PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Pathway

Basic Information

Gene ID	AmTr_scaff00029.278.v1.0.g View in Genome Browser
Position	AmTr_scaff00029:3682813-3684161 (-) 1348bp
Gene Type	gene
Gene Description (Protein Product)	ATP binding
Organism	Amborella trichopoda
Also AS	AT5G42020AMTR_s00029p00199940

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	AmTr_scaff00175.37.v1.0.g protein disulfide isomerase-like AmTr_scaff00099.155.v1.0.g E3 ubiquitin-protein ligase AmTr_scaff00186.14.v1.0.g disulfide-isomerase
Regulatory gene	AmTr_scaff00001.1.v1.0.g transcription, DNA-templated AmTr_scaff00001.321.v1.0.g Trihelix transcription factor AmTr_scaff00001.416.v1.0.g -

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0000082	G1/S transition of mitotic cell cycle	BP
GO:0000166	nucleotide binding	MF
GO:0000278	mitotic cell cycle	BP
GO:0000323	lytic vacuole	CC
GO:0000902	cell morphogenesis	BP
GO:0000904	cell morphogenesis involved in differentiation	BP
GO:0000974	Prp19 complex	CC
GO:0001655	urogenital system development	BP
GO:0001664	G protein-coupled receptor binding	MF
GO:0001822	kidney development	BP
GO:0001910	regulation of leukocyte mediated cytotoxicity	BP
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	BP
GO:0001914	regulation of T cell mediated cytotoxicity	BP
GO:0001916	positive regulation of T cell mediated cytotoxicity	BP
GO:0001917	photoreceptor inner segment	CC
GO:0002682	regulation of immune system process	BP
GO:0002684	positive regulation of immune system process	BP
GO:0002697	regulation of immune effector process	BP
GO:0002699	positive regulation of immune effector process	BP
GO:0002703	regulation of leukocyte mediated immunity	BP
GO:0002705	positive regulation of leukocyte mediated immunity	BP
GO:0002706	regulation of lymphocyte mediated immunity	BP
GO:0002708	positive regulation of lymphocyte mediated immunity	BP
GO:0002709	regulation of T cell mediated immunity	BP
GO:0002711	positive regulation of T cell mediated immunity	BP
GO:0002819	regulation of adaptive immune response	BP
GO:0002821	positive regulation of adaptive immune response	BP
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	BP
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	BP
GO:0003006	developmental process involved in reproduction	BP
GO:0003008	system process	BP
GO:0003674	molecular_function	MF
GO:0003676	nucleic acid binding	MF
GO:0003723	RNA binding	MF
GO:0003824	catalytic activity	MF
GO:0005102	signaling receptor binding	MF
GO:0005488	binding	MF
GO:0005504	fatty acid binding	MF
GO:0005515	protein binding	MF
GO:0005524	ATP binding	MF
GO:0005575	cellular_component	CC
GO:0005576	extracellular region	CC
GO:0005615	extracellular space	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005737	cytoplasm	CC
GO:0005764	lysosome	CC
GO:0005765	lysosomal membrane	CC
GO:0005773	vacuole	CC
GO:0005774	vacuolar membrane	CC
GO:0005775	vacuolar lumen	CC
GO:0005776	autophagosome	CC
GO:0005783	endoplasmic reticulum	CC
GO:0005788	endoplasmic reticulum lumen	CC
GO:0005829	cytosol	CC
GO:0005856	cytoskeleton	CC
GO:0005874	microtubule	CC
GO:0005882	intermediate filament	CC
GO:0006355	regulation of DNA-templated transcription	BP
GO:0006457	protein folding	BP
GO:0006464	protein modification process	BP
GO:0006468	protein phosphorylation	BP
GO:0006518	peptide metabolic process	BP
GO:0006606	protein import into nucleus	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006810	transport	BP
GO:0006886	intracellular protein transport	BP
GO:0006897	endocytosis	BP
GO:0006913	nucleocytoplasmic transport	BP
GO:0006914	autophagy	BP
GO:0006928	obsolete movement of cell or subcellular component	BP
GO:0006950	response to stress	BP
GO:0006996	organelle organization	BP
GO:0007017	microtubule-based process	BP
GO:0007018	microtubule-based movement	BP
GO:0007033	vacuole organization	BP
GO:0007040	lysosome organization	BP
GO:0007049	cell cycle	BP
GO:0007275	multicellular organism development	BP
GO:0007399	nervous system development	BP
GO:0007417	central nervous system development	BP
GO:0007420	brain development	BP
GO:0007517	muscle organ development	BP
GO:0007519	skeletal muscle tissue development	BP
GO:0007568	aging	BP
GO:0007600	sensory perception	BP
GO:0007606	sensory perception of chemical stimulus	BP
GO:0007608	sensory perception of smell	BP
GO:0008021	synaptic vesicle	CC
GO:0008088	axo-dendritic transport	BP
