Basic Information
Gene ID
Position
GWHASIS00001978:18906829-18913408 (+)
6579bp
Gene Type
gene
Gene Description (Protein Product)
Cystathionine beta-lyase
Organism
Also AS AT3G57050

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
EVM0035267 Belongs to the cysteine synthase cystathionine beta- synthase family
EVM0033312 1-aminocyclopropane-1-carboxylate deaminase
EVM0033980 Cystathionine gamma-synthase

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000096 sulfur amino acid metabolic process BP
GO:0000097 sulfur amino acid biosynthetic process BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0003962 cystathionine gamma-synthase activity MF
GO:0004121 cystathionine beta-lyase activity MF
GO:0004123 cystathionine gamma-lyase activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0006082 organic acid metabolic process BP
GO:0006520 amino acid metabolic process BP
GO:0006534 cysteine metabolic process BP
GO:0006555 methionine metabolic process BP
GO:0006790 sulfur compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008144 obsolete drug binding MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008652 amino acid biosynthetic process BP
GO:0009058 biosynthetic process BP
GO:0009066 aspartate family amino acid metabolic process BP
GO:0009067 aspartate family amino acid biosynthetic process BP
GO:0009069 serine family amino acid metabolic process BP
GO:0009070 serine family amino acid biosynthetic process BP
GO:0009086 methionine biosynthetic process BP
GO:0009092 homoserine metabolic process BP
GO:0009507 chloroplast CC
GO:0009532 plastid stroma CC
GO:0009536 plastid CC
GO:0009570 chloroplast stroma CC
GO:0009987 cellular process BP
GO:0016053 organic acid biosynthetic process BP
GO:0016740 transferase activity MF
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups MF
GO:0016829 lyase activity MF
GO:0016846 carbon-sulfur lyase activity MF
GO:0017144 xenobiotic metabolic process BP
GO:0019279 L-methionine biosynthetic process from L-homoserine via cystathionine BP
GO:0019343 cysteine biosynthetic process via cystathionine BP
GO:0019344 cysteine biosynthetic process BP
GO:0019346 transsulfuration BP
GO:0019752 carboxylic acid metabolic process BP
GO:0019842 vitamin binding MF
GO:0030170 pyridoxal phosphate binding MF
GO:0036094 small molecule binding MF
GO:0043167 ion binding MF
GO:0043168 anion binding MF
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043436 oxoacid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044272 sulfur compound biosynthetic process BP
GO:0044281 small molecule metabolic process BP
GO:0044283 small molecule biosynthetic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044434 obsolete chloroplast part CC
GO:0044435 obsolete plastid part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0046394 carboxylic acid biosynthetic process BP
GO:0048037 obsolete cofactor binding MF
GO:0050662 obsolete coenzyme binding MF
GO:0050667 homocysteine metabolic process BP
GO:0070279 vitamin B6 binding MF
GO:0071265 L-methionine biosynthetic process BP
GO:0071266 'de novo' L-methionine biosynthetic process BP
GO:0071704 organic substance metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:1901363 heterocyclic compound binding MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901566 organonitrogen compound biosynthetic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1901605 alpha-amino acid metabolic process BP
GO:1901607 alpha-amino acid biosynthetic process BP
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00450 Selenocompound metabolism -
map00270 Cysteine and methionine metabolism Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].