Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Expresssion
Pathway
Basic Information
Gene ID
Juni_Chr9.1748.g
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Position
Chr9:22649420-22665256 (-)
15836bp
Gene Type
gene
Gene Description (Protein Product)
Proteasome activator subunit
Organism
Juglans nigra
Also AS AT3G13330

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Juni_Chr9.989_Juni_Chr9.988.g 26S proteasome non-ATPase regulatory subunit
Juni_Chr9.654.g 26S proteasome non-ATPase regulatory subunit
Juni_Chr9.631.g The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail

Expression Profile
DataSet Number of Samples expressed(TPM>1) Mean Min Max Standard deviation(SD) Coeffcient variation(CV)


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0000502 proteasome complex CC
GO:0003674 molecular_function MF
GO:0005488 binding MF
GO:0005515 protein binding MF
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005829 cytosol CC
GO:0005839 proteasome core complex CC
GO:0006508 proteolysis BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008047 enzyme activator activity MF
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009893 positive regulation of metabolic process BP
GO:0009987 cellular process BP
GO:0010498 proteasomal protein catabolic process BP
GO:0010499 proteasomal ubiquitin-independent protein catabolic process BP
GO:0010604 positive regulation of macromolecule metabolic process BP
GO:0010952 positive regulation of peptidase activity BP
GO:0016504 peptidase activator activity MF
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0030162 regulation of proteolysis BP
GO:0030163 protein catabolic process BP
GO:0030234 enzyme regulator activity MF
GO:0031323 regulation of cellular metabolic process BP
GO:0031325 positive regulation of cellular metabolic process BP
GO:0032268 regulation of protein metabolic process BP
GO:0032270 positive regulation of protein metabolic process BP
GO:0032991 protein-containing complex CC
GO:0042393 histone binding MF
GO:0043085 positive regulation of catalytic activity BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0044093 positive regulation of molecular function BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044464 obsolete cell part CC
GO:0044877 protein-containing complex binding MF
GO:0045862 positive regulation of proteolysis BP
GO:0048518 positive regulation of biological process BP
GO:0048522 positive regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050790 regulation of catalytic activity BP
GO:0050794 regulation of cellular process BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051173 positive regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051247 positive regulation of protein metabolic process BP
GO:0051336 regulation of hydrolase activity BP
GO:0051345 positive regulation of hydrolase activity BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0052547 regulation of peptidase activity BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0061134 peptidase regulator activity MF
GO:0065007 biological regulation BP
GO:0065009 regulation of molecular function BP
GO:0070577 lysine-acetylated histone binding MF
GO:0070628 proteasome binding MF
GO:0071704 organic substance metabolic process BP
GO:0080090 regulation of primary metabolic process BP
GO:0098772 molecular function regulator activity MF
GO:0140030 modification-dependent protein binding MF
GO:0140033 acetylation-dependent protein binding MF
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1902494 catalytic complex CC
GO:1905368 peptidase complex CC
GO:1905369 endopeptidase complex CC
KEGG Term Name Description
map03050 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.