Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004838 | L-tyrosine:2-oxoglutarate aminotransferase activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005829 | cytosol | CC |
| GO:0006082 | organic acid metabolic process | BP |
| GO:0006520 | amino acid metabolic process | BP |
| GO:0006570 | tyrosine metabolic process | BP |
| GO:0006572 | tyrosine catabolic process | BP |
| GO:0006725 | cellular aromatic compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0008483 | transaminase activity | MF |
| GO:0009056 | catabolic process | BP |
| GO:0009063 | amino acid catabolic process | BP |
| GO:0009072 | aromatic amino acid metabolic process | BP |
| GO:0009074 | aromatic amino acid family catabolic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0016054 | organic acid catabolic process | BP |
| GO:0016740 | transferase activity | MF |
| GO:0016769 | transferase activity, transferring nitrogenous groups | MF |
| GO:0019439 | aromatic compound catabolic process | BP |
| GO:0019752 | carboxylic acid metabolic process | BP |
| GO:0043436 | oxoacid metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044248 | cellular catabolic process | BP |
| GO:0044281 | small molecule metabolic process | BP |
| GO:0044282 | small molecule catabolic process | BP |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0046395 | carboxylic acid catabolic process | BP |
| GO:0070547 | L-tyrosine aminotransferase activity | MF |
| GO:0071704 | organic substance metabolic process | BP |
| GO:1901360 | organic cyclic compound metabolic process | BP |
| GO:1901361 | organic cyclic compound catabolic process | BP |
| GO:1901564 | organonitrogen compound metabolic process | BP |
| GO:1901565 | organonitrogen compound catabolic process | BP |
| GO:1901575 | organic substance catabolic process | BP |
| GO:1901605 | alpha-amino acid metabolic process | BP |
| GO:1901606 | alpha-amino acid catabolic process | BP |
| KEGG Term | Name | Description |
|---|---|---|
| map01110 | Biosynthesis of secondary metabolites | - |
| map01100 | Metabolic pathways | - |
| map00960 | Tropane, piperidine and pyridine alkaloid biosynthesis | - |
| map00950 | Isoquinoline alkaloid biosynthesis | Isoquinoline alkaloids are tyrosine-derived plant alkaloids with an isoquinoline skeleton. Among them benzylisoquinoline alkaloids form an important group with potent pharmacological activity, including analgesic compounds of morphine and codeine, and anti-infective agents of berberine, palmatine, and magnoflorine. Biosynthesis of isoquinoline alkaloids proceeds via decarboxylation of tyrosine or DOPA to yield dopamine, which together with 4-hydroxyphenylacetaldehyde, an aldehyde derived from tyrosine, is converted to reticuline, an important precursor of various benzylisoquinoline alkaloids. |
| map00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | - |
| map00360 | Phenylalanine metabolism | - |
| map00350 | Tyrosine metabolism | - |
| map00270 | Cysteine and methionine metabolism | Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034]. |
| map00130 | Ubiquinone and other terpenoid-quinone biosynthesis | Ubiquinone (UQ), also called coenzyme Q, and plastoquinone (PQ) are electron carriers in oxidative phosphorylation and photosynthesis, respectively. The quinoid nucleus of ubiquinone is derived from the shikimate pathway; 4-hydroxybenzoate is directly formed from chorismate in bacteria, while it can be formed from either chorismate or tyrosine in yeast. The following biosynthesis of terpenoid moiety involves reactions of prenylation, decarboxylation, and three hydroxylations alternating with three methylations. The order of these reactions are somewhat different between bacteria and yeast. Phylloquinone (vitamin K1), menaquinone (vitamin K2), and tocopherol (vitamin E) are fat-soluble vitamins. Phylloquinone is a compound present in all photosynthetic plants serving as a cofactor for photosystem I-mediated electron transport. Menaquinone is an obligatory component of the electron-transfer pathway in bacteria. |