Basic Information
Gene ID
Position
Chr3:73076678-73079942 (-)
3264bp
Gene Type
gene
Gene Description (Protein Product)
"The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg
Organism
Also AS AT1G56450

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
CSS0050250.g 26S proteasome non-ATPase regulatory subunit 13
CSS0050163.g The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH
Regulatory gene
CSS0004360.g Dof zinc finger protein
CSS0004951.g dof zinc finger protein
CSS0012691.g Dof zinc finger protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000502 proteasome complex CC
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0005839 proteasome core complex CC
GO:0005840 ribosome CC
GO:0006950 response to stress BP
GO:0006970 response to osmotic stress BP
GO:0008150 biological_process BP
GO:0009628 response to abiotic stimulus BP
GO:0009651 response to salt stress BP
GO:0010035 response to inorganic substance BP
GO:0010038 response to metal ion BP
GO:0019774 proteasome core complex, beta-subunit complex CC
GO:0022626 cytosolic ribosome CC
GO:0032991 protein-containing complex CC
GO:0042221 response to chemical BP
GO:0043226 organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044445 obsolete cytosolic part CC
GO:0044464 obsolete cell part CC
GO:0046686 response to cadmium ion BP
GO:0050896 response to stimulus BP
GO:1902494 catalytic complex CC
GO:1905368 peptidase complex CC
GO:1905369 endopeptidase complex CC
GO:1990904 ribonucleoprotein complex CC
KEGG Term Name Description
map03050 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.