PPGR - Gene Detail

Basic Information

Gene Structure

Domain

Regulation&
Interaction

Annotation

Orthologus Group

Expresssion

Pathway

Basic Information

Gene ID	Juni_Chr11.168.g View in Genome Browser
Position	Chr11:1785148-1789701 (+) 4553bp
Gene Type	gene
Gene Description (Protein Product)	DNA excision repair protein
Organism	Juglans nigra
Also AS	AT3G05210

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Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)	Juni_Chr2.1187.g DNA repair endonuclease Juni_Chr13.156.g Zinc finger SWIM domain-containing protein Juni_Chr11.2794.g DNA mismatch repair protein
Regulatory gene	Juni_Chr1.1192.g transcription, DNA-templated Juni_Chr1.243.g Cyclic dof factor Juni_Chr1.2604.g GATA transcription factor

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0000003	reproduction	BP
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	MF
GO:0000109	nucleotide-excision repair complex	CC
GO:0000110	nucleotide-excision repair factor 1 complex	CC
GO:0000710	meiotic mismatch repair	BP
GO:0000724	double-strand break repair via homologous recombination	BP
GO:0000725	recombinational repair	BP
GO:0003674	molecular_function	MF
GO:0003676	nucleic acid binding	MF
GO:0003677	DNA binding	MF
GO:0003684	damaged DNA binding	MF
GO:0003697	single-stranded DNA binding	MF
GO:0003824	catalytic activity	MF
GO:0004518	nuclease activity	MF
GO:0004519	endonuclease activity	MF
GO:0004520	DNA endonuclease activity	MF
GO:0004536	deoxyribonuclease activity	MF
GO:0005488	binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0006139	nucleobase-containing compound metabolic process	BP
GO:0006259	DNA metabolic process	BP
GO:0006281	DNA repair	BP
GO:0006289	nucleotide-excision repair	BP
GO:0006294	nucleotide-excision repair, preincision complex assembly	BP
GO:0006296	obsolete nucleotide-excision repair, DNA incision, 5'-to lesion	BP
GO:0006298	mismatch repair	BP
GO:0006302	double-strand break repair	BP
GO:0006310	DNA recombination	BP
GO:0006312	mitotic recombination	BP
GO:0006725	cellular aromatic compound metabolic process	BP
GO:0006807	nitrogen compound metabolic process	BP
GO:0006950	response to stress	BP
GO:0006974	cellular response to DNA damage stimulus	BP
GO:0007049	cell cycle	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0009314	response to radiation	BP
GO:0009411	response to UV	BP
GO:0009416	response to light stimulus	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009987	cellular process	BP
GO:0010212	response to ionizing radiation	BP
GO:0010213	non-photoreactive DNA repair	BP
GO:0010224	response to UV-B	BP
GO:0010332	response to gamma radiation	BP
GO:0016043	cellular component organization	BP
GO:0016787	hydrolase activity	MF
GO:0016788	hydrolase activity, acting on ester bonds	MF
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	MF
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	MF
GO:0017108	5'-flap endonuclease activity	MF
GO:0022402	cell cycle process	BP
GO:0022414	reproductive process	BP
GO:0022607	cellular component assembly	BP
GO:0032991	protein-containing complex	CC
GO:0033554	cellular response to stress	BP
GO:0033683	obsolete nucleotide-excision repair, DNA incision	BP
GO:0034622	protein-containing complex assembly	BP
GO:0034641	cellular nitrogen compound metabolic process	BP
GO:0034644	cellular response to UV	BP
GO:0043170	macromolecule metabolic process	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0043933	protein-containing complex organization	BP
GO:0044085	cellular component biogenesis	BP
GO:0044237	cellular metabolic process	BP
GO:0044238	primary metabolic process	BP
GO:0044260	cellular macromolecule metabolic process	BP
GO:0044422	obsolete organelle part	CC
GO:0044424	obsolete intracellular part	CC
GO:0044428	obsolete nuclear part	CC
GO:0044446	obsolete intracellular organelle part	CC
GO:0044464	obsolete cell part	CC
GO:0046483	heterocycle metabolic process	BP
GO:0048256	flap endonuclease activity	MF
GO:0050896	response to stimulus	BP
GO:0051321	meiotic cell cycle	BP
GO:0051716	cellular response to stimulus	BP
GO:0061982	meiosis I cell cycle process	BP
GO:0065003	protein-containing complex assembly	BP
GO:0065004	protein-DNA complex assembly	BP
GO:0070522	ERCC4-ERCC1 complex	CC
GO:0070914	UV-damage excision repair	BP
GO:0071214	cellular response to abiotic stimulus	BP
GO:0071478	cellular response to radiation	BP
GO:0071482	cellular response to light stimulus	BP
GO:0071704	organic substance metabolic process	BP
GO:0071824	protein-DNA complex subunit organization	BP
GO:0071840	cellular component organization or biogenesis	BP
GO:0090304	nucleic acid metabolic process	BP
GO:0090305	nucleic acid phosphodiester bond hydrolysis	BP
GO:0097159	organic cyclic compound binding	MF
GO:0104004	cellular response to environmental stimulus	BP
GO:0140097	catalytic activity, acting on DNA	MF
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901363	heterocyclic compound binding	MF
GO:1903046	meiotic cell cycle process	BP
GO:1990391	DNA repair complex	CC

KEGG Term	Name	Description
map03420	Nucleotide excision repair	Nucleotide excision repair (NER) is a mechanism to recognize and repair bulky DNA damage caused by compounds, environmental carcinogens, and exposure to UV-light. In humans hereditary defects in the NER pathway are linked to at least three diseases: xeroderma pigmentosum (XP), Cockayne syndrome (CS), and trichothiodystrophy (TTD). The repair of damaged DNA involves at least 30 polypeptides within two different sub-pathways of NER known as transcription-coupled repair (TCR-NER) and global genome repair (GGR-NER). TCR refers to the expedited repair of lesions located in the actively transcribed strand of genes by RNA polymerase II (RNAP II). In GGR-NER the first step of damage recognition involves XPC-hHR23B complex together with XPE complex (in prokaryotes, uvrAB complex). The following steps of GGR-NER and TCR-NER are similar.