PPGR - Gene Detail

Basic Information

Gene ID	Poman.16G085900.v1.1 View in Genome Browser
Position	Chr16:12123989-12125258 (-) 1269bp
Gene Type	gene
Gene Description (Protein Product)	Steroid 5-alpha-reductase
Organism	Populus nigra x maximowiczii
Also AS	Poman.16G085900AT2G38050Potri.016G110600.v4.1

upstream:

Domain

Database	EntryID	E-Value	Start	end	InterPro ID	Description

Regulation&Interaction

Protein-protein interaction (PPI)

Poman.17G075700.v1.1 Cytochrome p450

Poman.17G093100.v1.1 Belongs to the sterol desaturase family

Poman.17G044500.v1.1 Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells

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Annotation

Orthologous Group

Orthologous ID	Species Number	All hits in PereRegDB	Hits of this species	Orthologous Detail

Pathway

GO Term	Description	GO Category
GO:0003674	molecular_function	MF
GO:0003824	catalytic activity	MF
GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity	MF
GO:0006629	lipid metabolic process	BP
GO:0006694	steroid biosynthetic process	BP
GO:0008150	biological_process	BP
GO:0008152	metabolic process	BP
GO:0008202	steroid metabolic process	BP
GO:0008610	lipid biosynthetic process	BP
GO:0009058	biosynthetic process	BP
GO:0009917	sterol 5-alpha reductase activity	MF
GO:0010268	brassinosteroid homeostasis	BP
GO:0010817	regulation of hormone levels	BP
GO:0016128	phytosteroid metabolic process	BP
GO:0016129	phytosteroid biosynthetic process	BP
GO:0016131	brassinosteroid metabolic process	BP
GO:0016132	brassinosteroid biosynthetic process	BP
GO:0016229	steroid dehydrogenase activity	MF
GO:0016491	oxidoreductase activity	MF
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	MF
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	MF
GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors	MF
GO:0042445	hormone metabolic process	BP
GO:0042446	hormone biosynthetic process	BP
GO:0042592	homeostatic process	BP
GO:0044238	primary metabolic process	BP
GO:0048878	chemical homeostasis	BP
GO:0050213	progesterone 5-alpha-reductase activity	MF
GO:0055088	lipid homeostasis	BP
GO:0055114	obsolete oxidation-reduction process	BP
GO:0065007	biological regulation	BP
GO:0065008	regulation of biological quality	BP
GO:0071704	organic substance metabolic process	BP
GO:1901360	organic cyclic compound metabolic process	BP
GO:1901362	organic cyclic compound biosynthetic process	BP
GO:1901576	organic substance biosynthetic process	BP
GO:1901615	organic hydroxy compound metabolic process	BP
GO:1901617	organic hydroxy compound biosynthetic process	BP

KEGG Term	Name	Description
map01110	Biosynthesis of secondary metabolites	-
map01100	Metabolic pathways	-
map00905	Brassinosteroid biosynthesis	Brassinosteroids are a group of plant steroid hormones that regulate growth and development. More than fifty naturally occurring brassinosteroids have been identified in a wide range of plant species. The most abundant and widely occurring brassinosteroids are C28 steroids, and among them brassinolide (BL) is the most biologically active. Plants have multiple pathways for biosynthesis of BL, which are derived from the steroid biosynthetic pathway. Two pathways from campestanol to castasterone (CS), C6 oxidation and the late-C6 oxidation pathways, operate in many plants. Another branching pathway, the early-C22 oxidation pathway, was demonstrated using a brassinosteroid-deficient mutant of Arabidopsis thaliana. Recently, a new shortcut pathway from campesterol to 6-deoxotyphasterol was demonstrated by a functional analysis of cytochrome P450 monooxygenases responsible for brassinosteroid biosynthesis. Thus, at least four pathways are involved in the biosynthesis of CS, and CS is further metabolized to BL by lactonization of the B ring.