Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
EVM0024719
View in Genome Browser
Position
GWHASIS00000114:15861383-15866677 (-)
5294bp
Gene Type
gene
Gene Description (Protein Product)
E3 ubiquitin-protein ligase
Organism
Acer catalpifolium
Also AS AT3G07370

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
EVM0030661 ubiquitin-40S ribosomal protein
EVM0027144 ubiquitin-40S ribosomal protein
EVM0034983 Serine threonine-protein phosphatase 2A 65 kDa regulatory subunit A
Regulatory gene
EVM0001315 transcription factor that promotes early floral meristem identity in synergy with APETALA1; FRUITFULL and LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Seems to be partially redundant to the function of APETALA1
EVM0003629 MADS-box protein
EVM0005245 MADS-box protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0001101 response to acid chemical BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004842 ubiquitin-protein transferase activity MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0006464 protein modification process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006970 response to osmotic stress BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009266 response to temperature stimulus BP
GO:0009628 response to abiotic stimulus BP
GO:0009651 response to salt stress BP
GO:0009719 response to endogenous stimulus BP
GO:0009725 response to hormone BP
GO:0009737 response to abscisic acid BP
GO:0009987 cellular process BP
GO:0010033 response to organic substance BP
GO:0016567 protein ubiquitination BP
GO:0016740 transferase activity MF
GO:0019538 protein metabolic process BP
GO:0019787 ubiquitin-like protein transferase activity MF
GO:0032446 protein modification by small protein conjugation BP
GO:0033993 response to lipid BP
GO:0036211 protein modification process BP
GO:0042221 response to chemical BP
GO:0043170 macromolecule metabolic process BP
GO:0043412 macromolecule modification BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0050896 response to stimulus BP
GO:0051087 chaperone binding MF
GO:0070647 protein modification by small protein conjugation or removal BP
GO:0071704 organic substance metabolic process BP
GO:0097305 response to alcohol BP
GO:0140096 catalytic activity, acting on a protein MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901700 response to oxygen-containing compound BP
KEGG Term Name Description
map04141 Protein processing in endoplasmic reticulum The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
map04120 Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.