Basic Information
Gene Structure
Domain
Regulation&
Interaction
Annotation
Orthologus Group
Pathway
Basic Information
Gene ID
Poman.16G082100.v1.1
View in Genome Browser
Position
Chr16:11328934-11335278 (+)
6344bp
Gene Type
gene
Gene Description (Protein Product)
Proteasome Inhibitor
Organism
Populus nigra x maximowiczii
Also AS Poman.16G082100AT3G53970Potri.016G103800.v4.1

Gene Structure

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Domain
Database EntryID E-Value Start end InterPro ID Description

Regulation&Interaction
Protein-protein interaction (PPI)
Poman.18G031100.v1.1 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH
Poman.17G053100.v1.1 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH
Poman.18G111100.v1.1 The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH

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Annotation

Orthologous Group
Orthologous ID Species Number All hits in PereRegDB Hits of this species Orthologous Detail


Pathway
Go Pathway KEGG Pathway
GO Term Description GO Category
GO:0005575 cellular_component CC
GO:0005622 intracellular anatomical structure CC
GO:0005623 obsolete cell CC
GO:0005634 nucleus CC
GO:0005737 cytoplasm CC
GO:0005783 endoplasmic reticulum CC
GO:0005886 plasma membrane CC
GO:0006508 proteolysis BP
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0006807 nitrogen compound metabolic process BP
GO:0008150 biological_process BP
GO:0008152 metabolic process BP
GO:0009056 catabolic process BP
GO:0009057 macromolecule catabolic process BP
GO:0009719 response to endogenous stimulus BP
GO:0009725 response to hormone BP
GO:0009733 response to auxin BP
GO:0009892 negative regulation of metabolic process BP
GO:0009894 regulation of catabolic process BP
GO:0009895 negative regulation of catabolic process BP
GO:0009987 cellular process BP
GO:0010033 response to organic substance BP
GO:0010605 negative regulation of macromolecule metabolic process BP
GO:0012505 endomembrane system CC
GO:0016020 membrane CC
GO:0019222 regulation of metabolic process BP
GO:0019538 protein metabolic process BP
GO:0019941 modification-dependent protein catabolic process BP
GO:0030162 regulation of proteolysis BP
GO:0030163 protein catabolic process BP
GO:0031323 regulation of cellular metabolic process BP
GO:0031324 negative regulation of cellular metabolic process BP
GO:0031329 regulation of cellular catabolic process BP
GO:0031330 negative regulation of cellular catabolic process BP
GO:0032268 regulation of protein metabolic process BP
GO:0032269 negative regulation of protein metabolic process BP
GO:0032870 cellular response to hormone stimulus BP
GO:0042176 regulation of protein catabolic process BP
GO:0042177 negative regulation of protein catabolic process BP
GO:0042221 response to chemical BP
GO:0043170 macromolecule metabolic process BP
GO:0043226 organelle CC
GO:0043227 membrane-bounded organelle CC
GO:0043229 intracellular organelle CC
GO:0043231 intracellular membrane-bounded organelle CC
GO:0043632 modification-dependent macromolecule catabolic process BP
GO:0044237 cellular metabolic process BP
GO:0044238 primary metabolic process BP
GO:0044248 cellular catabolic process BP
GO:0044257 protein catabolic process BP
GO:0044260 cellular macromolecule metabolic process BP
GO:0044265 cellular macromolecule catabolic process BP
GO:0044267 protein metabolic process BP
GO:0044424 obsolete intracellular part CC
GO:0044444 obsolete cytoplasmic part CC
GO:0044464 obsolete cell part CC
GO:0045861 negative regulation of proteolysis BP
GO:0048519 negative regulation of biological process BP
GO:0048523 negative regulation of cellular process BP
GO:0050789 regulation of biological process BP
GO:0050794 regulation of cellular process BP
GO:0050896 response to stimulus BP
GO:0051171 regulation of nitrogen compound metabolic process BP
GO:0051172 negative regulation of nitrogen compound metabolic process BP
GO:0051246 regulation of protein metabolic process BP
GO:0051248 negative regulation of protein metabolic process BP
GO:0051603 proteolysis involved in protein catabolic process BP
GO:0051716 cellular response to stimulus BP
GO:0060255 regulation of macromolecule metabolic process BP
GO:0061136 regulation of proteasomal protein catabolic process BP
GO:0065007 biological regulation BP
GO:0070887 cellular response to chemical stimulus BP
GO:0071310 cellular response to organic substance BP
GO:0071365 cellular response to auxin stimulus BP
GO:0071495 cellular response to endogenous stimulus BP
GO:0071704 organic substance metabolic process BP
GO:0071944 cell periphery CC
GO:0080090 regulation of primary metabolic process BP
GO:1901564 organonitrogen compound metabolic process BP
GO:1901565 organonitrogen compound catabolic process BP
GO:1901575 organic substance catabolic process BP
GO:1901799 negative regulation of proteasomal protein catabolic process BP
GO:1903050 regulation of proteolysis involved in protein catabolic process BP
GO:1903051 negative regulation of proteolysis involved in protein catabolic process BP
GO:1903362 regulation of protein catabolic process BP
GO:1903363 negative regulation of protein catabolic process BP
KEGG Term Name Description
map03050 Proteasome The proteasome is a protein-destroying apparatus involved in many essential cellular functions, such as regulation of cell cycle, cell differentiation, signal transduction pathways, antigen processing for appropriate immune responses, stress signaling, inflammatory responses, and apoptosis. It is capable of degrading a variety of cellular proteins in a rapid and timely fashion and most substrate proteins are modified by ubiquitin before their degradation by the proteasome. The proteasome is a large protein complex consisting of a proteolytic core called the 20S particle and ancillary factors that regulate its activity in various ways. The most common form is the 26S proteasome containing one 20S core particle and two 19S regulatory particles that enable the proteasome to degrade ubiquitinated proteins by an ATP-dependent mechanism. Another form is the immunoproteasome containing two 11S regulatory particles, PA28 alpha and PA28 beta, which are induced by interferon gamma under the conditions of intensified immune response. Other regulatory particles include PA28 gamma and PA200. Although PA28 gamma also belongs to a family of activators of the 20S proteasome, it is localized within the nucleus and forms a homoheptamer. PA28 gamma has been implicated in the regulation of cell cycle progression and apoptosis. PA200 has been identified as a large nuclear protein that stimulates proteasomal hydrolysis of peptides.