Basic Information
Gene ID
JhiChr15G10327.g
Position
chr15:4252742-4253419 (+)
677bp
Gene Type
gene
Gene Description (Protein Product)
N-glycosylase DNA
Organism
Also AS AT1G21710

Gene Structure

upstream:

Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JhiChr15G11223.g HhH-GPD superfamily base excision DNA repair protein
JhiChr15G10837.g Methyladenine glycosylase
JhiChr16G11443.g Glutamine--fructose-6-phosphate aminotransferase isomerizing
Regulatory gene
JhiChr01G10168.g transcription factor
JhiChr01G10819.g dof zinc finger protein
JhiChr01G11092.g Transcription factor bHLH131-like

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
GO Term Description GO Category
GO:0000702 oxidized base lesion DNA N-glycosylase activity MF
GO:0003674 molecular_function MF
GO:0003676 nucleic acid binding MF
GO:0003677 DNA binding MF
GO:0003684 damaged DNA binding MF
GO:0003824 catalytic activity MF
GO:0004518 nuclease activity MF
GO:0004519 endonuclease activity MF
GO:0005488 binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005654 nucleoplasm CC
GO:0005737 cytoplasm CC
GO:0005739 mitochondrion CC
GO:0006139 nucleobase-containing compound metabolic process BP
GO:0006220 pyrimidine nucleotide metabolic process BP
GO:0006244 pyrimidine nucleotide catabolic process BP
GO:0006259 DNA metabolic process BP
GO:0006281 DNA repair BP
GO:0006282 regulation of DNA repair BP
GO:0006284 base-excision repair BP
GO:0006285 base-excision repair, AP site formation BP
GO:0006289 nucleotide-excision repair BP
GO:0006304 DNA modification BP
GO:0006355 regulation of DNA-templated transcription BP
GO:0006725 cellular aromatic compound metabolic process BP
GO:0006753 nucleoside phosphate metabolic process BP
GO:0006793 phosphorus metabolic process BP
GO:0006796 phosphate-containing compound metabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0006950 response to stress BP
GO:0006974 cellular response to DNA damage stimulus BP
GO:0006979 response to oxidative stress BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity MF
GO:0009056 catabolic process BP
GO:0009058 biosynthetic process BP
GO:0009117 nucleotide metabolic process BP
GO:0009166 nucleotide catabolic process BP
GO:0009219 pyrimidine deoxyribonucleotide metabolic process BP
GO:0009223 pyrimidine deoxyribonucleotide catabolic process BP
GO:0009262 deoxyribonucleotide metabolic process BP
GO:0009264 deoxyribonucleotide catabolic process BP
GO:0009314 response to radiation BP
GO:0009394 2'-deoxyribonucleotide metabolic process BP
GO:0009628 response to abiotic stimulus BP
GO:0009889 regulation of biosynthetic process BP
GO:0009892 negative regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010468 regulation of gene expression BP
GO:0010556 regulation of macromolecule biosynthetic process BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0016363 nuclear matrix CC
GO:0016604 nuclear body CC
GO:0016607 nuclear speck CC
GO:0016787 hydrolase activity MF
GO:0016788 hydrolase activity, acting on ester bonds MF
GO:0016798 hydrolase activity, acting on glycosyl bonds MF
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds MF
GO:0018130 heterocycle biosynthetic process BP
GO:0019104 DNA N-glycosylase activity MF
GO:0019219 regulation of nucleobase-containing compound metabolic process BP
GO:0019222 regulation of metabolic process BP
GO:0019438 aromatic compound biosynthetic process BP
GO:0019439 aromatic compound catabolic process BP
GO:0019637 organophosphate metabolic process BP
GO:0019692 deoxyribose phosphate metabolic process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031326 regulation of cellular biosynthetic process BP
GO:0031974 membrane-enclosed lumen CC
GO:0031981 nuclear lumen CC
GO:0032356 oxidized DNA binding MF
GO:0032357 oxidized purine DNA binding MF
GO:0032991 protein-containing complex CC
GO:0033554 cellular response to stress BP
GO:0033683 obsolete nucleotide-excision repair, DNA incision BP
GO:0034399 nuclear periphery CC
GO:0034404 nucleobase-containing small molecule biosynthetic process BP
GO:0034641 cellular nitrogen compound metabolic process BP
GO:0034654 nucleobase-containing compound biosynthetic process BP
GO:0034655 nucleobase-containing compound catabolic process BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043233 organelle lumen CC
GO:0043412 macromolecule modification BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044249 cellular biosynthetic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044270 cellular nitrogen compound catabolic process BP
GO:0044271 cellular nitrogen compound biosynthetic process BP
GO:0044281 small molecule metabolic process BP
GO:0044283 small molecule biosynthetic process BP
GO:0044422 obsolete organelle part CC
GO:0044424 obsolete intracellular part CC
GO:0044428 obsolete nuclear part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044446 obsolete intracellular organelle part CC
GO:0044451 obsolete nucleoplasm part CC
GO:0044464 obsolete cell part CC
GO:0045007 depurination BP
GO:0045008 depyrimidination BP
GO:0045738 negative regulation of DNA repair BP
GO:0045934 negative regulation of nucleobase-containing compound metabolic process BP
GO:0046386 deoxyribose phosphate catabolic process BP
GO:0046434 organophosphate catabolic process BP
GO:0046483 heterocycle metabolic process BP
GO:0046700 heterocycle catabolic process BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0048583 regulation of response to stimulus BP
GO:0048585 negative regulation of response to stimulus BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051052 regulation of DNA metabolic process BP
GO:0051053 negative regulation of DNA metabolic process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051252 regulation of RNA metabolic process BP
GO:0051716 cellular response to stimulus BP
GO:0055086 nucleobase-containing small molecule metabolic process BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0065007 biological regulation BP
GO:0070013 intracellular organelle lumen CC
GO:0071704 organic substance metabolic process BP
GO:0072527 pyrimidine-containing compound metabolic process BP
GO:0072529 pyrimidine-containing compound catabolic process BP
GO:0080090 regulation of primary metabolic process BP
GO:0080134 regulation of response to stress BP
GO:0080135 regulation of cellular response to stress BP
GO:0090304 nucleic acid metabolic process BP
GO:0090305 nucleic acid phosphodiester bond hydrolysis BP
GO:0097159 organic cyclic compound binding MF
GO:0140097 catalytic activity, acting on DNA MF
GO:1901135 carbohydrate derivative metabolic process BP
GO:1901136 carbohydrate derivative catabolic process BP
GO:1901291 negative regulation of double-strand break repair via single-strand annealing BP
GO:1901292 nucleoside phosphate catabolic process BP
GO:1901360 organic cyclic compound metabolic process BP
GO:1901361 organic cyclic compound catabolic process BP
GO:1901362 organic cyclic compound biosynthetic process BP
GO:1901363 heterocyclic compound binding MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901576 organic substance biosynthetic process BP
GO:1903506 regulation of nucleic acid-templated transcription BP
GO:2000112 regulation of cellular macromolecule biosynthetic process BP
GO:2000779 regulation of double-strand break repair BP
GO:2000780 negative regulation of double-strand break repair BP
GO:2001020 regulation of response to DNA damage stimulus BP
GO:2001021 negative regulation of response to DNA damage stimulus BP
GO:2001141 regulation of RNA biosynthetic process BP
KEGG Term Name Description
map03410 Base excision repair Base excision repair (BER) is the predominant DNA damage repair pathway for the processing of small base lesions, derived from oxidation and alkylation damages. BER is normally defined as DNA repair initiated by lesion-specific DNA glycosylases and completed by either of the two sub-pathways: short-patch BER where only one nucleotide is replaced and long-patch BER where 2-13 nucleotides are replaced. Each sub-pathway of BER relies on the formation of protein complexes that assemble at the site of the DNA lesion and facilitate repair in a coordinated fashion. This process of complex formation appears to provide an increase in specificity and efficiency to the BER pathway, thereby facilitating the maintenance of genome integrity by preventing the accumulation of highly toxic repair intermediates.