Basic Information
Gene ID
Atru.chr5.1036.g
Position
chr5:10037624-10044459 (-)
6835bp
Gene Type
gene
Gene Description (Protein Product)
BRCT domain-containing protein
Organism
Also AS AT4G02110

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Atru.chr6.1420.g Cell division control protein 45 homolog
Atru.chr9.2479.g serine threonine-protein kinase
Atru.chr5.1799.g Protein BREAST CANCER SUSCEPTIBILITY
Regulatory gene
Atru.chr1.1136.g Agamous-like MADS-box protein
Atru.chr1.3656.g dof zinc finger protein
Atru.chr1.556.g MADS-box protein SOC1-like

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.