Basic Information
Gene ID
Position
GWHASIS00000958:185534-196667 (-)
11133bp
Gene Type
gene
Gene Description (Protein Product)
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Organism
Also AS AT2G05710

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
EVM0034634 citrate synthase
EVM0031429 ATP-citrate synthase beta chain protein
EVM0030468 The B regulatory subunit might modulate substrate selectivity and catalytic activity; and also might direct the localization of the catalytic enzyme to a particular subcellular compartment
Regulatory gene
EVM0001315 transcription factor that promotes early floral meristem identity in synergy with APETALA1; FRUITFULL and LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Seems to be partially redundant to the function of APETALA1
EVM0003629 MADS-box protein
EVM0005245 MADS-box protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000166 nucleotide binding MF
GO:0001101 response to acid chemical BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0003994 aconitate hydratase activity MF
GO:0005488 binding MF
GO:0005507 copper ion binding MF
GO:0005524 ATP binding MF
GO:0005575 cellular_component CC
GO:0005618 cell wall CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0005773 vacuole CC
GO:0005774 vacuolar membrane CC
GO:0005829 cytosol CC
GO:0006082 organic acid metabolic process BP
GO:0006101 citrate metabolic process BP
GO:0006102 isocitrate metabolic process BP
GO:0006950 response to stress BP
GO:0006970 response to osmotic stress BP
GO:0006979 response to oxidative stress BP
GO:0007275 multicellular organism development BP
GO:0008144 obsolete drug binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009507 chloroplast CC
GO:0009532 plastid stroma CC
GO:0009536 plastid CC
GO:0009570 chloroplast stroma CC
GO:0009605 response to external stimulus BP
GO:0009628 response to abiotic stimulus BP
GO:0009651 response to salt stress BP
GO:0009719 response to endogenous stimulus BP
GO:0009725 response to hormone BP
GO:0009737 response to abscisic acid BP
GO:0009791 post-embryonic development BP
GO:0009987 cellular process BP
GO:0009991 response to extracellular stimulus BP
GO:0010033 response to organic substance BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0016020 membrane CC
GO:0016829 lyase activity MF
GO:0016835 carbon-oxygen lyase activity MF
GO:0016836 hydro-lyase activity MF
GO:0016999 antibiotic metabolic process BP
GO:0017076 purine nucleotide binding MF
GO:0017144 xenobiotic metabolic process BP
GO:0019752 carboxylic acid metabolic process BP
GO:0030312 external encapsulating structure CC
GO:0030554 adenyl nucleotide binding MF
GO:0031090 organelle membrane CC
GO:0031667 response to nutrient levels BP
GO:0032501 multicellular organismal process BP
GO:0032502 developmental process BP
GO:0032553 ribonucleotide binding MF
GO:0032555 purine ribonucleotide binding MF
GO:0032559 adenyl ribonucleotide binding MF
GO:0033993 response to lipid BP
GO:0035639 purine ribonucleoside triphosphate binding MF
GO:0036094 small molecule binding MF
GO:0042221 response to chemical BP
GO:0042594 response to starvation BP
GO:0043167 ion binding MF
GO:0043168 anion binding MF
GO:0043169 cation binding MF
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043436 oxoacid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044281 small molecule metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044434 obsolete chloroplast part CC
GO:0044435 obsolete plastid part CC
GO:0044437 obsolete vacuolar part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046686 response to cadmium ion BP
GO:0046872 metal ion binding MF
GO:0046914 transition metal ion binding MF
GO:0048856 anatomical structure development BP
GO:0050896 response to stimulus BP
GO:0071704 organic substance metabolic process BP
GO:0071944 cell periphery CC
GO:0072350 tricarboxylic acid metabolic process BP
GO:0090351 seedling development BP
GO:0097159 organic cyclic compound binding MF
GO:0097305 response to alcohol BP
GO:0097367 carbohydrate derivative binding MF
GO:0098588 bounding membrane of organelle CC
GO:0098805 membrane CC
GO:1901265 nucleoside phosphate binding MF
GO:1901363 heterocyclic compound binding MF
GO:1901700 response to oxygen-containing compound BP
GO:1990641 response to iron ion starvation BP
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00630 Glyoxylate and dicarboxylate metabolism -
map00020 Citrate cycle (TCA cycle) The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011].