Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
AALBA5B827178
Position
aalba5_s00011221:18919-20213 (+)
1294bp
Gene Type
gene
Gene Description (Protein Product)
DNA mismatch repair
Organism
Abies alba
Also AS AT4G25540

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
AALBA5B962490 This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand
AALBA5B933289 Rad4 beta-hairpin domain 3
AALBA5B886445 Rad4 beta-hairpin domain 3
Regulatory gene
AALBA5B001463 Myb family transcription factor APL
AALBA5B002813 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
AALBA5B023305 dof zinc finger protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000217 DNA secondary structure binding MF
GO:0000404 heteroduplex DNA loop binding MF
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003684 damaged DNA binding MF
GO:0003690 double-stranded DNA binding MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006298 mismatch repair BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0008094 ATP-dependent activity, acting on DNA MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009987 cellular process BP
GO:0016043 cellular component organization BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0030983 mismatched DNA binding MF
GO:0032135 DNA insertion or deletion binding MF
GO:0032300 mismatch repair complex CC
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0042623 ATP hydrolysis activity MF
GO:0043170 macromolecule metabolic process BP
GO:0043570 maintenance of DNA repeat elements BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0050896 response to stimulus BP
GO:0051276 chromosome organization BP
GO:0051716 cellular response to stimulus BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1990391 DNA repair complex CC
KEGG Term Name Description
map03430 Mismatch repair DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.