein-containing complex	CC
GO:0033036	macromolecule localization	BP
GO:0034063	stress granule assembly	BP
GO:0034517	ribophagy	BP
GO:0034622	protein-containing complex assembly	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0035556	intracellular signal transduction	BP
GO:0035770	ribonucleoprotein granule	CC
GO:0035973	aggrephagy	BP
GO:0036211	protein modification process	BP
GO:0036464	cytoplasmic ribonucleoprotein granule	CC
GO:0040008	regulation of growth	BP
GO:0042067	establishment of ommatidial planar polarity	BP
GO:0042623	ATP hydrolysis activity	MF
GO:0042706	eye photoreceptor cell fate commitment	BP
GO:0042994	cytoplasmic sequestering of transcription factor	BP
GO:0043021	ribonucleoprotein complex binding	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043412	macromolecule modification	BP
GO:0043433	negative regulation of DNA-binding transcription factor activity	BP
GO:0043933	protein-containing complex organization	BP
GO:0044085	cellular component biogenesis	BP
GO:0044092	negative regulation of molecular function	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0044703	multi-organism reproductive process	BP
GO:0044877	protein-containing complex binding	MF
GO:0045165	cell fate commitment	BP
GO:0045185	maintenance of protein location	BP
GO:0045570	regulation of imaginal disc growth	BP
GO:0045571	negative regulation of imaginal disc growth	BP
GO:0045926	negative regulation of growth	BP
GO:0046483	heterocycle metabolic process	BP
GO:0046530	photoreceptor cell differentiation	BP
GO:0046552	photoreceptor cell fate commitment	BP
GO:0046620	regulation of organ growth	BP
GO:0046621	negative regulation of organ growth	BP
GO:0048468	cell development	BP
GO:0048477	oogenesis	BP
GO:0048513	animal organ development	BP
GO:0048518	positive regulation of biological process	BP
GO:0048519	negative regulation of biological process	BP
GO:0048523	negative regulation of cellular process	BP
GO:0048583	regulation of response to stimulus	BP
GO:0048585	negative regulation of response to stimulus	BP
GO:0048592	eye morphogenesis	BP
GO:0048609	multicellular organismal reproductive process	BP
GO:0048638	regulation of developmental growth	BP
GO:0048640	negative regulation of developmental growth	BP
GO:0048663	neuron fate commitment	BP
GO:0048699	generation of neurons	BP
GO:0048729	tissue morphogenesis	BP
GO:0048731	system development	BP
GO:0048749	compound eye development	BP
GO:0048856	anatomical structure development	BP
GO:0048869	cellular developmental process	BP
GO:0050789	regulation of biological process	BP
GO:0050793	regulation of developmental process	BP
GO:0050794	regulation of cellular process	BP
GO:0050896	response to stimulus	BP
GO:0051049	regulation of transport	BP
GO:0051090	regulation of DNA-binding transcription factor activity	BP
GO:0051093	negative regulation of developmental process	BP
GO:0051171	regulation of nitrogen compound metabolic process	BP
GO:0051179	localization	BP
GO:0051220	cytoplasmic sequestering of protein	BP
GO:0051235	maintenance of location	BP
GO:0051239	regulation of multicellular organismal process	BP
GO:0051241	negative regulation of multicellular organismal process	BP
GO:0051252	regulation of RNA metabolic process	BP
GO:0051276	chromosome organization	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051716	cellular response to stimulus	BP
GO:0060255	regulation of macromolecule metabolic process	BP
GO:0060341	regulation of cellular localization	BP
GO:0060429	epithelium development	BP
GO:0060627	regulation of vesicle-mediated transport	BP
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	BP
GO:0060828	regulation of canonical Wnt signaling pathway	BP
GO:0061912	selective autophagy	BP
GO:0061919	process utilizing autophagic mechanism	BP
GO:0065003	protein-containing complex assembly	BP
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0065009	regulation of molecular function	BP
GO:0070035	obsolete purine NTP-dependent helicase activity	MF
GO:0070646	protein modification by small protein removal	BP
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0070925	organelle assembly	BP
GO:0071103	DNA conformation change	BP
GO:0071704	organic substance metabolic process	BP
GO:0071826	ribonucleoprotein complex subunit organization	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0080090	regulation of primary metabolic process	BP
GO:0090090	negative regulation of canonical Wnt signaling pathway	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090596	sensory organ morphogenesis	BP
GO:0097159	organic cyclic compound binding	MF
GO:0140097	catalytic activity, acting on DNA	MF
GO:0140098	catalytic activity, acting on RNA	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:1903506	regulation of nucleic acid-templated transcription	BP
GO:1905538	polysome binding	MF
GO:1990861	Ubp3-Bre5 deubiquitination complex	CC
GO:1990904	ribonucleoprotein complex	CC
GO:2000026	regulation of multicellular organismal development	BP
GO:2000112	regulation of cellular macromolecule biosynthetic process	BP
GO:2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER	BP
GO:2001141	regulation of RNA biosynthetic process	BP

KEGG Term	Name	Description
map03015	mRNA surveillance pathway	The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins.
map03013	RNA transport	RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation.