Basic Information
Gene ID
Bpev01.c5392.g0002
Position
Contig5392:1005-1841 (+)
836bp
Gene Type
gene
Gene Description (Protein Product)
"The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules
Organism
Also AS

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Bpev01.c5585.g0002 Catalyzes the hydrolytic deamination of cytosine to uracil. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis. Is also able to catalyze deamination of isoguanine, a mutagenic oxidation product of adenine in DNA, and of isocytosine. To a lesser extent, also catalyzes the conversion of 5- fluorocytosine (5FC) to 5-fluorouracil (5FU)
Bpev01.c5625.g0002 Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site
Bpev01.c5567.g0001 Phage-related protein, tail component

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004731 purine-nucleoside phosphorylase activity MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006148 inosine catabolic process BP
GO:0006149 deoxyinosine catabolic process BP
GO:0006152 purine nucleoside catabolic process BP
GO:0006161 deoxyguanosine catabolic process BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008477 purine nucleosidase activity MF
GO:0008617 guanosine metabolic process BP
GO:0009056 catabolic process BP
GO:0009116 nucleoside metabolic process BP
GO:0009119 ribonucleoside metabolic process BP
GO:0009120 deoxyribonucleoside metabolic process BP
GO:0009164 nucleoside catabolic process BP
GO:0009987 cellular process BP
GO:0015949 nucleobase-containing small molecule interconversion BP
GO:0016043 cellular component organization BP
GO:0016740 transferase activity MF
GO:0016757 glycosyltransferase activity MF
GO:0016763 pentosyltransferase activity MF
GO:0016787 hydrolase activity MF
GO:0016798 hydrolase activity, acting on glycosyl bonds MF
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds MF
GO:0019439 aromatic compound catabolic process BP
GO:0022607 cellular component assembly BP
GO:0034214 protein hexamerization BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034655 nucleobase-containing compound catabolic process BP
GO:0034656 nucleobase-containing small molecule catabolic process BP
GO:0042278 purine nucleoside metabolic process BP
GO:0042453 deoxyguanosine metabolic process BP
GO:0042454 ribonucleoside catabolic process BP
GO:0042802 identical protein binding MF
GO:0043933 protein-containing complex organization BP
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044270 cellular nitrogen compound catabolic process BP
GO:0044281 small molecule metabolic process BP
GO:0044282 small molecule catabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0046094 deoxyinosine metabolic process BP
GO:0046102 inosine metabolic process BP
GO:0046115 guanosine catabolic process BP
GO:0046121 deoxyribonucleoside catabolic process BP
GO:0046122 purine deoxyribonucleoside metabolic process BP
GO:0046124 purine deoxyribonucleoside catabolic process BP
GO:0046128 purine ribonucleoside metabolic process BP
GO:0046130 purine ribonucleoside catabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0046700 heterocycle catabolic process BP
GO:0047724 inosine nucleosidase activity MF
GO:0047975 guanosine phosphorylase activity MF
GO:0051259 protein complex oligomerization BP
GO:0055086 nucleobase-containing small molecule metabolic process BP
GO:0065003 protein-containing complex assembly BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0072521 purine-containing compound metabolic process BP
GO:0072523 purine-containing compound catabolic process BP
GO:1901068 guanosine-containing compound metabolic process BP
GO:1901069 guanosine-containing compound catabolic process BP
GO:1901135 carbohydrate derivative metabolic process BP
GO:1901136 carbohydrate derivative catabolic process BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1901361 organic cyclic compound catabolic process BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901657 glycosyl compound metabolic process BP
GO:1901658 glycosyl compound catabolic process BP
GO:1903227 xanthosine metabolic process BP
GO:1903228 xanthosine catabolic process BP
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map01100 Metabolic pathways -
map01100 Metabolic pathways -
map00760 Nicotinate and nicotinamide metabolism -
map00270 Cysteine and methionine metabolism Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
map00270 Cysteine and methionine metabolism Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
map00230 Purine metabolism -