Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0005096 | GTPase activator activity | MF |
| GO:0005488 | binding | MF |
| GO:0005543 | phospholipid binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005773 | vacuole | CC |
| GO:0005794 | Golgi apparatus | CC |
| GO:0005886 | plasma membrane | CC |
| GO:0006810 | transport | BP |
| GO:0006886 | intracellular protein transport | BP |
| GO:0007275 | multicellular organism development | BP |
| GO:0008047 | enzyme activator activity | MF |
| GO:0008104 | protein localization | BP |
| GO:0008150 | biological_process | BP |
| GO:0008289 | lipid binding | MF |
| GO:0009555 | pollen development | BP |
| GO:0012505 | endomembrane system | CC |
| GO:0015031 | protein transport | BP |
| GO:0015833 | peptide transport | BP |
| GO:0016020 | membrane | CC |
| GO:0030234 | enzyme regulator activity | MF |
| GO:0030695 | GTPase regulator activity | MF |
| GO:0032501 | multicellular organismal process | BP |
| GO:0032502 | developmental process | BP |
| GO:0033036 | macromolecule localization | BP |
| GO:0034613 | protein localization | BP |
| GO:0042886 | amide transport | BP |
| GO:0043085 | positive regulation of catalytic activity | BP |
| GO:0043087 | regulation of GTPase activity | BP |
| GO:0043167 | ion binding | MF |
| GO:0043168 | anion binding | MF |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043547 | positive regulation of GTPase activity | BP |
| GO:0044093 | positive regulation of molecular function | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0045184 | establishment of protein localization | BP |
| GO:0046907 | intracellular transport | BP |
| GO:0048229 | gametophyte development | BP |
| GO:0048856 | anatomical structure development | BP |
| GO:0050790 | regulation of catalytic activity | BP |
| GO:0051179 | localization | BP |
| GO:0051234 | establishment of localization | BP |
| GO:0051336 | regulation of hydrolase activity | BP |
| GO:0051345 | positive regulation of hydrolase activity | BP |
| GO:0051641 | cellular localization | BP |
| GO:0051649 | establishment of localization in cell | BP |
| GO:0060589 | nucleoside-triphosphatase regulator activity | MF |
| GO:0065007 | biological regulation | BP |
| GO:0065009 | regulation of molecular function | BP |
| GO:0070727 | cellular macromolecule localization | BP |
| GO:0071702 | organic substance transport | BP |
| GO:0071705 | nitrogen compound transport | BP |
| GO:0071944 | cell periphery | CC |
| GO:0098772 | molecular function regulator activity | MF |
| KEGG Term | Name | Description |
|---|---|---|
| map04144 | Endocytosis | Endocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins entering through clathrin-dependent endocytosis (CDE) have sequences in their cytoplasmic domains that bind to the APs (adaptor-related protein complexes) and enable their rapid removal from the PM. In addition to APs and clathrin, there are numerous accessory proteins including dynamin. Depending on the various proteins that enter the endosome membrane, these cargoes are sorted to distinct destinations. Some cargoes, such as nutrient receptors, are recycled back to the PM. Ubiquitylated membrane proteins, such as activated growth-factor receptors, are sorted into intraluminal vesicles and eventually end up in the lysosome lumen via multivesicular endosomes (MVEs). There are distinct mechanisms of clathrin-independent endocytosis (CIE) depending upon the cargo and the cell type. |