Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
JsiChr11G11195.g
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Position
chr11:18518398-18523273 (+)
4875bp
Gene Type
gene
Gene Description (Protein Product)
exonuclease
Organism
Juglans sigillata
Also AS AT1G18090

Gene Structure

upstream:
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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
JsiChr15G11839.g Component of the post-replicative DNA mismatch repair system (MMR)
JsiChr13G11574.g DNA polymerase
JsiChr12G11603.g DNA polymerase delta
Regulatory gene
JsiChr01G12157.g B3 domain-containing protein
JsiChr01G12647.g Reverse transcriptase (RNA-dependent DNA polymerase)
JsiChr01G12682.g B3 domain-containing transcription factor VRN1-like

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
KEGG Pathway
KEGG Term Name Description
map03430 Mismatch repair DNA mismatch repair (MMR) is a highly conserved biological pathway that plays a key role in maintaining genomic stability. MMR corrects DNA mismatches generated during DNA replication, thereby preventing mutations from becoming permanent in dividing cells. MMR also suppresses homologous recombination and was recently shown to play a role in DNA damage signaling. Defects in MMR are associated with genome-wide instability, predisposition to certain types of cancer including HNPCC, resistance to certain chemotherapeutic agents, and abnormalities in meiosis and sterility in mammalian systems.