Basic Information
Gene ID
JcaChr15G10118.g
Position
chr15:1267879-1273490 (-)
5611bp
Gene Type
gene
Gene Description (Protein Product)
tRNA pseudouridine synthase
Organism
Also AS AT1G34150

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JcaChr15G11960.g Putative sugar-binding N-terminal domain
JcaChr15G11959.g Putative sugar-binding N-terminal domain
JcaChr15G10491.g Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product
Regulatory gene
JcaChr01G10428.g ZINC FINGER protein
JcaChr01G10490.g lysine-specific demethylase
JcaChr01G11180.g ZINC FINGER protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
GO Term Description GO Category
GO:0001522 pseudouridine synthesis BP
GO:0003674 molecular_function MF
GO:0003824 catalytic activity MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006396 RNA processing BP
GO:0006399 tRNA metabolic process BP
GO:0006400 tRNA modification BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008033 tRNA processing BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009451 RNA modification BP
GO:0009982 pseudouridine synthase activity MF
GO:0009987 cellular process BP
GO:0010467 gene expression BP
GO:0016070 RNA metabolic process BP
GO:0016071 mRNA metabolic process BP
GO:0016556 mRNA modification BP
GO:0016853 isomerase activity MF
GO:0016866 intramolecular transferase activity MF
GO:0031119 tRNA pseudouridine synthesis BP
GO:0034470 ncRNA processing BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034660 ncRNA metabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043412 macromolecule modification BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0046483 heterocycle metabolic process BP
GO:0071704 organic substance metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1990481 mRNA pseudouridine synthesis BP