Basic Information
Gene ID
Ciclev10020733m.g.v1.0
Position
scaffold_3:49445681-49449255 (+)
3574bp
Gene Type
gene
Gene Description (Protein Product)
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors; where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state; facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently; the homodimer reverts towards the open dimer state; lowering its affinity for the membrane-bound receptor; and returning it to the cytosol to initiate a new round of targeting
Organism
Also AS AT1G01910CICLE_v10020733mg

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Ciclev10023012m.g.v1.0 Gibberellin-regulated protein
Ciclev10032463m.g.v1.0 Signal recognition particle receptor subunit
Ciclev10032978m.g.v1.0 Peptidyl-prolyl cis-trans isomerase
Regulatory gene
Ciclev10000065m.g.v1.0 Protein ALWAYS EARLY
Ciclev10000454m.g.v1.0 Trihelix transcription factor
Ciclev10000593m.g.v1.0 Trihelix transcription factor

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail