Basic Information
Gene Structure
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Domain
| Database | EntryID | E-Value | Start | end | InterPro ID | Description |
|---|
Regulation&Interaction
Annotation
Orthologous Group
| Orthologous ID | Species Number | All hits in PereRegDB | Hits of this species | Orthologous Detail |
|---|
Expression Profile
| DataSet | Number of Samples expressed(TPM>1) | Mean | Min | Max | Standard deviation(SD) | Coeffcient variation(CV) |
|---|
Pathway
| GO Term | Description | GO Category |
|---|---|---|
| GO:0003674 | molecular_function | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity | MF |
| GO:0005575 | cellular_component | CC |
| GO:0005622 | intracellular anatomical structure | CC |
| GO:0005623 | obsolete cell | CC |
| GO:0005737 | cytoplasm | CC |
| GO:0005739 | mitochondrion | CC |
| GO:0005759 | mitochondrial matrix | CC |
| GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex | CC |
| GO:0006082 | organic acid metabolic process | BP |
| GO:0006091 | generation of precursor metabolites and energy | BP |
| GO:0006099 | tricarboxylic acid cycle | BP |
| GO:0006101 | citrate metabolic process | BP |
| GO:0008150 | biological_process | BP |
| GO:0008152 | metabolic process | BP |
| GO:0009060 | aerobic respiration | BP |
| GO:0009353 | mitochondrial oxoglutarate dehydrogenase complex | CC |
| GO:0009987 | cellular process | BP |
| GO:0015980 | energy derivation by oxidation of organic compounds | BP |
| GO:0016491 | oxidoreductase activity | MF |
| GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | MF |
| GO:0016903 | oxidoreductase activity, acting on the aldehyde or oxo group of donors | MF |
| GO:0016999 | antibiotic metabolic process | BP |
| GO:0017144 | xenobiotic metabolic process | BP |
| GO:0019752 | carboxylic acid metabolic process | BP |
| GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex | CC |
| GO:0031974 | membrane-enclosed lumen | CC |
| GO:0032991 | protein-containing complex | CC |
| GO:0043226 | organelle | CC |
| GO:0043227 | membrane-bounded organelle | CC |
| GO:0043229 | intracellular organelle | CC |
| GO:0043231 | intracellular membrane-bounded organelle | CC |
| GO:0043233 | organelle lumen | CC |
| GO:0043436 | oxoacid metabolic process | BP |
| GO:0044237 | cellular metabolic process | BP |
| GO:0044238 | primary metabolic process | BP |
| GO:0044281 | small molecule metabolic process | BP |
| GO:0044422 | obsolete organelle part | CC |
| GO:0044424 | obsolete intracellular part | CC |
| GO:0044429 | obsolete mitochondrial part | CC |
| GO:0044444 | obsolete cytoplasmic part | CC |
| GO:0044446 | obsolete intracellular organelle part | CC |
| GO:0044464 | obsolete cell part | CC |
| GO:0045239 | tricarboxylic acid cycle enzyme complex | CC |
| GO:0045240 | dihydrolipoyl dehydrogenase complex | CC |
| GO:0045252 | oxoglutarate dehydrogenase complex | CC |
| GO:0045333 | cellular respiration | BP |
| GO:0055114 | obsolete oxidation-reduction process | BP |
| GO:0070013 | intracellular organelle lumen | CC |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0072350 | tricarboxylic acid metabolic process | BP |
| GO:0098798 | mitochondrial protein-containing complex | CC |
| GO:1902494 | catalytic complex | CC |
| GO:1990204 | oxidoreductase complex | CC |
| GO:1990234 | transferase complex | CC |
| KEGG Term | Name | Description |
|---|---|---|
| map01110 | Biosynthesis of secondary metabolites | - |
| map01100 | Metabolic pathways | - |
| map00020 | Citrate cycle (TCA cycle) | The citrate cycle (TCA cycle, Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. The cycle starts with acetyl-CoA, the activated form of acetate, derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. In a series of reactions two carbons in citrate are oxidized to CO2 and the reaction pathway supplies NADH for use in the oxidative phosphorylation and other metabolic processes. The pathway also supplies important precursor metabolites including 2-oxoglutarate. At the end of the cycle the remaining four-carbon part is transformed back to oxaloacetate. According to the genome sequence data, many organisms seem to lack genes for the full cycle [MD:M00009], but contain genes for specific segments [MD:M00010 M00011]. |

