Basic Information
Gene ID
Position
Chr7:171662480-171666802 (+)
4322bp
Gene Type
gene
Gene Description (Protein Product)
mediator of RNA polymerase II transcription subunit
Organism
Also AS AT5G52470

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
CSS0048459.g Nucleolar protein
CSS0050028.g Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly
CSS0049967.g H ACA ribonucleoprotein complex subunit 4
Regulatory gene
CSS0000128.g tesmin tso1-like cxc
CSS0004360.g Dof zinc finger protein
CSS0004951.g dof zinc finger protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000154 rRNA modification BP
GO:0000494 box C/D RNA 3'-end processing BP
GO:0001510 RNA methylation BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003723 RNA binding MF
GO:0003824 catalytic activity MF
GO:0004518 nuclease activity MF
GO:0004540 ribonuclease activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005730 nucleolus CC
GO:0005732 sno(s)RNA-containing ribonucleoprotein complex CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006325 chromatin organization BP
GO:0006364 rRNA processing BP
GO:0006396 RNA processing BP
GO:0006464 protein modification process BP
GO:0006479 protein methylation BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006996 organelle organization BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008168 methyltransferase activity MF
GO:0008170 N-methyltransferase activity MF
GO:0008173 RNA methyltransferase activity MF
GO:0008213 protein alkylation BP
GO:0008276 protein methyltransferase activity MF
GO:0008649 rRNA methyltransferase activity MF
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity MF
GO:0009451 RNA modification BP
GO:0009987 cellular process BP
GO:0010467 gene expression BP
GO:0015030 Cajal body CC
GO:0016020 membrane CC
GO:0016043 cellular component organization BP
GO:0016070 RNA metabolic process BP
GO:0016072 rRNA metabolic process BP
GO:0016074 sno(s)RNA metabolic process BP
GO:0016569 obsolete covalent chromatin modification BP
GO:0016570 histone modification BP
GO:0016571 histone methylation BP
GO:0016592 mediator complex CC
GO:0016604 nuclear body CC
GO:0016740 transferase activity MF
GO:0016741 transferase activity, transferring one-carbon groups MF
GO:0016787 hydrolase activity MF
GO:0016788 hydrolase activity, acting on ester bonds MF
GO:0018364 peptidyl-glutamine methylation BP
GO:0019538 protein metabolic process BP
GO:0022613 ribonucleoprotein complex biogenesis BP
GO:0030515 snoRNA binding MF
GO:0030684 preribosome CC
GO:0031123 RNA 3'-end processing BP
GO:0031126 sno(s)RNA 3'-end processing BP
GO:0031167 rRNA methylation BP
GO:0031428 box C/D RNP complex CC
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032040 small-subunit processome CC
GO:0032259 methylation BP
GO:0032991 protein-containing complex CC
GO:0033967 box C/D RNA metabolic process BP
GO:0034470 ncRNA processing BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034660 ncRNA metabolic process BP
GO:0034963 box C/D RNA processing BP
GO:0036009 protein-glutamine N-methyltransferase activity MF
GO:0036211 protein modification process BP
GO:0042054 histone methyltransferase activity MF
GO:0042254 ribosome biogenesis BP
GO:0043144 sno(s)RNA processing BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043412 macromolecule modification BP
GO:0043414 macromolecule methylation BP
GO:0043628 regulatory ncRNA 3'-end processing BP
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044267 protein metabolic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044451 obsolete nucleoplasm part CC
GO:0044452 obsolete nucleolar part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0051276 chromosome organization BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0090501 RNA phosphodiester bond hydrolysis BP
GO:0097159 organic cyclic compound binding MF
GO:0140096 catalytic activity, acting on a protein MF
GO:0140098 catalytic activity, acting on RNA MF
GO:0140102 catalytic activity, acting on a rRNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1990258 histone glutamine methylation BP
GO:1990259 histone glutamine N-methyltransferase activity MF
GO:1990904 ribonucleoprotein complex CC
KEGG Term Name Description
map03008 Ribosome biogenesis in eukaryotes Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage.