PPGR - Gene Detail

Basic Information

Gene ID	MD00G1020300.v1.1 View in Genome Browser
Position	Chr00:3719459-3723511 (+) 4052bp
Gene Type	gene
Gene Description (Protein Product)	RESISTANCE protein
Organism	Malus domestica
Also AS	MD00G1020300AT5G17680

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Regulatory gene

MD00G1000500.v1.1 Myb family transcription factor

MD00G1001000.v1.1 Growth-regulating factor

MD00G1032600.v1.1 SANT SWI3; ADA2; N-CoR and TFIIIB'' DNA-binding domains

Load All Networks

Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

GO Term	Description	GO Category
GO:0002218	activation of innate immune response	BP
GO:0002252	immune effector process	BP
GO:0002253	activation of immune response	BP
GO:0002376	immune system process	BP
GO:0002682	regulation of immune system process	BP
GO:0002684	positive regulation of immune system process	BP
GO:0003674	molecular_function	MF
GO:0005488	binding	MF
GO:0005515	protein binding	MF
GO:0005575	cellular_component	CC
GO:0005622	intracellular anatomical structure	CC
GO:0005623	obsolete cell	CC
GO:0005634	nucleus	CC
GO:0006950	response to stress	BP
GO:0006952	defense response	BP
GO:0006955	immune response	BP
GO:0007154	cell communication	BP
GO:0007165	signal transduction	BP
GO:0008150	biological_process	BP
GO:0008219	cell death	BP
GO:0009314	response to radiation	BP
GO:0009416	response to light stimulus	BP
GO:0009605	response to external stimulus	BP
GO:0009607	response to biotic stimulus	BP
GO:0009615	response to virus	BP
GO:0009617	response to bacterium	BP
GO:0009626	plant-type hypersensitive response	BP
GO:0009628	response to abiotic stimulus	BP
GO:0009639	response to red or far red light	BP
GO:0009870	innate immune response-activating signaling pathway	BP
GO:0009987	cellular process	BP
GO:0010114	response to red light	BP
GO:0012501	programmed cell death	BP
GO:0012505	endomembrane system	CC
GO:0016020	membrane	CC
GO:0023052	signaling	BP
GO:0031347	regulation of defense response	BP
GO:0031349	positive regulation of defense response	BP
GO:0033554	cellular response to stress	BP
GO:0034050	programmed cell death induced by symbiont	BP
GO:0042742	defense response to bacterium	BP
GO:0042802	identical protein binding	MF
GO:0043207	response to external biotic stimulus	BP
GO:0043226	organelle	CC
GO:0043227	membrane-bounded organelle	CC
GO:0043229	intracellular organelle	CC
GO:0043231	intracellular membrane-bounded organelle	CC
GO:0044424	obsolete intracellular part	CC
GO:0044464	obsolete cell part	CC
GO:0045087	innate immune response	BP
GO:0045088	regulation of innate immune response	BP
GO:0045089	positive regulation of innate immune response	BP
GO:0048518	positive regulation of biological process	BP
GO:0048583	regulation of response to stimulus	BP
GO:0048584	positive regulation of response to stimulus	BP
GO:0050776	regulation of immune response	BP
GO:0050778	positive regulation of immune response	BP
GO:0050789	regulation of biological process	BP
GO:0050794	regulation of cellular process	BP
GO:0050896	response to stimulus	BP
GO:0051607	defense response to virus	BP
GO:0051704	obsolete multi-organism process	BP
GO:0051707	response to other organism	BP
GO:0051716	cellular response to stimulus	BP
GO:0065007	biological regulation	BP
GO:0080134	regulation of response to stress	BP
GO:0098542	defense response to other organism	BP

KEGG Term	Name	Description
map04626	Plant-pathogen interaction	Plants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pathogens by cell-surface pattern-recognition receptors (PRRs) and is referred to as PAMP-triggered immunity (PTI). Activation of FLS2 and EFR triggers MAPK signaling pathway that activates defense genes for antimictobial compounds. The increase in the cytosolic Ca2+ concentration is also a regulator for production of reactive oxygen species and localized programmed cell death/hypersensitive response. The secondary response is called effector-triggered immunity (ETI). Pathogens can acquire the ability to suppress PTI by directly injecting effector proteins into the plant cell through secretion systems. In addition, pathogens can manipulate plant hormone signaling pathways to evade host immune responses using coronatine toxin. Some plants possess specific intracellular surveillance proteins (R proteins) to monitor the presence of pathogen virulence proteins. This ETI occurs with localized programmed cell death to arrest pathogen growth, resulting in cultivar-specific disease resistance.