GO:0008104	protein localization	BP
GO:0008134	transcription factor binding	MF
GO:0008144	obsolete drug binding	MF
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008289	lipid binding	MF
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009266	response to temperature stimulus	BP
GO:0009408	response to heat	BP
GO:0009605	response to external stimulus	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009636	response to toxic substance	BP
GO:0009653	anatomical structure morphogenesis	BP
GO:0009719	response to endogenous stimulus	BP
GO:0009725	response to hormone	BP
GO:0009826	unidimensional cell growth	BP
GO:0009856	pollination	BP
GO:0009860	pollen tube growth	BP
GO:0009888	tissue development	BP
GO:0009889	regulation of biosynthetic process	BP
GO:0009890	negative regulation of biosynthetic process	BP
GO:0009892	negative regulation of metabolic process	BP
GO:0009893	positive regulation of metabolic process	BP
GO:0009932	cell tip growth	BP
GO:0009986	cell surface	CC
GO:0009987	cellular process	BP
GO:0009991	response to extracellular stimulus	BP
GO:0010033	response to organic substance	BP
GO:0010035	response to inorganic substance	BP
GO:0010038	response to metal ion	BP
GO:0010045	response to nickel cation	BP
GO:0010468	regulation of gene expression	BP
GO:0010556	regulation of macromolecule biosynthetic process	BP
GO:0010558	negative regulation of macromolecule biosynthetic process	BP
GO:0010604	positive regulation of macromolecule metabolic process	BP
GO:0010605	negative regulation of macromolecule metabolic process	BP
GO:0010628	positive regulation of gene expression	BP
GO:0010629	negative regulation of gene expression	BP
GO:0010656	negative regulation of muscle cell apoptotic process	BP
GO:0010660	regulation of muscle cell apoptotic process	BP
GO:0010662	regulation of striated muscle cell apoptotic process	BP
GO:0010664	negative regulation of striated muscle cell apoptotic process	BP
GO:0010665	regulation of cardiac muscle cell apoptotic process	BP
GO:0010667	negative regulation of cardiac muscle cell apoptotic process	BP
GO:0010941	regulation of cell death	BP
GO:0010970	transport along microtubule	BP
GO:0012505	endomembrane system	CC
GO:0014069	postsynaptic density	CC
GO:0014070	response to organic cyclic compound	BP
GO:0014706	striated muscle tissue development	BP
GO:0014823	response to activity	BP
GO:0015031	protein transport	BP
GO:0015630	microtubule cytoskeleton	CC
GO:0015833	peptide transport	BP
GO:0016020	membrane	CC
GO:0016043	cellular component organization	BP
GO:0016049	cell growth	BP
GO:0016191	synaptic vesicle uncoating	BP
GO:0016192	vesicle-mediated transport	BP
GO:0016310	phosphorylation	BP
GO:0016462	pyrophosphatase activity	MF
GO:0016592	mediator complex	CC
GO:0016787	hydrolase activity	MF
GO:0016817	hydrolase activity, acting on acid anhydrides	MF
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MF
GO:0016887	ATP hydrolysis activity	MF
GO:0017038	protein import	BP
GO:0017076	purine nucleotide binding	MF
GO:0017111	ribonucleoside triphosphate phosphatase activity	MF
GO:0019219	regulation of nucleobase-containing compound metabolic process	BP
GO:0019222	regulation of metabolic process	BP
GO:0019538	protein metabolic process	BP
GO:0019899	enzyme binding	MF
GO:0021549	cerebellum development	BP
GO:0022037	metencephalon development	BP
GO:0022402	cell cycle process	BP
GO:0022411	cellular component disassembly	BP
GO:0022414	reproductive process	BP
GO:0030100	regulation of endocytosis	BP
GO:0030133	transport vesicle	CC
GO:0030154	cell differentiation	BP
GO:0030162	regulation of proteolysis	BP
GO:0030163	protein catabolic process	BP
GO:0030424	axon	CC
GO:0030425	dendrite	CC
GO:0030554	adenyl nucleotide binding	MF
GO:0030705	cytoskeleton-dependent intracellular transport	BP
GO:0030900	forebrain development	BP
GO:0030902	hindbrain development	BP
GO:0031090	organelle membrane	CC
GO:0031323	regulation of cellular metabolic process	BP
GO:0031324	negative regulation of cellular metabolic process	BP
GO:0031325	positive regulation of cellular metabolic process	BP
GO:0031326	regulation of cellular biosynthetic process	BP
GO:0031327	negative regulation of cellular biosynthetic process	BP
GO:0031341	regulation of cell killing	BP
GO:0031343	positive regulation of cell killing	BP
GO:0031406	carboxylic acid binding	MF
GO:0031410	cytoplasmic vesicle	CC
