Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
orange1.1g048704m.g.v1.1
View in Genome Browser
Position
scaffold00154:239069-242766 (-)
3697bp
Gene Type
gene
Gene Description (Protein Product)
DNA topoisomerase type I activity
Organism
Citrus sinensis
Also AS AT2G32000CICLE_v10005848mg

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
orange1.1g048832m.g.v1.1 Werner syndrome-like exonuclease
Regulatory gene
orange1.1g001317m.g.v1.1 Squamosa promoter-binding-like protein
orange1.1g001971m.g.v1.1 Squamosa promoter-binding-like protein
orange1.1g002868m.g.v1.1 Squamosa promoter-binding-like protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000793 condensed chromosome CC
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003723 RNA binding MF
GO:0003729 mRNA binding MF
GO:0003824 catalytic activity MF
GO:0003916 DNA topoisomerase activity MF
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005694 chromosome CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006265 DNA topological change BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006996 organelle organization BP
GO:0007059 chromosome segregation BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009987 cellular process BP
GO:0016043 cellular component organization BP
GO:0016853 isomerase activity MF
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0044087 regulation of cellular component biogenesis BP
GO:0044089 positive regulation of cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0048518 positive regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050793 regulation of developmental process BP
GO:0050794 regulation of cellular process BP
GO:0050803 regulation of synapse structure or activity BP
GO:0050807 regulation of synapse organization BP
GO:0051094 positive regulation of developmental process BP
GO:0051128 regulation of cellular component organization BP
GO:0051130 positive regulation of cellular component organization BP
GO:0051239 regulation of multicellular organismal process BP
GO:0051240 positive regulation of multicellular organismal process BP
GO:0051276 chromosome organization BP
GO:0051960 regulation of nervous system development BP
GO:0051962 positive regulation of nervous system development BP
GO:0051963 regulation of synapse assembly BP
GO:0051965 positive regulation of synapse assembly BP
GO:0065007 biological regulation BP
GO:0065008 regulation of biological quality BP
GO:0071103 DNA conformation change BP
GO:0071704 organic substance metabolic process BP
GO:0071840 cellular component organization or biogenesis BP
GO:0090304 nucleic acid metabolic process BP
GO:0097159 organic cyclic compound binding MF
GO:0140097 catalytic activity, acting on DNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901363 heterocyclic compound binding MF
GO:2000026 regulation of multicellular organismal development BP
KEGG Term Name Description
map03440 Homologous recombination Homologous recombination (HR) is essential for the accurate repair of DNA double-strand breaks (DSBs), potentially lethal lesions. HR takes place in the late S-G2 phase of the cell cycle and involves the generation of a single-stranded region of DNA, followed by strand invasion, formation of a Holliday junction, DNA synthesis using the intact strand as a template, branch migration and resolution. It is investigated that RecA/Rad51 family proteins play a central role. The breast cancer susceptibility protein Brca2 and the RecQ helicase BLM (Bloom syndrome mutated) are tumor suppressors that maintain genome integrity, at least in part, through HR.