PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	CSS0049709.g View in Genome Browser
Position	Chr1:13607413-13614523 (+) 7110bp
Gene Type	gene
Gene Description (Protein Product)	Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids
Organism	Camellia sinensis
Also AS	AT3G54250

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	CSS0049885.g Mevalonate kinase
Regulatory gene	CSS0000128.g tesmin tso1-like cxc CSS0004360.g Dof zinc finger protein CSS0004951.g dof zinc finger protein

Load All Networks

Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004163	diphosphomevalonate decarboxylase activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005737	cytoplasm	CC
GO:0005777	peroxisome	CC
GO:0005829	cytosol	CC
GO:0006066	alcohol metabolic process	BP
GO:0006084	acetyl-CoA metabolic process	BP
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006163	purine nucleotide metabolic process	BP
GO:0006464	protein modification process	BP
GO:0006486	protein glycosylation	BP
GO:0006487	protein N-linked glycosylation	BP
GO:0006488	dolichol-linked oligosaccharide biosynthetic process	BP
GO:0006489	dolichyl diphosphate biosynthetic process	BP
GO:0006490	oligosaccharide-lipid intermediate biosynthetic process	BP
GO:0006629	lipid metabolic process	BP
GO:0006637	acyl-CoA metabolic process	BP
GO:0006644	phospholipid metabolic process	BP
GO:0006694	steroid biosynthetic process	BP
GO:0006695	cholesterol biosynthetic process	BP
GO:0006720	isoprenoid metabolic process	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006732	obsolete coenzyme metabolic process	BP
GO:0006753	nucleoside phosphate metabolic process	BP
GO:0006790	sulfur compound metabolic process	BP
GO:0006793	phosphorus metabolic process	BP
GO:0006796	phosphate-containing compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008202	steroid metabolic process	BP
GO:0008203	cholesterol metabolic process	BP
GO:0008284	positive regulation of cell population proliferation	BP
GO:0008299	isoprenoid biosynthetic process	BP
GO:0008610	lipid biosynthetic process	BP
GO:0008654	phospholipid biosynthetic process	BP
GO:0009058	biosynthetic process	BP
GO:0009059	macromolecule biosynthetic process	BP
GO:0009100	glycoprotein metabolic process	BP
GO:0009101	glycoprotein biosynthetic process	BP
GO:0009117	nucleotide metabolic process	BP
GO:0009150	purine ribonucleotide metabolic process	BP
GO:0009240	isopentenyl diphosphate biosynthetic process	BP
GO:0009259	ribonucleotide metabolic process	BP
GO:0009889	regulation of biosynthetic process	BP
GO:0009987	cellular process	BP
GO:0016125	sterol metabolic process	BP
GO:0016126	sterol biosynthetic process	BP
GO:0016829	lyase activity	MF
GO:0016830	carbon-carbon lyase activity	MF
GO:0016831	carboxy-lyase activity	MF
GO:0019216	regulation of lipid metabolic process	BP
GO:0019218	regulation of steroid metabolic process	BP
GO:0019222	regulation of metabolic process	BP
GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	BP
GO:0019538	protein metabolic process	BP
GO:0019637	organophosphate metabolic process	BP
GO:0019693	ribose phosphate metabolic process	BP
GO:0030544	Hsp70 protein binding	MF
GO:0031072	heat shock protein binding	MF
GO:0033865	nucleoside bisphosphate metabolic process	BP
GO:0033875	ribonucleoside bisphosphate metabolic process	BP
GO:0034032	purine nucleoside bisphosphate metabolic process	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034645	cellular macromolecule biosynthetic process	BP
GO:0035383	thioester metabolic process	BP
GO:0036211	protein modification process	BP
GO:0042127	regulation of cell population proliferation	BP
GO:0042579	microbody	CC
GO:0042802	identical protein binding	MF
GO:0042803	protein homodimerization activity	MF
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043412	macromolecule modification	BP
GO:0043413	macromolecule glycosylation	BP
GO:0043603	amide metabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044249	cellular biosynthetic process	BP
GO:0044255	cellular lipid metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044281	small molecule metabolic process	BP
GO:0044283	small molecule biosynthetic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0045540	regulation of cholesterol biosynthetic process	BP
GO:0046165	alcohol biosynthetic process	BP
GO:0046465	dolichyl diphosphate metabolic process	BP
GO:0046483	heterocycle metabolic process	BP
GO:0046490	isopentenyl diphosphate metabolic process	BP
GO:0046890	regulation of lipid biosynthetic process	BP
GO:0046983	protein dimerization activity	MF
GO:0048518	positive regulation of biological process	BP
GO:0048522	positive regulation of cellular process	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0050810	regulation of steroid biosynthetic process	BP
GO:0051186	obsolete cofactor metabolic process	BP
GO:0055086	nucleobase-containing small molecule metabolic process	BP
GO:0062012	regulation of small molecule metabolic process	BP
GO:0065007	biological regulation	BP
GO:0070085	glycosylation	BP
GO:0071704	organic substance metabolic process	BP
GO:0072521	purine-containing compound metabolic process	BP
GO:0080090	regulation of primary metabolic process	BP
GO:0090181	regulation of cholesterol metabolic process	BP
GO:0090407	organophosphate biosynthetic process	BP
GO:0106118	regulation of sterol biosynthetic process	BP
GO:1901135	carbohydrate derivative metabolic process	BP
GO:1901137	carbohydrate derivative biosynthetic process	BP
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901362	organic cyclic compound biosynthetic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901566	organonitrogen compound biosynthetic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1901615	organic hydroxy compound metabolic process	BP
GO:1901617	organic hydroxy compound biosynthetic process	BP
GO:1902652	secondary alcohol metabolic process	BP
GO:1902653	secondary alcohol biosynthetic process	BP
GO:1902930	regulation of alcohol biosynthetic process	BP

KEGG Term	Name	Description
map01110	Biosynthesis of secondary metabolites	-
map01100	Metabolic pathways	-
map00900	Terpenoid backbone biosynthesis	Terpenoids, also known as isoprenoids, are a large class of natural products consisting of isoprene (C5) units. There are two biosynthetic pathways, the mevalonate pathway [MD:M00095] and the non-mevalonate pathway or the MEP/DOXP pathway [MD:M00096], for the terpenoid building blocks: isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). The action of prenyltransferases then generates higher-order building blocks: geranyl diphosphate (GPP), farsenyl diphosphate (FPP), and geranylgeranyl diphosphate (GGPP), which are the precursors of monoterpenoids (C10), sesquiterpenoids (C15), and diterpenoids (C20), respectively. Condensation of these building blocks gives rise to the precursors of sterols (C30) and carotenoids (C40). The MEP/DOXP pathway is absent in higher animals and fungi, but in green plants the MEP/DOXP and mevalonate pathways co-exist in separate cellular compartments. The MEP/DOXP pathway, operating in the plastids, is responsible for the formation of essential oil monoterpenes and linalyl acetate, some sesquiterpenes, diterpenes, and carotenoids and phytol. The mevalonate pathway, operating in the cytosol, gives rise to triterpenes, sterols, and most sesquiterpenes.