GO:0031667	response to nutrient levels	BP
GO:0031685	adenosine receptor binding	MF
GO:0031686	A1 adenosine receptor binding	MF
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0031982	vesicle	CC
GO:0032268	regulation of protein metabolic process	BP
GO:0032270	positive regulation of protein metabolic process	BP
GO:0032279	asymmetric synapse	CC
GO:0032355	response to estradiol	BP
GO:0032501	multicellular organismal process	BP
GO:0032502	developmental process	BP
GO:0032504	multicellular organism reproduction	BP
GO:0032553	ribonucleotide binding	MF
GO:0032555	purine ribonucleotide binding	MF
GO:0032559	adenyl ribonucleotide binding	MF
GO:0032570	response to progesterone	BP
GO:0032879	regulation of localization	BP
GO:0032984	protein-containing complex disassembly	BP
GO:0032989	cellular component morphogenesis	BP
GO:0032991	protein-containing complex	CC
GO:0033036	macromolecule localization	BP
GO:0033218	amide binding	MF
GO:0033267	obsolete axon part	CC
GO:0033293	monocarboxylic acid binding	MF
GO:0033365	protein localization to organelle	BP
GO:0033554	cellular response to stress	BP
GO:0033993	response to lipid	BP
GO:0034504	protein localization to nucleus	BP
GO:0034605	cellular response to heat	BP
GO:0034613	protein localization	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0035639	purine ribonucleoside triphosphate binding	MF
GO:0036094	small molecule binding	MF
GO:0036211	protein modification process	BP
GO:0036465	synaptic vesicle recycling	BP
GO:0036477	somatodendritic compartment	CC
GO:0040007	growth	BP
GO:0042026	protein refolding	BP
GO:0042221	response to chemical	BP
GO:0042277	peptide binding	MF
GO:0042493	response to xenobiotic stimulus	BP
GO:0042594	response to starvation	BP
GO:0042623	ATP hydrolysis activity	MF
GO:0042698	ovulation cycle	BP
GO:0042886	amide transport	BP
GO:0042981	regulation of apoptotic process	BP
GO:0042995	cell projection	CC
GO:0043005	neuron projection	CC
GO:0043025	neuronal cell body	CC
GO:0043066	negative regulation of apoptotic process	BP
GO:0043067	regulation of programmed cell death	BP
GO:0043069	negative regulation of programmed cell death	BP
GO:0043085	positive regulation of catalytic activity	BP
GO:0043167	ion binding	MF
GO:0043168	anion binding	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043177	organic acid binding	MF
GO:0043195	terminal bouton	CC
GO:0043197	dendritic spine	CC
GO:0043198	dendritic shaft	CC
GO:0043202	lysosomal lumen	CC
GO:0043204	perikaryon	CC
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043230	extracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043412	macromolecule modification	BP
GO:0043531	ADP binding	MF
GO:0043603	amide metabolic process	BP
GO:0043624	protein-containing complex disassembly	BP
GO:0043679	axon terminus	CC
GO:0043933	protein-containing complex organization	BP
GO:0044093	positive regulation of molecular function	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044297	cell body	CC
GO:0044306	neuron projection terminus	CC
GO:0044309	neuron spine	CC
GO:0044421	obsolete extracellular region part	CC
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044425	obsolete membrane part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044430	obsolete cytoskeletal part	CC
GO:0044432	obsolete endoplasmic reticulum part	CC
GO:0044437	obsolete vacuolar part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044445	obsolete cytosolic part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044451	obsolete nucleoplasm part	CC
GO:0044456	obsolete synapse part	CC
GO:0044463	obsolete cell projection part	CC
GO:0044464	obsolete cell part	CC
GO:0044706	multi-multicellular organism process	BP
GO:0044743	protein transmembrane import into intracellular organelle	BP
GO:0044770	cell cycle phase transition	BP
GO:0044772	mitotic cell cycle phase transition	BP
GO:0044843	cell cycle G1/S phase transition	BP
GO:0044849	estrous cycle	BP
GO:0045111	intermediate filament cytoskeleton	CC
GO:0045121	membrane raft	CC
GO:0045184	establishment of protein localization	BP
GO:0045202	synapse	CC
GO:0045471	response to ethanol	BP
GO:0045807	positive regulation of endocytosis	BP
GO:0045862	positive regulation of proteolysis	BP
GO:0045892	negative regulation of DNA-templated transcription	BP
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	BP
GO:0046677	response to antibiotic	BP
GO:0046686	response to cadmium ion	BP
GO:0046777	protein autophosphorylation	BP
GO:0046907	intracellular transport	BP
GO:0048468	cell development	BP
GO:0048471	perinuclear region of cytoplasm	CC
GO:0048488	synaptic vesicle endocytosis	BP
GO:0048511	rhythmic process	BP
GO:0048513	animal organ development	BP
GO:0048518	positive regulation of biological process	BP
GO:0048519	negative regulation of biological process	BP
GO:0048522	positive regulation of cellular process	BP
GO:0048523	negative regulation of cellular process	BP
GO:0048545	response to steroid hormone	BP
GO:0048583	regulation of response to stimulus	BP
GO:0048584	positive regulation of response to stimulus	BP
GO:0048585	negative regulation of response to stimulus	BP
GO:0048588	developmental cell growth	BP
GO:0048589	developmental growth	BP
GO:0048609	multicellular organismal reproductive process	BP
GO:0048731	system development	BP
GO:0048856	anatomical structure development	BP
GO:0048868	pollen tube development	BP
GO:0048869	cellular developmental process	BP
GO:0050542	icosanoid binding	MF
GO:0050764	regulation of phagocytosis	BP
GO:0050766	positive regulation of phagocytosis	BP
GO:0050776	regulation of immune response	BP
GO:0050778	positive regulation of immune response	BP
GO:0050789	regulation of biological process	BP
GO:0050790	regulation of catalytic activity	BP
GO:0050794	regulation of cellular process	BP
GO:0050877	nervous system process	BP
GO:0050896	response to stimulus	BP
GO:0051049	regulation of transport	BP
GO:0051050	positive regulation of transport	BP
GO:0051082	unfolded protein binding	MF
GO:0051128	regulation of cellular component organization	BP
GO:0051130	positive regulation of cellular component organization	BP
GO:0051169	nuclear transport	BP
GO:0051170	import into nucleus	BP
GO:0051171	regulation of nitrogen compound metabolic process	BP
GO:0051172	negative regulation of nitrogen compound metabolic process	BP
GO:0051173	positive regulation of nitrogen compound metabolic process	BP
GO:0051179	localization	BP
GO:0051234	establishment of localization	BP
GO:0051246	regulation of protein metabolic process	BP
GO:0051247	positive regulation of protein metabolic process	BP
GO:0051252	regulation of RNA metabolic process	BP
GO:0051253	negative regulation of RNA metabolic process	BP
GO:0051261	protein depolymerization	BP
GO:0051641	cellular localization	BP
GO:0051649	establishment of localization in cell	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051716	cellular response to stimulus	BP
GO:0055085	transmembrane transport	BP
GO:0060255	regulation of macromolecule metabolic process	BP
GO:0060322	head development	BP
GO:0060537	muscle tissue development	BP
GO:0060538	skeletal muscle organ development	BP
GO:0060548	negative regulation of cell death	BP
GO:0060560	developmental growth involved in morphogenesis	BP
GO:0060627	regulation of vesicle-mediated transport	BP
GO:0061024	membrane organization	BP
GO:0061061	muscle structure development	BP
GO:0061077	chaperone-mediated protein folding	BP
GO:0061083	regulation of protein refolding	BP
GO:0061635	regulation of protein complex stability	BP
GO:0061684	chaperone-mediated autophagy	BP
GO:0061741	obsolete chaperone-mediated protein transport involved in chaperone-mediated autophagy	BP
GO:0061919	process utilizing autophagic mechanism	BP
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0065009	regulation of molecular function	BP
GO:0070013	intracellular organelle lumen	CC
GO:0070062	extracellular exosome	CC
GO:0070382	exocytic vesicle	CC
GO:0070727	cellular macromolecule localization	BP
GO:0070887	cellular response to chemical stimulus	BP
GO:0071241	cellular response to inorganic substance	BP
GO:0071248	cellular response to metal ion	BP
GO:0071276	cellular response to cadmium ion	BP
GO:0071702	organic substance transport	BP
GO:0071704	organic substance metabolic process	BP
GO:0071705	nitrogen compound transport	BP
GO:0071806	protein transmembrane transport	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0072001	renal system development	BP
GO:0072318	clathrin coat disassembly	BP
GO:0072319	vesicle uncoating	BP
GO:0072321	obsolete chaperone-mediated protein transport	BP
GO:0072594	establishment of protein localization to organelle	BP
GO:0080090	regulation of primary metabolic process	BP
GO:0080134	regulation of response to stress	BP
GO:0080135	regulation of cellular response to stress	BP
GO:0080171	lytic vacuole organization	BP
GO:0090559	regulation of membrane permeability	BP
GO:0097159	organic cyclic compound binding	MF
GO:0097212	lysosomal membrane organization	BP
GO:0097213	regulation of lysosomal membrane permeability	BP
GO:0097214	positive regulation of lysosomal membrane permeability	BP
GO:0097305	response to alcohol	BP
GO:0097367	carbohydrate derivative binding	MF
GO:0097447	dendritic tree	CC
GO:0097458	obsolete neuron part	CC
GO:0097708	intracellular vesicle	CC
GO:0098588	bounding membrane of organelle	CC
GO:0098589	membrane	CC
GO:0098657	import into cell	BP
GO:0098793	presynapse	CC
GO:0098794	postsynapse	CC
GO:0098805	membrane	CC
GO:0098852	lytic vacuole membrane	CC
GO:0098857	membrane microdomain	CC
GO:0098984	neuron to neuron synapse	CC
GO:0099003	vesicle-mediated transport in synapse	BP
GO:0099080	supramolecular complex	CC
GO:0099081	supramolecular polymer	CC
GO:0099111	microtubule-based transport	BP
GO:0099503	secretory vesicle	CC
GO:0099504	synaptic vesicle cycle	BP
GO:0099512	supramolecular fiber	CC
GO:0099513	polymeric cytoskeletal fiber	CC
GO:0099522	cytosolic region	CC
GO:0099523	presynaptic cytosol	CC
GO:0099524	postsynaptic cytosol	CC
GO:0099572	postsynaptic specialization	CC
GO:0120025	plasma membrane bounded cell projection	CC
GO:0120038	obsolete plasma membrane bounded cell projection part	CC
GO:0150034	distal axon	CC
GO:1900407	regulation of cellular response to oxidative stress	BP
GO:1900408	negative regulation of cellular response to oxidative stress	BP
GO:1901031	regulation of response to reactive oxygen species	BP
GO:1901032	negative regulation of response to reactive oxygen species	BP
GO:1901265	nucleoside phosphate binding	MF
GO:1901363	heterocyclic compound binding	MF
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901567	fatty acid derivative binding	MF
GO:1901575	organic substance catabolic process	BP
GO:1901654	response to ketone	BP
GO:1901700	response to oxygen-containing compound	BP
GO:1902679	negative regulation of RNA biosynthetic process	BP
GO:1902882	regulation of response to oxidative stress	BP
GO:1902883	negative regulation of response to oxidative stress	BP
GO:1903047	mitotic cell cycle process	BP
GO:1903201	regulation of oxidative stress-induced cell death	BP
GO:1903202	negative regulation of oxidative stress-induced cell death	BP
GO:1903205	regulation of hydrogen peroxide-induced cell death	BP
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	BP
GO:1903332	regulation of protein folding	BP
GO:1903334	positive regulation of protein folding	BP
GO:1903506	regulation of nucleic acid-templated transcription	BP
GO:1903507	negative regulation of nucleic acid-templated transcription	BP
GO:1903561	extracellular vesicle	CC
GO:1904592	positive regulation of protein refolding	BP
GO:1904593	prostaglandin binding	MF
GO:1904764	chaperone-mediated autophagy translocation complex disassembly	BP
GO:1905710	positive regulation of membrane permeability	BP
GO:1990124	messenger ribonucleoprotein complex	CC
GO:1990832	slow axonal transport	BP
GO:1990833	clathrin-uncoating ATPase activity	MF
GO:1990834	response to odorant	BP
GO:1990836	lysosomal matrix	CC
GO:1990904	ribonucleoprotein complex	CC
GO:2000112	regulation of cellular macromolecule biosynthetic process	BP
GO:2000113	negative regulation of cellular macromolecule biosynthetic process	BP
GO:2001023	regulation of response to drug	BP
GO:2001024	negative regulation of response to drug	BP
GO:2001038	regulation of cellular response to drug	BP
GO:2001039	negative regulation of cellular response to drug	BP
GO:2001141	regulation of RNA biosynthetic process	BP

KEGG Term	Name	Description
map04141	Protein processing in endoplasmic reticulum	The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
map03060	Protein export	The protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the general protein export system that transports newly synthesized proteins into or across the cell membrane. The translocation channel is formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex. The twin-arginine translocation (Tat) pathway is another protein transport system that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems comprise three functionally different membrane proteins, TatA, TatB, and TatC, but TatA and TatE seem to have overlapping functions, with TatA having by far the more important role.