Basic Information
Gene ID
Position
GWHASIS00001973:54642884-54647356 (-)
4472bp
Gene Type
gene
Gene Description (Protein Product)
Permuted single zf-CXXC unit
Organism
Also AS AT2G36490

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
EVM0035207 Replication protein A 32 kDa subunit
EVM0034537 Belongs to the helicase family. Dicer subfamily
EVM0033944 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication; cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base; leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway; by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA; and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009987 cellular process BP
GO:0010216 negative regulation of gene expression via chromosomal DNA cytosine methylation BP
GO:0016787 hydrolase activity MF
GO:0016798 hydrolase activity, acting on glycosyl bonds MF
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds MF
GO:0019104 DNA N-glycosylase activity MF
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0071704 organic substance metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP