Basic Information
Gene ID
JhiChr14G11512.g
Position
chr14:20301681-20306242 (+)
4561bp
Gene Type
gene
Gene Description (Protein Product)
Telomerase activating protein Est1
Organism
Also AS AT5G19400

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JhiChr15G11558.g H ACA ribonucleoprotein complex subunit 2-like
JhiChr16G10594.g U6 snRNA-associated Sm-like protein
Regulatory gene
JhiChr01G10099.g transcription factor
JhiChr01G10102.g transcription factor
JhiChr01G10343.g Myb-related protein

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000003 reproduction BP
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay BP
GO:0000212 meiotic spindle organization BP
GO:0000226 microtubule cytoskeleton organization BP
GO:0000280 nuclear division BP
GO:0000723 telomere maintenance BP
GO:0000932 P-body CC
GO:0000956 nuclear-transcribed mRNA catabolic process BP
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003723 RNA binding MF
GO:0003824 catalytic activity MF
GO:0004518 nuclease activity MF
GO:0004540 ribonuclease activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005697 telomerase holoenzyme complex CC
GO:0005737 cytoplasm CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006278 RNA-templated DNA biosynthetic process BP
GO:0006401 RNA catabolic process BP
GO:0006402 mRNA catabolic process BP
GO:0006403 RNA localization BP
GO:0006405 RNA export from nucleus BP
GO:0006406 mRNA export from nucleus BP
GO:0006611 protein export from nucleus BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006810 transport BP
GO:0006886 intracellular protein transport BP
GO:0006913 nucleocytoplasmic transport BP
GO:0006996 organelle organization BP
GO:0007004 telomere maintenance via telomerase BP
GO:0007010 cytoskeleton organization BP
GO:0007017 microtubule-based process BP
GO:0007049 cell cycle BP
GO:0007051 spindle organization BP
GO:0008104 protein localization BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009058 biosynthetic process BP
GO:0009059 macromolecule biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009894 regulation of catabolic process BP
GO:0009987 cellular process BP
GO:0010467 gene expression BP
GO:0010468 regulation of gene expression BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0010608 post-transcriptional regulation of gene expression BP
GO:0010629 negative regulation of gene expression BP
GO:0010833 telomere maintenance via telomere lengthening BP
GO:0015031 protein transport BP
GO:0015833 peptide transport BP
GO:0015931 nucleobase-containing compound transport BP
GO:0016043 cellular component organization BP
GO:0016070 RNA metabolic process BP
GO:0016071 mRNA metabolic process BP
GO:0016787 hydrolase activity MF
GO:0016788 hydrolase activity, acting on ester bonds MF
GO:0018130 heterocycle biosynthetic process BP
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019438 aromatic compound biosynthetic process BP
GO:0019439 aromatic compound catabolic process BP
GO:0022402 cell cycle process BP
GO:0022414 reproductive process BP
GO:0022607 cellular component assembly BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031329 regulation of cellular catabolic process BP
GO:0031503 protein-containing complex localization BP
GO:0032200 telomere organization BP
GO:0032991 protein-containing complex CC
GO:0033036 macromolecule localization BP
GO:0034613 protein localization BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034645 cellular macromolecule biosynthetic process BP
GO:0034654 nucleobase-containing compound biosynthetic process BP
GO:0034655 nucleobase-containing compound catabolic process BP
GO:0035770 ribonucleoprotein granule CC
GO:0036464 cytoplasmic ribonucleoprotein granule CC
GO:0042162 telomeric DNA binding MF
GO:0042592 homeostatic process BP
GO:0042886 amide transport BP
GO:0043021 ribonucleoprotein complex binding MF
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043228 non-membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043232 intracellular non-membrane-bounded organelle CC
GO:0043487 regulation of RNA stability BP
GO:0043565 sequence-specific DNA binding MF
GO:0044085 cellular component biogenesis BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044270 cellular nitrogen compound catabolic process BP
GO:0044271 cellular nitrogen compound biosynthetic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044464 obsolete cell part CC
GO:0044877 protein-containing complex binding MF
GO:0045184 establishment of protein localization BP
GO:0046483 heterocycle metabolic process BP
GO:0046700 heterocycle catabolic process BP
GO:0046907 intracellular transport BP
GO:0048285 organelle fission BP
GO:0048519 negative regulation of biological process BP
GO:0050657 nucleic acid transport BP
GO:0050658 RNA transport BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0051028 mRNA transport BP
GO:0051168 nuclear export BP
GO:0051169 nuclear transport BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051179 localization BP
GO:0051225 spindle assembly BP
GO:0051234 establishment of localization BP
GO:0051236 establishment of RNA localization BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051276 chromosome organization BP
GO:0051321 meiotic cell cycle BP
GO:0051641 cellular localization BP
GO:0051649 establishment of localization in cell BP
GO:0060249 anatomical structure homeostasis BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065007 biological regulation BP
GO:0065008 regulation of biological quality BP
GO:0070034 telomerase RNA binding MF
GO:0070727 cellular macromolecule localization BP
GO:0070925 organelle assembly BP
GO:0071166 ribonucleoprotein complex localization BP
GO:0071426 obsolete ribonucleoprotein complex export from nucleus BP
GO:0071427 obsolete mRNA-containing ribonucleoprotein complex export from nucleus BP
GO:0071702 organic substance transport BP
GO:0071704 organic substance metabolic process BP
GO:0071705 nitrogen compound transport BP
GO:0071840 cellular component organization or biogenesis BP
GO:0071897 DNA biosynthetic process BP
GO:0080090 regulation of primary metabolic process BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0090306 meiotic spindle assembly BP
GO:0090501 RNA phosphodiester bond hydrolysis BP
GO:0097159 organic cyclic compound binding MF
GO:0140013 meiotic nuclear division BP
GO:0140098 catalytic activity, acting on RNA MF
GO:1901360 organic cyclic compound metabolic process BP
GO:1901361 organic cyclic compound catabolic process BP
GO:1901362 organic cyclic compound biosynthetic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901575 organic substance catabolic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1903046 meiotic cell cycle process BP
GO:1990904 ribonucleoprotein complex CC
KEGG Term Name Description
map03015 mRNA surveillance pathway The mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go decay (NGD). NMD is a mechanism that eliminates mRNAs containing premature translation-termination codons (PTCs). In vertebrates, PTCs trigger efficient NMD when located upstream of an exon junction complex (EJC). Upf3, together with Upf1 and Upf2, may signal the presence of the PTC to the 5'end of the transcript, resulting in decapping and rapid exonucleolytic digestion of the mRNA. In the NSD pathway, which targets mRNAs lacking termination codons, the ribosome is believed to translate through the 3' untranslated region and stall at the end of the poly(A) tail. NSD involves an eRF3-like protein, Ski7p, which is hypothesized to bind the empty A site of the ribosome and recruit the exosome to degrade the mRNA from the 3' end. NGD targets mRNAs with stalls in translation elongation for endonucleolytic cleavage in a process involving the Dom34 and Hbs1 proteins.