PPGR - Gene Detail

Basic Information

Gene ID	Pop_UnG005365 View in Genome Browser
Position	tig00000100_0_45770:39092-39807 (-) 715bp
Gene Type	gene
Gene Description (Protein Product)	E3 ubiquitin-protein ligase
Organism	Populus alba x Populus glandulosa
Also AS	Potri.002G110500AT1G55860Potri.002G110500.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

Pop_UnG086347 DNA damage-binding protein

Pop_UnG036143 DNA damage-binding protein

Pop_UnG036139 DNA damage-binding protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004842	ubiquitin-protein transferase activity	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005737	cytoplasm	CC
GO:0005739	mitochondrion	CC
GO:0005829	cytosol	CC
GO:0006464	protein modification process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009987	cellular process	BP
GO:0016567	protein ubiquitination	BP
GO:0016740	transferase activity	MF
GO:0019538	protein metabolic process	BP
GO:0019787	ubiquitin-like protein transferase activity	MF
GO:0032446	protein modification by small protein conjugation	BP
GO:0036211	protein modification process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043412	macromolecule modification	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0061630	ubiquitin protein ligase activity	MF
GO:0061659	ubiquitin-like protein ligase activity	MF
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0071704	organic substance metabolic process	BP
GO:0140096	catalytic activity, acting on a protein	MF
GO:1901564	organonitrogen compound metabolic process	BP

KEGG Term	Name	Description
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.