PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	orange1.1g048648m.g.v1.1 View in Genome Browser
Position	scaffold00015:950634-953612 (+) 2978bp
Gene Type	gene
Gene Description (Protein Product)	histone ubiquitination
Organism	Citrus sinensis
Also AS	AT2G02760CICLE_v10013448mg

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Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	orange1.1g048693m.g.v1.1 Belongs to the heat shock protein 70 family
Regulatory gene	orange1.1g000304m.g.v1.1 SANT SWI3; ADA2; N-CoR and TFIIIB'' DNA-binding domains orange1.1g000392m.g.v1.1 lysine-specific demethylase orange1.1g001409m.g.v1.1 Myb-like protein L

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0000151	ubiquitin ligase complex	CC
GO:0000209	protein polyubiquitination	BP
GO:0000228	nuclear chromosome	CC
GO:0000785	chromatin	CC
GO:0000790	chromatin	CC
GO:0000792	heterochromatin	CC
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0004842	ubiquitin-protein transferase activity	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0005654	nucleoplasm	CC
GO:0005657	replication fork	CC
GO:0005694	chromosome	CC
GO:0005737	cytoplasm	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006281	DNA repair	BP
GO:0006301	postreplication repair	BP
GO:0006325	chromatin organization	BP
GO:0006464	protein modification process	BP
GO:0006508	proteolysis	BP
GO:0006511	ubiquitin-dependent protein catabolic process	BP
GO:0006513	protein monoubiquitination	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0006996	organelle organization	BP
GO:0007154	cell communication	BP
GO:0007165	signal transduction	BP
GO:0007166	cell surface receptor signaling pathway	BP
GO:0007267	cell-cell signaling	BP
GO:0007276	gamete generation	BP
GO:0007283	spermatogenesis	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009056	catabolic process	BP
GO:0009057	macromolecule catabolic process	BP
GO:0009314	response to radiation	BP
GO:0009411	response to UV	BP
GO:0009416	response to light stimulus	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009966	regulation of signal transduction	BP
GO:0009968	negative regulation of signal transduction	BP
GO:0009987	cellular process	BP
GO:0010498	proteasomal protein catabolic process	BP
GO:0010646	regulation of cell communication	BP
GO:0010648	negative regulation of cell communication	BP
GO:0016043	cellular component organization	BP
GO:0016055	Wnt signaling pathway	BP
GO:0016567	protein ubiquitination	BP
GO:0016569	obsolete covalent chromatin modification	BP
GO:0016570	histone modification	BP
GO:0016574	histone ubiquitination	BP
GO:0016740	transferase activity	MF
GO:0019538	protein metabolic process	BP
GO:0019787	ubiquitin-like protein transferase activity	MF
GO:0019899	enzyme binding	MF
GO:0019941	modification-dependent protein catabolic process	BP
GO:0019953	sexual reproduction	BP
GO:0022414	reproductive process	BP
GO:0023051	regulation of signaling	BP
GO:0023052	signaling	BP
GO:0023057	negative regulation of signaling	BP
GO:0030163	protein catabolic process	BP
GO:0031371	ubiquitin conjugating enzyme complex	CC
GO:0031625	ubiquitin protein ligase binding	MF
GO:0031647	regulation of protein stability	BP
GO:0031974	membrane-enclosed lumen	CC
GO:0031981	nuclear lumen	CC
GO:0032446	protein modification by small protein conjugation	BP
GO:0032501	multicellular organismal process	BP
GO:0032504	multicellular organism reproduction	BP
GO:0032991	protein-containing complex	CC
GO:0033503	HULC complex	CC
GO:0033522	histone H2A ubiquitination	BP
GO:0033554	cellular response to stress	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0036211	protein modification process	BP
GO:0042221	response to chemical	BP
GO:0042493	response to xenobiotic stimulus	BP
GO:0042769	obsolete DNA damage response, detection of DNA damage	BP
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043228	non-membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043232	intracellular non-membrane-bounded organelle	CC
GO:0043233	organelle lumen	CC
GO:0043412	macromolecule modification	BP
GO:0043632	modification-dependent macromolecule catabolic process	BP
GO:0043949	regulation of cAMP-mediated signaling	BP
GO:0043951	negative regulation of cAMP-mediated signaling	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044248	cellular catabolic process	BP
GO:0044257	protein catabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044265	cellular macromolecule catabolic process	BP
GO:0044267	protein metabolic process	BP
GO:0044389	ubiquitin-like protein ligase binding	MF
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044427	obsolete chromosomal part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044454	obsolete nuclear chromosome part	CC
GO:0044464	obsolete cell part	CC
GO:0044703	multi-organism reproductive process	BP
GO:0046483	heterocycle metabolic process	BP
GO:0048232	male gamete generation	BP
GO:0048519	negative regulation of biological process	BP
GO:0048523	negative regulation of cellular process	BP
GO:0048583	regulation of response to stimulus	BP
GO:0048585	negative regulation of response to stimulus	BP
GO:0048609	multicellular organismal reproductive process	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0050821	protein stabilization	BP
GO:0050896	response to stimulus	BP
GO:0051276	chromosome organization	BP
GO:0051603	proteolysis involved in protein catabolic process	BP
GO:0051606	detection of stimulus	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051716	cellular response to stimulus	BP
GO:0051865	protein autoubiquitination	BP
GO:0060070	canonical Wnt signaling pathway	BP
GO:0061630	ubiquitin protein ligase activity	MF
GO:0061659	ubiquitin-like protein ligase activity	MF
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0070013	intracellular organelle lumen	CC
GO:0070534	protein K63-linked ubiquitination	BP
GO:0070647	protein modification by small protein conjugation or removal	BP
GO:0070936	protein K48-linked ubiquitination	BP
GO:0070979	protein K11-linked ubiquitination	BP
GO:0071704	organic substance metabolic process	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0140096	catalytic activity, acting on a protein	MF
GO:0198738	cell-cell signaling by wnt	BP
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901564	organonitrogen compound metabolic process	BP
GO:1901565	organonitrogen compound catabolic process	BP
GO:1901575	organic substance catabolic process	BP
GO:1902494	catalytic complex	CC
GO:1902531	regulation of intracellular signal transduction	BP
GO:1902532	negative regulation of intracellular signal transduction	BP
GO:1905114	cell surface receptor signaling pathway involved in cell-cell signaling	BP
GO:1990234	transferase complex	CC

KEGG Term	Name	Description
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.
map04120	Ubiquitin mediated proteolysis	Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates.