Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
AmTr_scaff00126.55.v1.0.g
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Position
AmTr_scaff00126:1505006-1565173 (-)
60167bp
Gene Type
gene
Gene Description (Protein Product)
DNA repair and recombination protein
Organism
Amborella trichopoda
Also AS AT3G19210AMTR_s00126p00116180

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
AmTr_scaff00129.59.v1.0.g Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination
AmTr_scaff00142.46.v1.0.g SNF2 domain-containing protein CLASSY
AmTr_scaff00228.2.v1.0.g Small ubiquitin-related modifier

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000018 regulation of DNA recombination BP
GO:0000280 nuclear division BP
GO:0000724 double-strand break repair via homologous recombination BP
GO:0000725 recombinational repair BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003824 catalytic activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005694 chromosome CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006302 double-strand break repair BP
GO:0006310 DNA recombination BP
GO:0006311 meiotic gene conversion BP
GO:0006325 chromatin organization BP
GO:0006338 chromatin remodeling BP
GO:0006342 heterochromatin formation BP
GO:0006355 regulation of DNA-templated transcription BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006996 organelle organization BP
GO:0007049 cell cycle BP
GO:0007127 meiosis I BP
GO:0007131 reciprocal meiotic recombination BP
GO:0008094 ATP-dependent activity, acting on DNA MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009314 response to radiation BP
GO:0009628 response to abiotic stimulus BP
GO:0009889 regulation of biosynthetic process BP
GO:0009890 negative regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0010212 response to ionizing radiation BP
GO:0010332 response to gamma radiation BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010558 negative regulation of macromolecule biosynthetic process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010629 negative regulation of gene expression BP
GO:0015616 DNA translocase activity MF
GO:0016043 cellular component organization BP
GO:0016458 obsolete gene silencing BP
GO:0016462 pyrophosphatase activity MF
GO:0016787 hydrolase activity MF
GO:0016817 hydrolase activity, acting on acid anhydrides MF
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides MF
GO:0016887 ATP hydrolysis activity MF
GO:0017111 ribonucleoside triphosphate phosphatase activity MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0030491 heteroduplex formation BP
GO:0030702 pericentric heterochromatin formation BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031327 negative regulation of cellular biosynthetic process BP
GO:0033170 DNA clamp loader activity MF
GO:0033554 cellular response to stress BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0035822 gene conversion BP
GO:0035825 homologous recombination BP
GO:0035861 site of double-strand break CC
GO:0040029 epigenetic regulation of gene expression BP
GO:0042221 response to chemical BP
GO:0042623 ATP hydrolysis activity MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044403 biological process involved in symbiotic interaction BP
GO:0044419 biological process involved in interspecies interaction between organisms BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044427 obsolete chromosomal part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0045003 double-strand break repair via synthesis-dependent strand annealing BP
GO:0045814 negative regulation of gene expression, epigenetic BP
GO:0045892 negative regulation of DNA-templated transcription BP
GO:0045934 negative regulation of nucleobase-containing compound metabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0048285 organelle fission BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051052 regulation of DNA metabolic process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051253 negative regulation of RNA metabolic process BP
GO:0051276 chromosome organization BP
GO:0051321 meiotic cell cycle BP
GO:0051701 biological process involved in interaction with host BP
GO:0051704 obsolete multi-organism process BP
GO:0051716 cellular response to stimulus BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0061806 regulation of DNA recombination at centromere BP
GO:0061982 meiosis I cell cycle process BP
GO:0065007 biological regulation BP
GO:0070887 cellular response to chemical stimulus BP
GO:0071214 cellular response to abiotic stimulus BP
GO:0071241 cellular response to inorganic substance BP
GO:0071248 cellular response to metal ion BP
GO:0071478 cellular response to radiation BP
GO:0071479 cellular response to ionizing radiation BP
GO:0071480 cellular response to gamma radiation BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0080090 regulation of primary metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090734 site of DNA damage CC
GO:0097159 organic cyclic compound binding MF
GO:0104004 cellular response to environmental stimulus BP
GO:0140013 meiotic nuclear division BP
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1902679 negative regulation of RNA biosynthetic process BP
GO:1903046 meiotic cell cycle process BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:1903507 negative regulation of nucleic acid-templated transcription BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000113 negative regulation of cellular macromolecule biosynthetic process BP
GO:2001141 regulation of RNA biosynthetic process BP
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.