Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0000172 | ribonuclease MRP complex | CC |
| GO:0000966 | RNA 5'-end processing | BP |
| GO:0001682 | tRNA 5'-leader removal | BP |
| GO:0003674 | molecular_function | MF |
| GO:0003676 | nucleic acid binding | MF |
| GO:0003723 | RNA binding | MF |
| GO:0005488 | binding | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005732 | sno(s)RNA-containing ribonucleoprotein complex | CC |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
| GO:0006364 | rRNA processing | BP |
| GO:0006396 | RNA processing | BP |
| GO:0006399 | tRNA metabolic process | BP |
| GO:0006725 | cellular aromatic compound metabolic process | BP |
| GO:0006807 | nitrogen compound metabolic process | BP |
| GO:0008033 | tRNA processing | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009987 | cellular process | BP |
| GO:0010467 | gene expression | BP |
| GO:0016070 | RNA metabolic process | BP |
| GO:0016072 | rRNA metabolic process | BP |
| GO:0022613 | ribonucleoprotein complex biogenesis | BP |
| GO:0030677 | ribonuclease P complex | CC |
| GO:0030681 | multimeric ribonuclease P complex | CC |
| GO:0032991 | protein-containing complex | CC |
| GO:0033204 | ribonuclease P RNA binding | MF |
| GO:0034470 | ncRNA processing | BP |
| GO:0034471 | ncRNA 5'-end processing | BP |
| GO:0034641 | cellular nitrogen compound metabolic process | BP |
| GO:0034660 | ncRNA metabolic process | BP |
| GO:0042254 | ribosome biogenesis | BP |
| GO:0043170 | macromolecule metabolic process | BP |
| GO:0044085 | cellular component biogenesis | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0046483 | heterocycle metabolic process | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0071840 | cellular component organization or biogenesis | BP |
| GO:0090304 | nucleic acid metabolic process | BP |
| GO:0097159 | organic cyclic compound binding | MF |
| GO:0099116 | tRNA 5'-end processing | BP |
| GO:1901360 | organic cyclic compound metabolic process | BP |
| GO:1901363 | heterocyclic compound binding | MF |
| GO:1902494 | catalytic complex | CC |
| GO:1902555 | endoribonuclease complex | CC |
| GO:1905348 | endonuclease complex | CC |
| GO:1990904 | ribonucleoprotein complex | CC |
| KEGG Term | Name | Description |
|---|---|---|
| map03008 | Ribosome biogenesis in eukaryotes | Ribosomes are the cellular factories responsible for making proteins. In eukaryotes, ribosome biogenesis involves the production and correct assembly of four rRNAs and about 80 ribosomal proteins. It requires hundreds of factors not present in the mature particle. In the absence of these proteins, ribosome biogenesis is stalled and cell growth is terminated even under optimal growth conditions. The primary pre-rRNA transcript is assembled into the 90S pre-ribosome, which contains both 40S and 60S assembly factors. Within this complex, the pre-rRNA is cleaved. pre-60S ribosomes are subjected to several sequential processing steps in the nucleoplasm involving numerous assembly intermediates before it is exported to the cytoplasm and matured into the 60S ribosomal subunit. The pre-40S ribosome is matured to the small ribosomal subunit in the cytoplasm by cleavage. |

