PPGR - Gene Detail

Basic Information

Gene ID	gene-Apse010G0026900 View in Genome Browser
Position	GWHBECT00000010:2459703-2462088 (-) 2385bp
Gene Type	gene
Gene Description (Protein Product)	Belongs to the adaptor complexes small subunit family
Organism	Acer pseudosieboldianum
Also AS	AT1G47830

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Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

gene-Apse011G0048400 Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi trans-Golgi network (TGN) and or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules

gene-Apse012G0187800 Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

gene-Apse013G0052000 Clathrin is the major protein of the polyhedral coat of coated pits and vesicles

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0005575	cellular_component	CC
GO:0005623	obsolete cell	CC
GO:0005886	plasma membrane	CC
GO:0005905	clathrin-coated pit	CC
GO:0012505	endomembrane system	CC
GO:0016020	membrane	CC
GO:0044425	obsolete membrane part	CC
GO:0044464	obsolete cell part	CC
GO:0071944	cell periphery	CC

KEGG Term	Name	Description
map04144	Endocytosis	Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type.