PPGR - Gene Detail

Basic Information

Gene ID	MD04G1011900.v1.1 View in Genome Browser
Position	Chr04:1342274-1345372 (-) 3098bp
Gene Type	gene
Gene Description (Protein Product)	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Organism	Malus domestica
Also AS	MD04G1011900AT5G60390

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

MD09G1001300.v1.1 ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors; where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state; facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently; the homodimer reverts towards the open dimer state; lowering its affinity for the membrane-bound receptor; and returning it to the cytosol to initiate a new round of targeting

MD08G1244100.v1.1 Elongation factor

MD15G1438400.v1.1 Elongation factor

Regulatory gene

MD00G1115200.v1.1 Dof zinc finger protein

MD00G1125100.v1.1 Cyclic dof factor

MD01G1040700.v1.1 AP2-like ethylene-responsive transcription factor

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Expression Profile

DataSet	Number of Samples expressed(TPM>1)	Mean	Min	Max	Standard deviation(SD)	Coeffcient variation(CV)

Select Expression

Pathway

KEGG Term	Name	Description
map03013	RNA transport	RNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) via mobile export receptors. The majority of RNAs, such as tRNAs, rRNAs, and U snRNAs, are transported by specific export receptors, which belong to the karyopherin-beta family proteins. A feature of karyopherins is their regulation by the small GTPase Ran. However, general mRNA export is mechanistically different. Nuclear export of mRNAs is functionally coupled to different steps in gene expression processes, such as transcription, splicing, 3'-end formation and even translation.