Basic Information
Gene ID
Position
Chr2:41522340-41526239 (+)
3899bp
Gene Type
gene
Gene Description (Protein Product)
"Component of the anaphase promoting complex cyclosome (APC C)
Organism
Also AS AT2G18290

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
CSS0025697.g Cell division cycle 20.2, cofactor of APC complex-like
CSS0025119.g Cell division cycle 20.2, cofactor of APC complex-like
CSS0031752.g Cell division cycle 20.2, cofactor of APC complex-like
Regulatory gene
CSS0000305.g Zinc finger protein
CSS0001087.g ZINC FINGER protein
CSS0002339.g zinc finger

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000151 ubiquitin ligase complex CC
GO:0000152 nuclear ubiquitin ligase complex CC
GO:0000209 protein polyubiquitination BP
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005680 anaphase-promoting complex CC
GO:0006275 regulation of DNA replication BP
GO:0006464 protein modification process BP
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008156 negative regulation of DNA replication BP
GO:0008283 cell population proliferation BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009888 tissue development BP
GO:0009889 regulation of biosynthetic process BP
GO:0009890 negative regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009893 positive regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010087 phloem or xylem histogenesis BP
GO:0010498 proteasomal protein catabolic process BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010558 negative regulation of macromolecule biosynthetic process BP
GO:0010564 regulation of cell cycle process BP
GO:0010604 positive regulation of macromolecule metabolic process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010948 negative regulation of cell cycle process BP
GO:0016567 protein ubiquitination BP
GO:0016604 nuclear body CC
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0019941 modification-dependent protein catabolic process BP
GO:0030163 protein catabolic process BP
GO:0031145 anaphase-promoting complex-dependent catabolic process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031325 positive regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031327 negative regulation of cellular biosynthetic process BP
GO:0031396 regulation of protein ubiquitination BP
GO:0031398 positive regulation of protein ubiquitination BP
GO:0031399 regulation of protein modification process BP
GO:0031401 positive regulation of protein modification process BP
GO:0031461 cullin-RING ubiquitin ligase complex CC
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032268 regulation of protein metabolic process BP
GO:0032270 positive regulation of protein metabolic process BP
GO:0032446 protein modification by small protein conjugation BP
GO:0032502 developmental process BP
GO:0032875 regulation of DNA endoreduplication BP
GO:0032876 negative regulation of DNA endoreduplication BP
GO:0032991 protein-containing complex CC
GO:0036211 protein modification process BP
GO:0043085 positive regulation of catalytic activity BP
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043412 macromolecule modification BP
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044093 positive regulation of molecular function BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044451 obsolete nucleoplasm part CC
GO:0044464 obsolete cell part CC
GO:0045786 negative regulation of cell cycle BP
GO:0045934 negative regulation of nucleobase-containing compound metabolic process BP
GO:0048518 positive regulation of biological process BP
GO:0048519 negative regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0048523 negative regulation of cellular process BP
GO:0048856 anatomical structure development BP
GO:0050789 regulation of biological process BP
GO:0050790 regulation of catalytic activity BP
GO:0050794 regulation of cellular process BP
GO:0051052 regulation of DNA metabolic process BP
GO:0051053 negative regulation of DNA metabolic process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051173 positive regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051247 positive regulation of protein metabolic process BP
GO:0051338 regulation of transferase activity BP
GO:0051347 positive regulation of transferase activity BP
GO:0051438 regulation of ubiquitin-protein transferase activity BP
GO:0051443 positive regulation of ubiquitin-protein transferase activity BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0051726 regulation of cell cycle BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065007 biological regulation BP
GO:0065009 regulation of molecular function BP
GO:0070013 intracellular organelle lumen CC
GO:0070647 protein modification by small protein conjugation or removal BP
GO:0070979 protein K11-linked ubiquitination BP
GO:0071704 organic substance metabolic process BP
GO:0080090 regulation of primary metabolic process BP
GO:0090329 regulation of DNA-templated DNA replication BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1902494 catalytic complex CC
GO:1903320 regulation of protein modification by small protein conjugation or removal BP
GO:1903322 positive regulation of protein modification by small protein conjugation or removal BP
GO:1904666 regulation of ubiquitin protein ligase activity BP
GO:1904668 positive regulation of ubiquitin protein ligase activity BP
GO:1990234 transferase complex CC
GO:2000104 negative regulation of DNA-templated DNA replication BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000113 negative regulation of cellular macromolecule biosynthetic process BP
KEGG Term Name Description
map04120 Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.