Basic Information
Gene ID
geneMaker00026017
Position
GWHBGXC00000011:38232621-38235930 (-)
3309bp
Gene Type
gene
Gene Description (Protein Product)
Homocysteine s-methyltransferase
Organism
Also AS AT3G25900

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
geneMaker00029379 Cobalamin-independent synthase; Catalytic domain
geneMaker00027392 Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors
geneMaker00027381 sarcosine oxidase

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0000096 sulfur amino acid metabolic process BP
GO:0000097 sulfur amino acid biosynthetic process BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0006082 organic acid metabolic process BP
GO:0006520 amino acid metabolic process BP
GO:0006555 methionine metabolic process BP
GO:0006790 sulfur compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008168 methyltransferase activity MF
GO:0008172 S-methyltransferase activity MF
GO:0008652 amino acid biosynthetic process BP
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity MF
GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity MF
GO:0009058 biosynthetic process BP
GO:0009066 aspartate family amino acid metabolic process BP
GO:0009067 aspartate family amino acid biosynthetic process BP
GO:0009086 methionine biosynthetic process BP
GO:0009987 cellular process BP
GO:0016053 organic acid biosynthetic process BP
GO:0016740 transferase activity MF
GO:0016741 transferase activity, transferring one-carbon groups MF
GO:0019752 carboxylic acid metabolic process BP
GO:0032259 methylation BP
GO:0043436 oxoacid metabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044272 sulfur compound biosynthetic process BP
GO:0044281 small molecule metabolic process BP
GO:0044283 small molecule biosynthetic process BP
GO:0046394 carboxylic acid biosynthetic process BP
GO:0071704 organic substance metabolic process BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901566 organonitrogen compound biosynthetic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1901605 alpha-amino acid metabolic process BP
GO:1901607 alpha-amino acid biosynthetic process BP
KEGG Term Name Description
map01110 Biosynthesis of secondary metabolites -
map01100 Metabolic pathways -
map00270 Cysteine and methionine metabolism Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].