Basic Information
Gene ID
Position
Chr13:104065132-104067452 (+)
2320bp
Gene Type
gene
Gene Description (Protein Product)
Belongs to the ubiquitin-conjugating enzyme family
Organism
Also AS AT3G20060

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
CSS0043752.g complex subunit 11
CSS0049196.g ubiquitin-NEDD8-like protein
CSS0045129.g Belongs to the ubiquitin-conjugating enzyme family
Regulatory gene
CSS0000220.g Transcription factor
CSS0000442.g transcription factor
CSS0000465.g SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains

Load All Networks

Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000209 protein polyubiquitination BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0004842 ubiquitin-protein transferase activity MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0006464 protein modification process BP
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0007088 regulation of mitotic nuclear division BP
GO:0007346 regulation of mitotic cell cycle BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008283 cell population proliferation BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009987 cellular process BP
GO:0010498 proteasomal protein catabolic process BP
GO:0010564 regulation of cell cycle process BP
GO:0010965 regulation of mitotic sister chromatid separation BP
GO:0016567 protein ubiquitination BP
GO:0016740 transferase activity MF
GO:0019538 protein metabolic process BP
GO:0019787 ubiquitin-like protein transferase activity MF
GO:0019899 enzyme binding MF
GO:0019941 modification-dependent protein catabolic process BP
GO:0030071 regulation of mitotic metaphase/anaphase transition BP
GO:0030163 protein catabolic process BP
GO:0031145 anaphase-promoting complex-dependent catabolic process BP
GO:0031625 ubiquitin protein ligase binding MF
GO:0032446 protein modification by small protein conjugation BP
GO:0033043 regulation of organelle organization BP
GO:0033044 regulation of chromosome organization BP
GO:0033045 regulation of sister chromatid segregation BP
GO:0033047 regulation of mitotic sister chromatid segregation BP
GO:0036211 protein modification process BP
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044389 ubiquitin-like protein ligase binding MF
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0051128 regulation of cellular component organization BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0051726 regulation of cell cycle BP
GO:0051783 regulation of nuclear division BP
GO:0051983 regulation of chromosome segregation BP
GO:0061630 ubiquitin protein ligase activity MF
GO:0061659 ubiquitin-like protein ligase activity MF
GO:0065007 biological regulation BP
GO:0070647 protein modification by small protein conjugation or removal BP
GO:0071704 organic substance metabolic process BP
GO:0140096 catalytic activity, acting on a protein MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901987 regulation of cell cycle phase transition BP
GO:1901990 regulation of mitotic cell cycle phase transition BP
GO:1902099 regulation of metaphase/anaphase transition of cell cycle BP
GO:1905818 regulation of chromosome separation BP
KEGG Term Name Description
map04120 Ubiquitin mediated proteolysis Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.