PPGR - Gene Detail

Basic Information

Gene ID	Ciclev10031660m.g.v1.0 View in Genome Browser
Position	scaffold_4:3421942-3425673 (-) 3731bp
Gene Type	gene
Gene Description (Protein Product)	Macrophage erythroblast
Organism	Citrus clementina
Also AS	AT3G55070CICLE_v10031660mg

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

Ciclev10033070m.g.v1.0 Belongs to the yippee family

Ciclev10032098m.g.v1.0 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is involved in protein synthesis of a specialized repertoire of mRNAs and; together with other initiation factors; stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation

Ciclev10032763m.g.v1.0 Mitotic spindle checkpoint protein

Regulatory gene

Ciclev10000225m.g.v1.0 B3 domain-containing

Ciclev10000850m.g.v1.0 Protein SENSITIVE TO PROTON RHIZOTOXICITY

Ciclev10000881m.g.v1.0 B3 domain-containing protein

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005737	cytoplasm	CC
GO:0005829	cytosol	CC
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009987	cellular process	BP
GO:0010498	proteasomal protein catabolic process	BP
GO:0019538	protein metabolic process	BP
GO:0019941	modification-dependent protein catabolic process	BP
GO:0030163	protein catabolic process	BP
GO:0032991	protein-containing complex	CC
GO:0034657	GID complex	CC
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044424	obsolete intracellular part	CC
GO:0044444	obsolete cytoplasmic part	CC
GO:0044464	obsolete cell part	CC
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0071704	organic substance metabolic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901575	organic substance catabolic process	BP

KEGG Term	Name	Description
map03015	mRNA surveillance pathway	The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins.