Basic Information
Gene ID
JhiChr12G11184.g
Position
chr12:17165164-17171791 (-)
6627bp
Gene Type
gene
Gene Description (Protein Product)
DNA repair helicase
Organism
Also AS AT5G41370

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JhiChr15G11334.g DNA-directed RNA polymerases I, II, and III
JhiChr16G11324.g Pentatricopeptide repeat-containing protein
JhiChr12G11513.g Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase
Regulatory gene
JhiChr05G10706.g Protein BASIC PENTACYSTEINE4-like
JhiChr06G10857.g Protein BASIC PENTACYSTEINE2-like
JhiChr06G10933.g Protein BASIC PENTACYSTEINE6-like

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0008150 biological_process BP
GO:0009314 response to radiation BP
GO:0009411 response to UV BP
GO:0009416 response to light stimulus BP
GO:0009628 response to abiotic stimulus BP
GO:0010224 response to UV-B BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0044424 obsolete intracellular part CC
GO:0044464 obsolete cell part CC
GO:0050896 response to stimulus BP
KEGG Term Name Description
map03420 Nucleotide excision repair Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar.
map03022 Basal transcription factors -