PPGR - Gene Detail

Basic Information

Gene ID	Ciclev10023873m.g.v1.0 View in Genome Browser
Position	scaffold_3:24732324-24734809 (-) 2485bp
Gene Type	gene
Gene Description (Protein Product)	GPI ethanolamine phosphate transferase
Organism	Citrus clementina
Also AS	AT5G17250CICLE_v10023873mg

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

Ciclev10024315m.g.v1.0 Gpi-anchor transamidase

Ciclev10029246m.g.v1.0 Catalyzes the third of the four reactions of the long- chain fatty acids elongation cycle. This endoplasmic reticulum- bound enzymatic process; allows the addition of two carbons to the chain of long- and very long-chain fatty acids VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2;3-enoyl-CoA; within each cycle of fatty acid elongation. Thereby; it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators

Ciclev10025838m.g.v1.0 Belongs to the fatty acid desaturase type 1 family

Regulatory gene

Ciclev10000225m.g.v1.0 B3 domain-containing

Ciclev10000881m.g.v1.0 B3 domain-containing protein

Ciclev10001063m.g.v1.0 B3 domain-containing protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

KEGG Term	Name	Description
map01100	Metabolic pathways	-
map00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	Cell surface proteins can be attached to the cell membrane via the glycolipid structure called glycosylphosphatidylinositol (GPI) anchor. Hundreds of GPI-anchored proteins have been identified in many eukaryotes ranging from protozoa and fungi to mammals. All protein-linked GPI anchors share a common core structure, characterized by the substructure Man (a1-4) GlcN (a1-6) myo-inositol-1P-lipid. Biosynthesis of GPI anchors proceeds in three stages: (i) preassembly of a GPI precursor in the ER membrane, (ii) attachment of the GPI to the C-terminus of a newly synthesized protein in the lumen of the ER, and (iii) lipid remodeling and/or carbohydrate side-chain modifications in the ER and the Golgi. Defects of GPI anchor biosynthesis gene result in a genetic disorder, paroxysmal nocturnal hemoglobinuria.